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Diagnostica Stago dedicated software program
Dedicated Software Program, supplied by Diagnostica Stago, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dedicated+software+program/software+thrombinoscope/pmc12062582-54-1-5
Average 86 stars, based on 1 article reviews

dedicated software program - by Bioz Stars, 2026-10

86/100 stars

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Article Title: A murine multiple-injury model for the study of thromboinflammation
Article Snippet: auma Acute Care Surg ume 96, Number 2 eutrophil extracellular traps (NETs) contribute to trauma-induced coagulopathy.. We aimed to develop a murine multiple-injury model that induces thrombo-inflammatory response, that is, NETosis and accelerated thrombin generation.. METHODS: W ild-type male mice (n = 10, aged 8–12 weeks) underwent multiple injuries (gastrocnemius crush, femur fracture, and laparotomy) and were comparedwith an uninjured control group (n = 10).Micewere euthanized by cardiac puncture performed 3 hours after injury.Whole blood sampleswere immediately processed to platelet poor plasma for thrombin generation kinetics (calibrated automated thrombogram), myeloperoxidase (MPO), and von Willebrand factor quantification.

Article Title: Improved Stability of Proline-derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement
Article Snippet: Thrombinoscope (Diagnostica Stago, Parsippany, NJ, USA) TGA was performed using the thrombinoscope software and according to the manufacturer’s instructions.

Article Title: Discovery and optimization of marstacimab, a human monoclonal antibody targeting tissue factor pathway inhibitor for the treatment of hemophilia A and B.
Article Snippet: The ability of purified anti-TFPI antibodies to restore thrombin generation in human hemophilic plasma (with attenuated FVIIIa activity) was assessed in TGA, with TGA reagents Calibrated Automated Thrombogram including the Fluoroskan Ascent fluorescent plate reader (Thrombinoscope BV), and Thrombinoscope software (version 5; Diagnostica Stago) as described previously.9 The thrombin generation reagents, PPP-Reagent LOW (a mixture of 4 μM phospholipids and 1 pM tissue factor), thrombin calibrator, FluCa-kit (comprised Fluo-Buffer and Fluo-Substrate containing the fluorogenic substrate solubilized in dimethyl sulfoxide), were obtained from Diagnostica Stago.

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Article Title: Marstacimab, an antitissue factor pathway inhibitor, combined with bypassing agents: effects on thrombin generation and in hemostatically normal rats
Article Snippet: .. Data generated by the Thrombinscope software (Diagnostica Stago, Parsippany, NJ) was exported to Microsoft Excel (version 2013). ..

Software:

Article Title: Emicizumab, the factor VIII mimetic bispecific monoclonal antibody: effects on thrombin generation and thromboelastometry
Article Snippet: Thrombin generation was continuously recorded with a dedicated fluorimeter (Fluoroskan Ascent; ThermoLabsystem) with a specific fluorogenic substrate (417 μM) (Bachem). .. Thrombinoscope software (Diagnostica Stago) was used to calculate the parameters stemming from the thrombin generation curve. ..