Journal: Molecular Therapy Advances
Article Title: Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates
doi: 10.1016/j.omta.2026.201726
Figure Lengend Snippet: Cytokine expression profile after AAV gene therapy in NHPs Quantification of vitreous cytokines in NHP1 (A) and NHP2 (B) using the LegendPlex NHP Inflammation Panel with levels expressed as fold-change (log 2) in mean fluorescence intensity (MFI) relative to baseline. RE, right eyes; LE, left eye. (C and D) Single-cell transcriptomic analysis of cytokine gene expression among retinal cell types in NHP1 and NHP2, respectively.
Article Snippet: Data were analyzed in the LEGENDplex Data Analysis Software (Qognit, BioLegend).
Techniques: Expressing, Fluorescence, Single Cell, Gene Expression