pcdna3.1 vectors sub-cloned with the whole sequence of dnmt3a (Ribobio co)
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Pcdna3.1 Vectors Sub Cloned With The Whole Sequence Of Dnmt3a, supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dnmt3a+sequence/dnmt1+sirna/pm36376550-32-9-17
Average 90 stars, based on 1 article reviews
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Over Expression:Article Title: DNMT1-Mediated the Downregulation of FOXF1 Promotes High Glucose-induced Podocyte Damage by Regulating the miR-342-3p/E2F1 Axis. Article Snippet: Podocyte damage plays a crucial role in the occurrence and development of diabetic nephropathy (DN).. Accumulating evidence suggests that dysregulation of transcription factors plays a crucial role in podocyte damage in DN.. However, the biological functions and underlying mechanisms of most transcription factors in hyperglycemia-induced podocytes damage remain largely unknown. Negative Control:Article Title: DNMT1-Mediated the Downregulation of FOXF1 Promotes High Glucose-induced Podocyte Damage by Regulating the miR-342-3p/E2F1 Axis. Article Snippet: Podocyte damage plays a crucial role in the occurrence and development of diabetic nephropathy (DN).. Accumulating evidence suggests that dysregulation of transcription factors plays a crucial role in podocyte damage in DN.. However, the biological functions and underlying mechanisms of most transcription factors in hyperglycemia-induced podocytes damage remain largely unknown. Article Title: ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency. Article Snippet: The human immunodeficiency virus type 1 (HIV-1) reservoir consists of latently infected cells which present a major obstacle to achieving a functional cure for HIV-1.. The formation and maintenance of HIV-1 latency have been extensively studied, and latency-reversing agents (LRAs) that can reactivate latent HIV-1 by targeting the involved host factors are developed; however, their clinical efficacies remain unsatisfac tory.. Therefore, it is imperative to identify novel targets for more potential candidates or better combinations for LRAs. other:Article Title: BCL7A inhibits the progression and drug-resistance in acute myeloid leukemia. Article Snippet: Short hairpin RNAs used for the knockdown of DNMT1, DNMT3A, DNMT3B, PTBP1 and IRF7 (sh-DNMT1, shDNMT3A, sh-DNMT3B) and Article Title: DNMT3A facilitates breast cancer progression via regulating ADAMTS8 mediated EGFR-MEK-ERK activation. Article Snippet: DNMT3A resistant small interfering RNAs (si-DNMT3A-1, si-DNMT3A-2, and si-DNMT3A-3, si-ADAMTS8–1, si-ADAMTS8–2, si-ADAMTS8–3, si-NC) were synthesized by Article Title: ETS2 overexpression ameliorates cartilage injury in osteoarthritis by the ETS2/miR-155/STAT1/DNMT1 feedback loop pathway. Article Snippet: Osteoarthritis (OA) is the most common irreversible chronic joint dysfunction disease, which is pathologically characterized by disturbance of articular cartilage homeostasis leading to subsequent inflammatory response and cartilage extracellular matrix (ECM) degradation.. Increasing evidence has demonstrated the dysregulation of transcription factors play crucial roles in the occurrence and development of osteoarthritis (OA), but the potential functions and mechanism of most transcription factors in OA has not been completely illuminated.. In this study, we identified that transcription factor V-ets erythroblastosis virus E26 oncogene homolog 2 (ETS2) was significantly down-regulated in OA cartilage and IL-1β-induced OA chondrocytes. Article Title: Epigenetic PPARγ preservation attenuates temporomandibular joint osteoarthritis. Article Snippet: Objective: Previous studies have demonstrated that PPARγ deficiency is associated with osteoarthritis in the knee joint.. However, whether epigenetic PPARγ dysregulation has any effect on temporomandibular joint osteoarthritis (TMJOA) is unknown.. This study aims to determine the role and mechanism of epigenetic PPARγ dysregulation in TMJOA. Mutagenesis:Article Title: Co-transcriptional R-loops-mediated epigenetic regulation drives growth retardation and docetaxel chemosensitivity enhancement in advanced prostate cancer Article Snippet: .. Antibodies used in this study were: anti-Myc tag (ab32, Abcam), anti-IGF2BP1 (ab290736, Abcam), anti-IGF2BP2 (ab128175, Abcam), anti-IGF2BP3 (ab177477, Abcam), anti-RBM15 (10587-1-AP, Proteintech), anti-DNMT1 (ab92314, Abcam), anti-DNMT3A (ab307503, Abcam), anti-DNMT3B(67,259, Cell Signaling Technology), anti-SEMA3F (SAB2107196, Sigma), anti-S9.6 (MABE1095, Sigma), anti-5-mC (ab214727, Abcam), anti-m 6 A (SAB5600251, Sigma), anti-YAP1(phosphor S127, ab76252, Abcam), anti-YAP1(66900-1-Ig, Proteintech), anti-LATS1(66569-1-Ig, Proteintech), anti-LATS2(20276-1-AP, Proteintech), anti-β-Actin(4970, Cell Signaling Technology). Produced:Article Title: Co-transcriptional R-loops-mediated epigenetic regulation drives growth retardation and docetaxel chemosensitivity enhancement in advanced prostate cancer Article Snippet: .. Antibodies used in this study were: anti-Myc tag (ab32, Abcam), anti-IGF2BP1 (ab290736, Abcam), anti-IGF2BP2 (ab128175, Abcam), anti-IGF2BP3 (ab177477, Abcam), anti-RBM15 (10587-1-AP, Proteintech), anti-DNMT1 (ab92314, Abcam), anti-DNMT3A (ab307503, Abcam), anti-DNMT3B(67,259, Cell Signaling Technology), anti-SEMA3F (SAB2107196, Sigma), anti-S9.6 (MABE1095, Sigma), anti-5-mC (ab214727, Abcam), anti-m 6 A (SAB5600251, Sigma), anti-YAP1(phosphor S127, ab76252, Abcam), anti-YAP1(66900-1-Ig, Proteintech), anti-LATS1(66569-1-Ig, Proteintech), anti-LATS2(20276-1-AP, Proteintech), anti-β-Actin(4970, Cell Signaling Technology). Knockdown:Article Title: ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency. Article Snippet: The human immunodeficiency virus type 1 (HIV-1) reservoir consists of latently infected cells which present a major obstacle to achieving a functional cure for HIV-1.. The formation and maintenance of HIV-1 latency have been extensively studied, and latency-reversing agents (LRAs) that can reactivate latent HIV-1 by targeting the involved host factors are developed; however, their clinical efficacies remain unsatisfac tory.. Therefore, it is imperative to identify novel targets for more potential candidates or better combinations for LRAs. Real-time Polymerase Chain Reaction:Article Title: ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency. Article Snippet: The human immunodeficiency virus type 1 (HIV-1) reservoir consists of latently infected cells which present a major obstacle to achieving a functional cure for HIV-1.. The formation and maintenance of HIV-1 latency have been extensively studied, and latency-reversing agents (LRAs) that can reactivate latent HIV-1 by targeting the involved host factors are developed; however, their clinical efficacies remain unsatisfac tory.. Therefore, it is imperative to identify novel targets for more potential candidates or better combinations for LRAs. Western Blot:Article Title: ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency. Article Snippet: The human immunodeficiency virus type 1 (HIV-1) reservoir consists of latently infected cells which present a major obstacle to achieving a functional cure for HIV-1.. The formation and maintenance of HIV-1 latency have been extensively studied, and latency-reversing agents (LRAs) that can reactivate latent HIV-1 by targeting the involved host factors are developed; however, their clinical efficacies remain unsatisfac tory.. Therefore, it is imperative to identify novel targets for more potential candidates or better combinations for LRAs. Synthesized:Article Title: Integration of RRBS and RNA-seq unravels the regulatory role of DNMT3A in porcine Sertoli cell proliferation Article Snippet: .. Three |
