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Data Sciences International buxco finepointe inhalation exposure system
Buxco Finepointe Inhalation Exposure System, supplied by Data Sciences International, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/finepoint+software/finepointe+software/pm41643263-119-40-45
Average 86 stars, based on 1 article reviews
buxco finepointe inhalation exposure system - by Bioz Stars, 2026-10
86/100 stars

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Amplification:

Article Title: GABAergic Inhibition from the Nucleus Tractus Solitarius to Ventrolateral Medulla Phox2b Neurons Modulates Central Respiratory Chemoreflex and Ventilatory Homeostasis.
Article Snippet: Central respiratory chemoreception is a vital homeostatic mechanism maintaining arterial blood gas levels.. Central respiratory chemoreceptors in the retrotrapezoid nucleus (RTN) and nucleus tractus solitarius (NTS) form interconnected circuits to regulate respiratory homeostasis.. We hypothesized that NTS GABAergic neurons (NTSGABA) modulate hypercapnic ventilatory responses by targeting ventrolateral medulla Phox2b neurons (VLMPhox2b), particularly Phox2b-expressing RTN neurons.

Software:

Article Title: BRL-50481 Ameliorates Lung Inflammation in a Murine Model of Ovalbumin-Induced Allergic Asthma with Co-Exposure to Lipopolysaccharide.
Article Snippet: .. All mice were acclimated for 5 min on a plethysmograph and exposed to methacholine (4, 8, or 16 mg/mL) for 1 min. After methacholine exposure, AHR was automatically measured using FinePointe software (Data Sciences International, MA, USA) for 5 min. All data were expressed as the ratio of the value in phosphate-buffered saline (PBS; 0 mg/mL). ..

Article Title: Prenatal exposure to particulate matter impairs offspring behavior via hippocampal NMDA receptor reduction: an in vivo and ex vivo study.
Article Snippet: .. Lung function indicators were automatically calculated with FinePointe software (Data Sciences International, St. Paul, MN, USA). .. Total RNA was extracted from frozen mouse brain tissue using TRIzol (Invitrogen, CA, USA) and the easy-spin Total RNA Extraction Kit (iNtRON Biotechnology, Kyunggi-do, Korea) according to the manufacturers’ instructions.

Article Title: Hyaluronic acid-based microgels loaded with fluticasone furoate for bleomycin-induced acute lung injury treatment
Article Snippet: .. Data was recorded using DSI FinePointe WBP software (Data Sciences International, St. Paul, MN, USA). ..

Article Title: Calcaratarin D, A Labdane Diterpenoid, Attenuates Bleomycin-Induced Pulmonary Fibrosis by Blocking Wnt/β-Catenin Signaling Pathway.
Article Snippet: Briefly, the trachea was intubated with a cannula that was connected to a forced pulmonary maneuver system (Data Sciences International, St. Paul, MN). .. Forced vital capacity (FVC), static compliance (Cchord), and dynamic compliance (Cdyn) were recorded and analysed using FinePointe software (Data Sciences International). .. Lung homogenates were prepared in PBS containing proteinase inhibitor using tissue homogenizer Precellys®24 (Bertin Technologies SAS, Montigny-le-Bretonneux, France).

Article Title: Sex-Specific Pathophysiological Signatures in Allometric Dosing-Controlled Bleomycin Acute Lung Injury Model
Article Snippet: .. Data was recorded using DSI FinePointe WBP software (Data Sciences International, St. Paul, MN, USA). ..

Saline:

Article Title: BRL-50481 Ameliorates Lung Inflammation in a Murine Model of Ovalbumin-Induced Allergic Asthma with Co-Exposure to Lipopolysaccharide.
Article Snippet: .. All mice were acclimated for 5 min on a plethysmograph and exposed to methacholine (4, 8, or 16 mg/mL) for 1 min. After methacholine exposure, AHR was automatically measured using FinePointe software (Data Sciences International, MA, USA) for 5 min. All data were expressed as the ratio of the value in phosphate-buffered saline (PBS; 0 mg/mL). ..

Injection:

Article Title: Melatonin inhibits ferroptosis by activating CREB-GPX4/ferritin axis in cigarette smoke-induced chronic obstructive pulmonary disease.
Article Snippet: .. After mice were anesthetized with 1% pentobarbital (i.p. injection dose [ml] = mouse body weight [g] × 4/1000), we tracheostomized, and placed them in a Buxco Small Animal Whole Body Plethysmograph, and subjected them to pulmonary-function testing (PFT) using a Buxco FinePointe Inhalation Exposure System (Data Sciences International [DSI], New Brighton, MN, USA). ..



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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography <t>(WBP)</t> measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.
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( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography (WBP) measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.

Journal: bioRxiv

Article Title: Sex-Specific Pathophysiological Signatures in Allometric Dosing-Controlled Bleomycin Acute Lung Injury Model

doi: 10.64898/2026.03.10.710851

Figure Lengend Snippet: ( A ) Representative waveform traces demonstrating altered breathing patterns in SHAM and bleomycin-treated (BLEO) male and female rats in both matching approaches. ( B-G ). Non-invasive whole-body plethysmography (WBP) measurements showing ( B ) respiratory rate (RR, breaths/min), ( C ) tidal normalized to body weight (TV/kg, mL/kg), ( D ) minute ventilation normalized to body weight (MV/kg, ml/min/kg), ( E ) mid-tidal expiratory flow (EF50, mL/s), ( F ) enhanced pause (Penh), and ( G ) relative time to peak expiratory flow (Rpef). Invasive lung mechanics measurements of ( H ) airway resistance (RI, cmH 2 O·s/mL) and ( I ) dynamic compliance (Cdyn, mL/cmH 2 O). Data are presented as mean ± SEM. For B-G, age matched cohort: n = 10 per group; BW matched group: n = 6 males, n = 8 females. For H-I, age matched group: n = 5-7 for SHAM, n = 7-9 for BLEO; BW-matched group: n = 5-6 for SHAM, n = 7-8 for BLEO. *p < 0.05, ns = not significant. Statistical analysis performed using two-way ANOVA with Tukey’s multiple comparisons test.

Article Snippet: Data was recorded using DSI FinePointe WBP software (Data Sciences International, St. Paul, MN, USA).

Techniques: