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BioCarta functional annotation chart
Functional Annotation Chart, supplied by BioCarta, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/functional+annotation+chart/functional+annotation+cluster+tool/pm32572159-94-27-30
Average 90 stars, based on 1 article reviews
functional annotation chart - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses.
Article Snippet: WARS1 binds PI(4,5)P2 at cell membrane for free-form secre (A) WARS1 interactome ontology classified using the functional annotation tool D BioCarta pathways are shown. (B) PI(4,5)P2- and CAPN2-related signaling. (C) WARS1, TNF-a, and IL-6 levels in human PBMC culture SUPs treated with th (D) Immunoblot analysis of WARS1 in subcellular fractions from THP-1 cells treat were detected to confirm the cytoplasm (CYTO) and PM fractions, respectively.

Functional Assay:

Article Title: Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms.
Article Snippet: .. Adjusted P value in red-blue color scale. b Venn diagram of deregulated genes are shown for CALR type 1 and type 2. c David functional analysis using functional annotation chart (Biocarta) indicates five pathways. ..

Article Title: Study on the multi-targets mechanism of triphala on cardio-cerebral vascular diseases based on network pharmacology.
Article Snippet: .. Additionally, main functional annotation clusters ranked by the Biocarta functional annotation cluster tool are presented in Fig. 4C. ..

Article Title: The Combination of Three Components Derived from Sheng MaiSan Protects Myocardial Ischemic Diseases and Inhibits Oxidative Stress via Modulating MAPKs and JAK2-STAT3 Signaling Pathways Based on Bioinformatics Approach
Article Snippet: .. The top 10 main functional annotation clusters were displayed in Table and Figure ranked by the Biocarta functional annotation cluster tool. ..

Article Title: Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages.
Article Snippet: .. The membrane proteins identified only from ATP-stimulated samples (Supplemental Table II) were further analyzed by the functional annotation tool DAVID, and results of GO term enrichment reflecting the highest p values from BioCarta and Kyoto Encyclopedia of Genes and Genomes pathway analysis are shown. (B) Human macrophages were left unstimulated or were stimulated with 3 mM ATP for 0.5 h. Subsequently, cell lysates were collected, and the expression of calpain-1 (CANP-1) and calpain-2 (CANP-2) was analyzed by Western blotting. (C) Cells were stimulated as in (B). ..

Article Title: The Combination of Three Components Derived from Sheng MaiSan Protects Myocardial Ischemic Diseases and Inhibits Oxidative Stress via Modulating MAPKs and JAK2-STAT3 Signaling Pathways Based on Bioinformatics Approach
Article Snippet: A variety of databases such as GeneGo, KEGG and Biocarta collect cured pathways ( ). .. In our current study, the functional annotation clusters were divided into groups of similar annotations employing Biocarta functional annotation tool in accordance with the enrichment scores. ..

Article Title: Identification of driver pathways in cancer based on combinatorial patterns of somatic gene mutations.
Article Snippet: .. We used the functional annotation tool of DAVID for BIOCARTA pathway enrichment. .. We found that one of the significant BIOCARTA pathways, First Multivalent Nuclear Factor, is a novel pathway which hasn’t been proved a connection with GBM previously.

Article Title: The Combination of Three Components Derived from Sheng MaiSan Protects Myocardial Ischemic Diseases and Inhibits Oxidative Stress via Modulating MAPKs and JAK2-STAT3 Signaling Pathways Based on Bioinformatics Approach
Article Snippet: .. Biocarta functional annotation tool was applied to group the functional annotation clusters with similar annotations on the basis of the enrichment scores. ..

Membrane:

Article Title: Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages.
Article Snippet: .. The membrane proteins identified only from ATP-stimulated samples (Supplemental Table II) were further analyzed by the functional annotation tool DAVID, and results of GO term enrichment reflecting the highest p values from BioCarta and Kyoto Encyclopedia of Genes and Genomes pathway analysis are shown. (B) Human macrophages were left unstimulated or were stimulated with 3 mM ATP for 0.5 h. Subsequently, cell lysates were collected, and the expression of calpain-1 (CANP-1) and calpain-2 (CANP-2) was analyzed by Western blotting. (C) Cells were stimulated as in (B). ..

Expressing:

Article Title: Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages.
Article Snippet: .. The membrane proteins identified only from ATP-stimulated samples (Supplemental Table II) were further analyzed by the functional annotation tool DAVID, and results of GO term enrichment reflecting the highest p values from BioCarta and Kyoto Encyclopedia of Genes and Genomes pathway analysis are shown. (B) Human macrophages were left unstimulated or were stimulated with 3 mM ATP for 0.5 h. Subsequently, cell lysates were collected, and the expression of calpain-1 (CANP-1) and calpain-2 (CANP-2) was analyzed by Western blotting. (C) Cells were stimulated as in (B). ..

Western Blot:

Article Title: Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages.
Article Snippet: .. The membrane proteins identified only from ATP-stimulated samples (Supplemental Table II) were further analyzed by the functional annotation tool DAVID, and results of GO term enrichment reflecting the highest p values from BioCarta and Kyoto Encyclopedia of Genes and Genomes pathway analysis are shown. (B) Human macrophages were left unstimulated or were stimulated with 3 mM ATP for 0.5 h. Subsequently, cell lysates were collected, and the expression of calpain-1 (CANP-1) and calpain-2 (CANP-2) was analyzed by Western blotting. (C) Cells were stimulated as in (B). ..



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