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Hypogen Inc catalyst version 4.11
Catalyst Version 4.11, supplied by Hypogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/discovery+studios+catalyst+hypogen+algorithm/software+catalyst+hypogen/pmc04632247-316-7-11
Average 90 stars, based on 1 article reviews
catalyst version 4.11 - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Determination and modelling of stereoselective interactions of ligands with drug transporters: A key dimension in the understanding of drug disposition
Article Snippet: The pharmacophore modelling was carried out using Catalyst version 4.11 and HypoGen and was based upon the correlation of chiral structures and experimentally determined K i values determined using 1-methyl-4-phenylpyridinium (MPP + ) as the marker ligand ( Moaddel et al. 2007c ).

Article Title: Poster presentation abstracts
Article Snippet: Poster presentation abstracts Springer Science+Business Media, LLC 2010 Session I (18-02-2010) DESIGN, SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL 1,3,4-THIADIAZOLE DERIVATIVES AS POSSIBLE ANTICONVULSANT AGENTS Abhishek Soni, Sushil.. K. Kashaw Pharmaceutical Chemistry Division, Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar, 470003, MP, India. e-mail: sonipharma@gmail.com 1,3,4-Thiadiazole exhibits various biological activities such as, anti-inflammatory, anticonvulsant, antibacterial, antitubercular, antifungal, anti-viral and antimicrobial activity.. Two novel series A (1–5) N-(5-sulfanyl-1,3,4-thiadiazol-2-yl)hydrazinecarboxamide and B (1–3) 1-(5-sulfanyl-1,3,4-thiadiazol2-yl)urea have been synthesized.

Article Title: Toxin-related antibodies with antimicrobial and antiviral activity
Article Snippet: Pharmacophores can be determined using software such as CATALYST (including HypoGen or HipHop) [56], CERIUS2, or constructed by hand from a known conformation of a polypeptide of the invention.

Article Title: Structure-based hepatitis C virus drug design
Article Snippet: Pharmacophores can be determined using software such as CATALYST (including HypoGen or HipHop) [5], CERIUS2, or constructed by hand from a known conformation of a lead compound.

Article Title: Exploring Enantiospecific Ligand-Protein Interactions Using Cellular Membrane Affinity Chromatography: Chiral Recognition as a Dynamic Process
Article Snippet: The pharmacophore modeling was carried out using Catalyst version 4.11 and HypoGen and was based upon the correlation of the structures and activities (K i values) of the compounds used in the study.

Generated:

Article Title: Advances in the Design and Synthesis of Prazosin Derivatives over the Last Ten Years
Article Snippet: .. Those pharmacophores were generated using the HypoGen algorithm in Catalyst software with the feature options of H-bond acceptor (HBA), H-bond donor (HBD), hydrophobic (aromatic) (Har), hydrophobic (aliphatic) (Hal) and positive ionisable (PI) [ 88 ]. ..

Article Title: Ligand-based and structure-based approaches in identifying ideal pharmacophore against c-Jun N-terminal kinase-3.
Article Snippet: Structure and ligand based pharmacophore modeling and docking studies carried out using diversified set of c-Jun N-terminal kinase-3 (JNK3) inhibitors are presented in this paper.. Ligand based pharmacophore model (LBPM) was developed for 106 inhibitors of JNK3 using a training set of 21 compounds to reveal structural and chemical features necessary for these molecules to inhibit JNK3.. Hypo1 consisted of two hydrogen bond acceptors (HBA), one hydrogen bond donor (HBD), and a hydrophobic (HY) feature with a correlation coefficient (r) of 0.950.

Software:

Article Title: Advances in the Design and Synthesis of Prazosin Derivatives over the Last Ten Years
Article Snippet: .. Those pharmacophores were generated using the HypoGen algorithm in Catalyst software with the feature options of H-bond acceptor (HBA), H-bond donor (HBD), hydrophobic (aromatic) (Har), hydrophobic (aliphatic) (Hal) and positive ionisable (PI) [ 88 ]. ..

Article Title: Molecular modelling and docking studies on heat shock protein 90 (Hsp90) inhibitors.
Article Snippet: Taylor & Francis makes every effort to ensure the accuracy of all the information (the “Content”) contained in the publications on our platform.. However, Taylor & Francis, our agents, and our licensors make no representations or warranties whatsoever as to the accuracy, completeness, or suitability for any purpose of the Content.. Any opinions and views expressed in this publication are the opinions and views of the authors, and are not the views of or endorsed by Taylor & Francis.

Article Title: Ligand-based and structure-based approaches in identifying ideal pharmacophore against c-Jun N-terminal kinase-3.
Article Snippet: Structure and ligand based pharmacophore modeling and docking studies carried out using diversified set of c-Jun N-terminal kinase-3 (JNK3) inhibitors are presented in this paper.. Ligand based pharmacophore model (LBPM) was developed for 106 inhibitors of JNK3 using a training set of 21 compounds to reveal structural and chemical features necessary for these molecules to inhibit JNK3.. Hypo1 consisted of two hydrogen bond acceptors (HBA), one hydrogen bond donor (HBD), and a hydrophobic (HY) feature with a correlation coefficient (r) of 0.950.



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Hypogen Inc discovery studio's catalyst hypogen algorithm
Discovery Studio's Catalyst Hypogen Algorithm, supplied by Hypogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/discovery+studios+catalyst+hypogen+algorithm/discovery+studio+2+5/10__22270_slash_ujpr__v8i5__1008-60-1-4
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