rabbit polyclonal anti human trpm8 antibody (Alomone Labs)
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rabbit polyclonal anti human trpm8 antibody
Rabbit Polyclonal Anti Human Trpm8 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 44 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/double-loop+control/Anti-TRPM8+(extracellular)+Antibody/pmc06176370-73-5-10
Average 95 stars, based on 44 article reviews
Rabbit Polyclonal Anti Human Trpm8 Antibody, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 44 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/double-loop+control/Anti-TRPM8+(extracellular)+Antibody/pmc06176370-73-5-10
Average 95 stars, based on 44 article reviews
rabbit polyclonal anti human trpm8 antibody - by Bioz Stars,
2026-09
95/100 stars
Images
1) Product Images from "Expression of TRPM8 in human reactive lymphoid tissues and mature B-cell neoplasms"
Article Title: Expression of TRPM8 in human reactive lymphoid tissues and mature B-cell neoplasms
Journal: Oncology Letters
doi: 10.3892/ol.2018.9386
Figure Legend Snippet: Immunohistochemistry of TRPM8 and lymphocyte markers in tonsils and mature B-cell neoplasms. (A) The CD23 immunostain recognizes four different zones of a tonsillar lymphoid follicle, namely, the MaZ, outer zone (*), LZ, and DZ. MZ: SYM / MZ ; IF: Interfollicular area (×40). (B) The TRPM8 immunostain in the same lymphoid follicle as (A). There are many TRPM8 + cells in the light zone and SYM/MZ (×40). (C) TRPM8 + cells in the light zone of a tonsillar lymphoid follicle (×200). (D) TRPM8 + cells in SYM/MZ (×400). (E) Double immunostain of IRF4/MUM-1 and TRPM8 in the tonsillar germinal center using digital photomicrographs. The nuclei of IRF4/MUM-1 + cells are shown as blue in a digital photo. The same tissue section was immunostained with TRPM8 and IRF4/MUM-1 + TRPM8 + cells, shown as red in the photo. The first photo was overlaid with the second photo. IRF4/MUM-1 + TRPM8 + cells are recognized as cells having a black-colored nucleus and red-colored cytoplasm (×200). (F) TRPM8 + neoplastic cells in plasma cell myeloma; immunostaining score=4 (×200). (G) TRPM8 + cells in lymphoplasmacytic lymphoma; immunostaining score=2 (×200). (H) TRPM8 + cells in mantle cell lymphoma; immunostaining score=0 (×200). All sections were counterstained with hematoxylin. SYM, lymphoepithelial symbiosis; MZ, marginal zone; TRPM8, transient receptor potential melastatin 8; DZ, dark zonel LZ, light zone; MaZ, mantle zone; IF: Interfollicular area.
Techniques Used: Immunohistochemistry, Immunostaining
Figure Legend Snippet: Frequency of the co-expression of lymphocyte markers on TRPM8-positive cells in the reactive tonsillar germinal center and SYM/marginal zone by double immunostaining.
Techniques Used: Double Immunostaining, Standard Deviation
Figure Legend Snippet: Expression of TRPM8 in mature B-cell neoplasms.
Techniques Used: Expressing
Figure Legend Snippet: Relationship between IPI and TRPM8 scores. A close relationship was found between both scores ( r =−0.598855, P=0.0135). TRPM8, transient receptor potential melastatin 8; IPI, international prognostic index.
Techniques Used:
Figure Legend Snippet: RT-PCR of TRPM8 mRNA in plasma cell myeloma, follicular lymphoma and mantle cell lymphoma. (A) A positive band of 100 bp in length for TRPM8 mRNA was found in two cases of plasma cell myeloma ( M1 & M2 ) using frozen tissue specimens. (B) A positive band of 100 bp in length for TRPM8 mRNA was found in one case of plasma cell myeloma (1–5; n=5), but not in follicular lymphoma (6,7 and 8; n=3) and mantle cell lymphoma (9,10; n=2) using FFPE tissue specimens. ( M ) Molecular markers, ( N ) negative control, ( A ) well-differentiated prostatic carcinoma as a positive control. TRPM8, transient receptor potential melastatin 8; RT-PCR, reverse transcription polymerase chain reaction.
Techniques Used: Reverse Transcription Polymerase Chain Reaction, Negative Control, Positive Control
Figure Legend Snippet: Scheme showing the relationship between normal B-cell differentiation ( left ) and markers including TRPM8 ( right ). Activated B cells, pre-plasmablasts, and plasmablasts in the germinal center are CD20 + CD38 ± CD79a + , CD20 ± CD38 ± CD79a + IRF4/MUM-1 + , and CD38 + CD79a + TACI + IRF4/MUM-1 + , respectively. Further differentiated early and late plasma cells in the extrafollicular area are CD38 + CD79a + CD138 + TACI + IRF4/MUM-1 + and CD38 + CD79a + CD138 + TACI + , respectively. The present study demonstrated that TRPM8 is expressed on cells differentiating from pre-plasmablasts to late plasma cells. TACI (+): 10–30%, (++); 30–50%, (+++); >50% of the co-expression ratio of lymphocyte markers on TRPM8 + cells. Dotted arrows: Often positive. TRPM8, transient receptor potential melastatin 8; CD, cluster of differentiation; MUM, multiple myeloma oncogene; TACI, transmembrane activator and calcium-signal modulating cyclophilin ligand interactor.
Techniques Used: Cell Differentiation, Expressing
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