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Spatial Transcriptomics Inc mouse model ncbi gene expression omnibus gse292392
Mouse Model Ncbi Gene Expression Omnibus Gse292392, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/d+spatial+transcriptomics+gene+expression+analysis/database+expression+gene+geo+omnibus/pmc12490860-669-41-32
Average 86 stars, based on 1 article reviews
mouse model ncbi gene expression omnibus gse292392 - by Bioz Stars, 2026-09
86/100 stars

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Sequencing:

Article Title: Lineage origin and microenvironment shape neuroblastoma transcriptional state and plasticity
Article Snippet: .. The sequencing data generated in this study is deposited in the Gene Expression Omnibus under GSE301974 (scRNA-seq data), GSE301860 (lineage tracing data from scRNA-seq), GSE301869 (spatial transcriptomics data). ..

Generated:

Article Title: Lineage origin and microenvironment shape neuroblastoma transcriptional state and plasticity
Article Snippet: .. The sequencing data generated in this study is deposited in the Gene Expression Omnibus under GSE301974 (scRNA-seq data), GSE301860 (lineage tracing data from scRNA-seq), GSE301869 (spatial transcriptomics data). ..

Article Title: The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia.
Article Snippet: .. This statement should provide the following information, where applicable: - Accession codes, unique identifiers, or web links for publicly available datasets - A description of any restrictions on data availability - For clinical datasets or third party data, please ensure that the statement adheres to our policy Transcriptomic data generated in this study are available at Gene Expression Omnibus (GEO) database under accession numbers GSE297667 (spatial transcriptomics data) and GSE297665 (scRNA-seq data). ..

Article Title: Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
Article Snippet: .. The following datasets were generated: Kramnik I Zhernovkov V Gimelbrant A 2023 Control of macrophage response to TNF by the sst1 locus NCBI Gene Expression Omnibus GSE164698 Kobzik L Kramnik I 2025 Spatial Transcriptomics of Controlled vs Uncontrolled Tuberculosis in a Mouse Model NCBI Gene Expression Omnibus GSE292392 ..

Gene Expression:

Article Title: Lineage origin and microenvironment shape neuroblastoma transcriptional state and plasticity
Article Snippet: .. The sequencing data generated in this study is deposited in the Gene Expression Omnibus under GSE301974 (scRNA-seq data), GSE301860 (lineage tracing data from scRNA-seq), GSE301869 (spatial transcriptomics data). ..

Article Title: The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia.
Article Snippet: .. This statement should provide the following information, where applicable: - Accession codes, unique identifiers, or web links for publicly available datasets - A description of any restrictions on data availability - For clinical datasets or third party data, please ensure that the statement adheres to our policy Transcriptomic data generated in this study are available at Gene Expression Omnibus (GEO) database under accession numbers GSE297667 (spatial transcriptomics data) and GSE297665 (scRNA-seq data). ..

Article Title: The SWI/SNF chromatin-remodeling subunit DPF2 regulates macrophage inflammation in intestinal injury via the CACNA1D-mediated MAPK pathway.
Article Snippet: .. All raw and processed seq uencing data (single- cell RNA- seq, spatial transcriptomics- seq, and ATAC- Seq) has been deposited at the NCBI’s Gene Expression Omnibus (GEO) database [GEO GSE289938 (49), GSE290563 (50), GSE290650 (51)]. ..

Article Title: Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
Article Snippet: .. The following datasets were generated: Kramnik I Zhernovkov V Gimelbrant A 2023 Control of macrophage response to TNF by the sst1 locus NCBI Gene Expression Omnibus GSE164698 Kobzik L Kramnik I 2025 Spatial Transcriptomics of Controlled vs Uncontrolled Tuberculosis in a Mouse Model NCBI Gene Expression Omnibus GSE292392 ..

Spatial Transcriptomics:

Article Title: Lineage origin and microenvironment shape neuroblastoma transcriptional state and plasticity
Article Snippet: .. The sequencing data generated in this study is deposited in the Gene Expression Omnibus under GSE301974 (scRNA-seq data), GSE301860 (lineage tracing data from scRNA-seq), GSE301869 (spatial transcriptomics data). ..

Article Title: The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia.
Article Snippet: .. This statement should provide the following information, where applicable: - Accession codes, unique identifiers, or web links for publicly available datasets - A description of any restrictions on data availability - For clinical datasets or third party data, please ensure that the statement adheres to our policy Transcriptomic data generated in this study are available at Gene Expression Omnibus (GEO) database under accession numbers GSE297667 (spatial transcriptomics data) and GSE297665 (scRNA-seq data). ..

Article Title: Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
Article Snippet: .. The following datasets were generated: Kramnik I Zhernovkov V Gimelbrant A 2023 Control of macrophage response to TNF by the sst1 locus NCBI Gene Expression Omnibus GSE164698 Kobzik L Kramnik I 2025 Spatial Transcriptomics of Controlled vs Uncontrolled Tuberculosis in a Mouse Model NCBI Gene Expression Omnibus GSE292392 ..

RNA Sequencing:

Article Title: The SWI/SNF chromatin-remodeling subunit DPF2 regulates macrophage inflammation in intestinal injury via the CACNA1D-mediated MAPK pathway.
Article Snippet: .. All raw and processed seq uencing data (single- cell RNA- seq, spatial transcriptomics- seq, and ATAC- Seq) has been deposited at the NCBI’s Gene Expression Omnibus (GEO) database [GEO GSE289938 (49), GSE290563 (50), GSE290650 (51)]. ..

Control:

Article Title: Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
Article Snippet: .. The following datasets were generated: Kramnik I Zhernovkov V Gimelbrant A 2023 Control of macrophage response to TNF by the sst1 locus NCBI Gene Expression Omnibus GSE164698 Kobzik L Kramnik I 2025 Spatial Transcriptomics of Controlled vs Uncontrolled Tuberculosis in a Mouse Model NCBI Gene Expression Omnibus GSE292392 ..



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Spatial Transcriptomics Inc d spatial transcriptomics gene expression analysis
a Flow cytometry staining of H226 tumor cells in vitro for CD73 expression. Isotype control (gray), anti-CD73 antibody (pink). b Immunofluorescent micrographs of H226 tumors resected from NCG mice 46 days post-implantation. Nucleated cells (DAPI, blue), hypoxia (Hypoxyprobe, green) and CD73 (pink). Representative images from four individual tumors from 10 to 20 different cutting surfaces. c Quantification of hypoxia in various tumor regions within resected H226 tumors from NCG mice determined by mean fluorescence intensity (MFI) of Hypoxyprobe. Representative image of a resected tumor section; quantification was performed across 6 independent slides (3 tumors per slide from individual mice) with an average of 13.5 regions of interest (ROI) analyzed per slide. d Spatial <t>transcriptomics</t> gene expression analysis from hypoxic regions in ( c ) (white = low hypoxia, light green = medium hypoxia, dark green = high hypoxia). Boxplots show the median (line), interquartile range (box), and whiskers extending to values within 1.5× the IQR. e 2 × 10 6 UTD T cells (white, n = 5 individual mice) or unedited (gray, n = 5 individual mice) and A 2A R-KO (red, n = 5 individual mice) CAR T-cells injected I.V. into H226 tumor-bearing NCG mice. Group average of tumor volumes measured via calipers over time (Two-sided Mann–Whitney t-test, n = group average of individual mice, mean ± SEM, P** = 0.0079, P** = 0.0072). f Cumulative tumor burden, calculated as area under the curve, from ( e ) (Two-sided Mann–Whitney t-test, n = average of individual mice as above, mean ± SD, n.s. = 0.0556, P** = 0.00379). g 2 × 10 6 UTD T cells (white, n = 5 individual mice) or unedited (gray, n = 5 individual mice) and A 2A R-KO (red, n = 5 individual mice) CAR T-cells injected I.V. into A549 tumor-bearing NCG mice. Group average of tumor volumes measured via calipers over time (Graph represents group mean ± SD, P** = 0.0072). h Cumulative tumor burden, calculated as area under the curve, from ( g ). (Two-sided Mann–Whitney t-test, n = average of individual mice as above, mean ± SD, n.s. = 0.490, P** = 0.0037). For all data, symbols and error bars reflect individual biological replicates and group mean ± S.E.M. e – h Mann–Whitney t-test performed to calculate statistical significance, ** P < 0.01, * P < 0.05.
D Spatial Transcriptomics Gene Expression Analysis, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/d+spatial+transcriptomics+gene+expression+analysis/kit+spatial+transcriptomics+visium/pmc12749318-73-33-34
Average 86 stars, based on 1 article reviews
d spatial transcriptomics gene expression analysis - by Bioz Stars, 2026-09
86/100 stars
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a Flow cytometry staining of H226 tumor cells in vitro for CD73 expression. Isotype control (gray), anti-CD73 antibody (pink). b Immunofluorescent micrographs of H226 tumors resected from NCG mice 46 days post-implantation. Nucleated cells (DAPI, blue), hypoxia (Hypoxyprobe, green) and CD73 (pink). Representative images from four individual tumors from 10 to 20 different cutting surfaces. c Quantification of hypoxia in various tumor regions within resected H226 tumors from NCG mice determined by mean fluorescence intensity (MFI) of Hypoxyprobe. Representative image of a resected tumor section; quantification was performed across 6 independent slides (3 tumors per slide from individual mice) with an average of 13.5 regions of interest (ROI) analyzed per slide. d Spatial transcriptomics gene expression analysis from hypoxic regions in ( c ) (white = low hypoxia, light green = medium hypoxia, dark green = high hypoxia). Boxplots show the median (line), interquartile range (box), and whiskers extending to values within 1.5× the IQR. e 2 × 10 6 UTD T cells (white, n = 5 individual mice) or unedited (gray, n = 5 individual mice) and A 2A R-KO (red, n = 5 individual mice) CAR T-cells injected I.V. into H226 tumor-bearing NCG mice. Group average of tumor volumes measured via calipers over time (Two-sided Mann–Whitney t-test, n = group average of individual mice, mean ± SEM, P** = 0.0079, P** = 0.0072). f Cumulative tumor burden, calculated as area under the curve, from ( e ) (Two-sided Mann–Whitney t-test, n = average of individual mice as above, mean ± SD, n.s. = 0.0556, P** = 0.00379). g 2 × 10 6 UTD T cells (white, n = 5 individual mice) or unedited (gray, n = 5 individual mice) and A 2A R-KO (red, n = 5 individual mice) CAR T-cells injected I.V. into A549 tumor-bearing NCG mice. Group average of tumor volumes measured via calipers over time (Graph represents group mean ± SD, P** = 0.0072). h Cumulative tumor burden, calculated as area under the curve, from ( g ). (Two-sided Mann–Whitney t-test, n = average of individual mice as above, mean ± SD, n.s. = 0.490, P** = 0.0037). For all data, symbols and error bars reflect individual biological replicates and group mean ± S.E.M. e – h Mann–Whitney t-test performed to calculate statistical significance, ** P < 0.01, * P < 0.05.

Journal: Nature Communications

Article Title: Multiplex gene-editing strategy to engineer allogeneic EGFR-targeting CAR T-cells with improved efficacy against solid tumors

doi: 10.1038/s41467-025-66737-1

Figure Lengend Snippet: a Flow cytometry staining of H226 tumor cells in vitro for CD73 expression. Isotype control (gray), anti-CD73 antibody (pink). b Immunofluorescent micrographs of H226 tumors resected from NCG mice 46 days post-implantation. Nucleated cells (DAPI, blue), hypoxia (Hypoxyprobe, green) and CD73 (pink). Representative images from four individual tumors from 10 to 20 different cutting surfaces. c Quantification of hypoxia in various tumor regions within resected H226 tumors from NCG mice determined by mean fluorescence intensity (MFI) of Hypoxyprobe. Representative image of a resected tumor section; quantification was performed across 6 independent slides (3 tumors per slide from individual mice) with an average of 13.5 regions of interest (ROI) analyzed per slide. d Spatial transcriptomics gene expression analysis from hypoxic regions in ( c ) (white = low hypoxia, light green = medium hypoxia, dark green = high hypoxia). Boxplots show the median (line), interquartile range (box), and whiskers extending to values within 1.5× the IQR. e 2 × 10 6 UTD T cells (white, n = 5 individual mice) or unedited (gray, n = 5 individual mice) and A 2A R-KO (red, n = 5 individual mice) CAR T-cells injected I.V. into H226 tumor-bearing NCG mice. Group average of tumor volumes measured via calipers over time (Two-sided Mann–Whitney t-test, n = group average of individual mice, mean ± SEM, P** = 0.0079, P** = 0.0072). f Cumulative tumor burden, calculated as area under the curve, from ( e ) (Two-sided Mann–Whitney t-test, n = average of individual mice as above, mean ± SD, n.s. = 0.0556, P** = 0.00379). g 2 × 10 6 UTD T cells (white, n = 5 individual mice) or unedited (gray, n = 5 individual mice) and A 2A R-KO (red, n = 5 individual mice) CAR T-cells injected I.V. into A549 tumor-bearing NCG mice. Group average of tumor volumes measured via calipers over time (Graph represents group mean ± SD, P** = 0.0072). h Cumulative tumor burden, calculated as area under the curve, from ( g ). (Two-sided Mann–Whitney t-test, n = average of individual mice as above, mean ± SD, n.s. = 0.490, P** = 0.0037). For all data, symbols and error bars reflect individual biological replicates and group mean ± S.E.M. e – h Mann–Whitney t-test performed to calculate statistical significance, ** P < 0.01, * P < 0.05.

Article Snippet: Representative image of a resected tumor section; quantification was performed across 6 independent slides (3 tumors per slide from individual mice) with an average of 13.5 regions of interest (ROI) analyzed per slide. d Spatial transcriptomics gene expression analysis from hypoxic regions in ( c ) (white = low hypoxia, light green = medium hypoxia, dark green = high hypoxia).

Techniques: Flow Cytometry, Staining, In Vitro, Expressing, Control, Fluorescence, Gene Expression, Injection, MANN-WHITNEY