visualization utilized clinx chemiscope (Clinx Science)
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Visualization Utilized Clinx Chemiscope, supplied by Clinx Science, used in various techniques. Bioz Stars score: 96/100, based on 3729 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fluorescence+visualization/ChemiScope+6100+chemiluminescence+and+fluorescence+imaging+system/pm40449785-100-0-2
Average 96 stars, based on 3729 article reviews
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Imaging:Article Title: Hematopoietic progenitor kinase 1 inhibitor BGB-15025 induces apoptosis in acute myeloid leukemia cells through the cell cycle pathway and mitogen-activated protein kinase/extracellular signal-regulated kinase pathway signaling axis Article Snippet: Following three 15-min TBST washes, membranes were incubated for 1 h at room temperature with species-matched horseradish peroxidase-conjugated secondary antibodies (goat anti-rabbit HS101-01 and goat anti-mouse HS201-01; TransGen Biotech, Beijing, China). .. Protein bands were visualized using the Article Title: Astragaloside IV attenuates cisplatin-induced acute kidney injury by suppressing KAT5-mediated NLRP3 acetylation and inflammasome activation. Article Snippet: Cisplatin, a highly effective chemotherapeutic agent, is subject to significant clinical limitations due to its doselimiting nephrotoxicity, which can result in acute kidney injury (AKI) and chronic kidney disease.. The present study investigates the renoprotective potential of Astragaloside IV (AS-IV), a primary bioactive component of Astragalus membranaceus, against cisplatin-induced nephrotoxicity (CIAKI) and elucidates its underlying molecular mechanism.. In a murine model, AS-IV treatment was demonstrated to significantly ameliorate cisplatininduced renal dysfunction, histopathological damage, and the upregulation of markers associated with inflammation and fibrosis. Article Title: A “One-Stone-Three-Birds” Inspired Nanoplatform for Multitargeted Ulcerative Colitis Therapy via Combined Aryl Hydrocarbon Receptor Activation and Reactive Oxygen Species Scavenging Article Snippet: .. Protein bands were visualized using a Article Title: Dual-targeting of mitochondrial and c-Myc G-quadruplexes by a photoactive coumarin-benzothiazolium conjugate inhibits triple-negative breast cancer cell growth. Article Snippet: Targeting G-quadruplexes (G4s) presents a promising strategy for cancer therapy, but early-generation ligands often lack tumor selectivity.. This study identified X-3, a novel photoactive coumarin-benzothiazolium conjugate, as a dual-targeted photosensitizer against triple-negative breast cancer (TNBC).. X-3 localized to both mitochondria and the nucleus, where it specifically bound to mitochondrial and c-Myc G4s with high affinity. Control:Article Title: Structural basis for RNA synthesis and inhibition of the orthobunyavirus polymerase. Article Snippet: Lysates were resolved on 10% SDS-PAGE, transferred to PVDF membrane, and probed with mouse anti-FLAG (Abclonal, AE005; 1:3,000) and HRP-conjugated goat antimouse IgG (Abclonal, AS003; 1:5,000). .. Signals were detected with ChemiScope 6100 (Clinx). |
