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factor 1 receptor csf1r antagonist pexidartinib  (MedChemExpress)


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    MedChemExpress factor 1 receptor csf1r antagonist pexidartinib
    Factor 1 Receptor Csf1r Antagonist Pexidartinib, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 196 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/factor+1/Pexidartinib/pm42009179-63-2-9
    Average 97 stars, based on 196 article reviews
    factor 1 receptor csf1r antagonist pexidartinib - by Bioz Stars, 2026-10
    97/100 stars

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    Imaging:

    Article Title: Astrocytes instructively regulate neuronal translation
    Article Snippet: For microglia depletion, 1μM PLX-3397 (MedChemExpress HY-16749) was added to culture medium on DIV3 and until sample collection.

    Real-time Polymerase Chain Reaction:

    Article Title: Astrocytes instructively regulate neuronal translation
    Article Snippet: For microglia depletion, 1μM PLX-3397 (MedChemExpress HY-16749) was added to culture medium on DIV3 and until sample collection.



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    ( A ) The intracellular HMGB1 after different treatments toward 4T1 cells. ( B ) Immunofluorescence images showing CRT expression on the cell membrane of 4T1 cells, and ( C ) corresponding fluorescence quantification. Scale bar = 50 μm. ( D ) Immunofluorescence images of CD206 expression in RAW264.7 macrophages, and ( E ) quantitative analysis. Scale bar = 50 μm. ( F ) Immunofluorescence images of CD86 expression in RAW264.7 macrophages, and ( G ) quantitative analysis. Scale bar = 50 μm. ( H ) Secretion levels of anti-inflammatory cytokine IL-10 and ( I ) pro-inflammatory cytokine TNF-α from RAW264.7 cells after various treatments. ( J ) Western blot analysis of p-IRF3 expression in RAW264.7 cells, and ( K ) quantification of p-IRF3 band intensity. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

    Journal: International Journal of Nanomedicine

    Article Title: A Multifunctional Metal-Based Nanomedicine for Copper Sequestration, in situ Toxification, and Immune Activation Against Metastatic Cancer

    doi: 10.2147/IJN.S580749

    Figure Lengend Snippet: ( A ) The intracellular HMGB1 after different treatments toward 4T1 cells. ( B ) Immunofluorescence images showing CRT expression on the cell membrane of 4T1 cells, and ( C ) corresponding fluorescence quantification. Scale bar = 50 μm. ( D ) Immunofluorescence images of CD206 expression in RAW264.7 macrophages, and ( E ) quantitative analysis. Scale bar = 50 μm. ( F ) Immunofluorescence images of CD86 expression in RAW264.7 macrophages, and ( G ) quantitative analysis. Scale bar = 50 μm. ( H ) Secretion levels of anti-inflammatory cytokine IL-10 and ( I ) pro-inflammatory cytokine TNF-α from RAW264.7 cells after various treatments. ( J ) Western blot analysis of p-IRF3 expression in RAW264.7 cells, and ( K ) quantification of p-IRF3 band intensity. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.

    Article Snippet: The calreticulin (CRT), CD206, CD86, and phospho-interferon regulatory factor 3 (p-IRF3) antibody were purchased from Proteintech Group, Inc. (Wuhan, China).

    Techniques: Immunofluorescence, Expressing, Membrane, Fluorescence, Analysis, Western Blot