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Structured Review

Broad Institute Inc ccle rna-seq dataset
Ccle Rna Seq Dataset, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gene+expression+data/ccle+cell+line+gene+expression+data/pm34986355-362-0-7
Average 90 stars, based on 1 article reviews
ccle rna-seq dataset - by Bioz Stars, 2026-11
90/100 stars

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Related Articles

Expressing:

Article Title: Systematic pan‐cancer analysis identifies RBM39 as an immunological and prognostic biomarker
Article Snippet: .. Each tumour cell line's CCLE‐based expression data was obtained from the Broad Institute's Portal ( https://portals.broadinstitute.org/ ). ..

other:

Article Title: Systematic pan-cancer analysis identifies RBM39 as an immunological and prognostic biomarker.
Article Snippet: Each tumour cell line's CCLE- based expression data was obtained from the Broad Institute's Portal (https://porta ls.broad insti tute.org/).

Article Title: Integrative clinical and molecular characterization of translocation renal cell carcinoma.
Article Snippet: Sample concentrations were measured using a NanoDrop 8000 Spectrophotometer (Thermo Fisher Scientific) and sequencing libraries were prepared with poly(A) selection.

Article Title: Genomic and experimental evidence that ALK ATI does not predict single agent sensitivity to ALK inhibitors
Article Snippet: Cell line expression and drug sensitivity data: CCLE 2019 RNA-seq gene expression data for 1019 cell lines were downloaded from the Broad Institute CCLE website ( https://portals.broadinstitute.org/ccle ).

CRISPR:

Article Title: Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma.
Article Snippet: .. We would like to thank the Broad Institute DepMap team for generating and sharing the CRISPR-Cas9 screen data and CCLE gene expression data. ..

Gene Expression:

Article Title: Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma.
Article Snippet: .. We would like to thank the Broad Institute DepMap team for generating and sharing the CRISPR-Cas9 screen data and CCLE gene expression data. ..

Article Title: CD44-hyaluronan mediating endocytosis of iron-platinum alloy nanoparticles induces ferroptotic cell death in mesenchymal-state lung cancer cells with tyrosine kinase inhibitor resistance.
Article Snippet: While tyrosine kinase inhibitor resistance in cancer is a critical issue in the medical field, it is important for clinical testing as well, since it affects the ultimate outcome of cancer therapy.. Yet, no effective solutions have been implemented till date.. Clinical observations after tyrosine kinase inhibitor treatment reveal that acquired resistance inevitably limits the curative effects of non-small cell lung cancer treatment because of mutations in the epidermal growth factor receptor gene, which are accompanied by epithelial-mesenchymal transition.

Sequencing:

Article Title: Allelic expression patterns of imprinted and non-imprinted genes in cancer cell lines from multiple histologies.
Article Snippet: .. The GDC Legacy Archive was later retired; however, the BAM sequencing data for CCLE cell lines are currently a part of the DepMap project at the Broad Institute [69–71]) and are available from the National Cancer for Biotechnology Information Sequence Read Archive (NCBI SRA; accession PRJNA523380) [107] and via the Terra genomics cloud workspace [108]. ..

Article Title: Allelic expression patterns of imprinted and non-imprinted genes in cancer cell lines from multiple histologies
Article Snippet: .. The GDC Legacy Archive was later retired; however, the BAM sequencing data for CCLE cell lines are currently a part of the DepMap project at the Broad Institute [ – ]) and are available from the National Cancer for Biotechnology Information Sequence Read Archive (NCBI SRA; accession PRJNA523380) [ ] and via the Terra genomics cloud workspace [ ]. ..



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(A) Cohen’s h values for pairwise comparisons between 𝒞 and the other two groups: ℬ and ℐ . Primate <t>Specific</t> Ratios are calculated as in . A higher absolute Cohen’s h indicates a greater difference in ratios between the two compared groups. Green bar represents ℬ , orange bar represents ℐ , and blue bars represent 𝒞 . (B) Results of Fisher’s exact tests for pairwise comparisons between each of ℬ , ℐ , and 𝒞 and each control group ( ℱ and ℛ ), together with the comparison between ℱ and ℛ . Primate Specific Ratios are calculated as in . Statistical significance is denoted by asterisks. Results with p-values less than 0.01 are indicated by two asterisks (**), results with p-values less than 0.05 are indicated by one asterisk (*), and all other results are marked as ns . Green bar represents ℬ , orange bar represents ℐ , blue bar represents 𝒞 , gray bars represent ℛ , and purple bars represent ℱ . (C) The number of tissues corresponding to each quantile for the brain <t>genes</t> and immune-related genes. Green bars represent ℬ , orange bars represent ℐ , and gray bars represent all genes that have at least one highly expressed <t>tissue</t> in Human Protein Atlas [ , ]. (D) The number and ratio of genes highly expressed specifically in brain tissues or immune-related tissues, out of 1019 brain genes and 586 immune-related genes, respectively.
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Image Search Results


Journal: Cell Genomics

Article Title: MultiSP deciphers tissue structure and multicellular communication from spatial multi-omics data

doi: 10.1016/j.xgen.2026.101141

Figure Lengend Snippet:

Article Snippet: 10× Visium human tonsil gene and protein expression data , 10× Genomics , https://www.10xgenomics.com/resources/datasets/gene-protein-expression-library-of-human-tonsil-cytassist-ffpe-2-standard.

Techniques: Expressing, Software

(A) Cohen’s h values for pairwise comparisons between 𝒞 and the other two groups: ℬ and ℐ . Primate Specific Ratios are calculated as in . A higher absolute Cohen’s h indicates a greater difference in ratios between the two compared groups. Green bar represents ℬ , orange bar represents ℐ , and blue bars represent 𝒞 . (B) Results of Fisher’s exact tests for pairwise comparisons between each of ℬ , ℐ , and 𝒞 and each control group ( ℱ and ℛ ), together with the comparison between ℱ and ℛ . Primate Specific Ratios are calculated as in . Statistical significance is denoted by asterisks. Results with p-values less than 0.01 are indicated by two asterisks (**), results with p-values less than 0.05 are indicated by one asterisk (*), and all other results are marked as ns . Green bar represents ℬ , orange bar represents ℐ , blue bar represents 𝒞 , gray bars represent ℛ , and purple bars represent ℱ . (C) The number of tissues corresponding to each quantile for the brain genes and immune-related genes. Green bars represent ℬ , orange bars represent ℐ , and gray bars represent all genes that have at least one highly expressed tissue in Human Protein Atlas [ , ]. (D) The number and ratio of genes highly expressed specifically in brain tissues or immune-related tissues, out of 1019 brain genes and 586 immune-related genes, respectively.

Journal: PLOS One

Article Title: Comparative genomics of human brain and immune gene preservation across species

doi: 10.1371/journal.pone.0348713

Figure Lengend Snippet: (A) Cohen’s h values for pairwise comparisons between 𝒞 and the other two groups: ℬ and ℐ . Primate Specific Ratios are calculated as in . A higher absolute Cohen’s h indicates a greater difference in ratios between the two compared groups. Green bar represents ℬ , orange bar represents ℐ , and blue bars represent 𝒞 . (B) Results of Fisher’s exact tests for pairwise comparisons between each of ℬ , ℐ , and 𝒞 and each control group ( ℱ and ℛ ), together with the comparison between ℱ and ℛ . Primate Specific Ratios are calculated as in . Statistical significance is denoted by asterisks. Results with p-values less than 0.01 are indicated by two asterisks (**), results with p-values less than 0.05 are indicated by one asterisk (*), and all other results are marked as ns . Green bar represents ℬ , orange bar represents ℐ , blue bar represents 𝒞 , gray bars represent ℛ , and purple bars represent ℱ . (C) The number of tissues corresponding to each quantile for the brain genes and immune-related genes. Green bars represent ℬ , orange bars represent ℐ , and gray bars represent all genes that have at least one highly expressed tissue in Human Protein Atlas [ , ]. (D) The number and ratio of genes highly expressed specifically in brain tissues or immune-related tissues, out of 1019 brain genes and 586 immune-related genes, respectively.

Article Snippet: There are six types of data used in this work: (1) CDS (coding sequence) data of 32 primate species and 4 non-primate species [ , ]; (2) tissue specific gene expression data obtained from the Human Protein Atlas 23.0 [ , ]; (3) 1360 human genes highly expressed in the brain or the immune system [ , ]; (4) 295 random human genes selected using the random.sample() function in Python 3.10.8; (5) 369 human genes each from a distinct HGNC [ ] gene family group; and (6) protein sequences of the genes obtained from UniProt [ ].

Techniques: Control, Comparison