double-helix microswimmer array  (Double Helix)

Journal: Science Advances

Article Title: 3D printed personalized magnetic micromachines from patient blood–derived biomaterials

doi: 10.1126/sciadv.abh0273

Figure Lengend Snippet: ( A ) A color-coded assignment of the systematically varied laser intensities for the fabrication of albumin microswimmer. ( B ) The structural quality of the 3D printed albumin microswimmers assessed with differential interference contrast (DIC) imaging. ( C ) The length of the microswimmers measured as a function of the applied laser intensity. ( D and E ) DIC and fluorescence images of the 3D printed albumin-based micromachines. ( F ) Fabrication strategy of the mouse plasma micromachines. ( G ) DIC and fluorescence images of the 3D printed plasma and platelet lysate microswimmers.

Article Snippet: We generated a double-helix microswimmer array printed with varying laser intensities in the range of 7.78 × 10 13 to 1.21 × 10 14 W cm −2 ( ).

Techniques: Imaging, Fluorescence, Clinical Proteomics

Journal: Science Advances

Article Title: 3D printed personalized magnetic micromachines from patient blood–derived biomaterials

doi: 10.1126/sciadv.abh0273

Figure Lengend Snippet: Swimming trajectories and step-out frequencies of albumin microswimmers with varying designs: ( A ) A single-helix microswimmer, ( B ) double-helix microswimmer, and ( C ) microroller. The step-out frequencies are determined by stepwise increasing the actuation frequency.

Article Snippet: We generated a double-helix microswimmer array printed with varying laser intensities in the range of 7.78 × 10 13 to 1.21 × 10 14 W cm −2 ( ).

Techniques:

Journal: Science Advances

Article Title: 3D printed personalized magnetic micromachines from patient blood–derived biomaterials

doi: 10.1126/sciadv.abh0273

Figure Lengend Snippet: ( A ) Enzymatic degradation observed under the time-lapse DIC imaging in the presence of trypsin enzyme at a concentration comparable to the pancreatic juice at 37°C. ( B ) An increase in the dimensions of albumin microswimmers during the degradation before the total collapse of the microswimmer fabric. ( C and D ) The biocompatibility of the degradation products of albumin microswimmers assessed by the viability of the exposed haMSCs at 24 hours. (C) Representative calcein acetoxymethyl ester/ethidium homodimer-1–stained fluorescence images of the exposed haMSCs. (D) The viability of the exposed haMSCs assessed based on the quantified intracellular adenosine 5′-triphosphate amount.

Article Snippet: We generated a double-helix microswimmer array printed with varying laser intensities in the range of 7.78 × 10 13 to 1.21 × 10 14 W cm −2 ( ).

Techniques: Imaging, Concentration Assay, Staining, Fluorescence