single site curve-fitting program (GraphPad Software Inc)
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single site curve-fitting program
Single Site Curve Fitting Program, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/curve+fitting+program/single+site+curve+fitting+program/us07846930-374-6-10
Average 90 stars, based on 1 article reviews
Single Site Curve Fitting Program, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/curve+fitting+program/single+site+curve+fitting+program/us07846930-374-6-10
Average 90 stars, based on 1 article reviews
single site curve-fitting program - by Bioz Stars,
2026-10
90/100 stars
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Concentration Assay:Article Title: Substituted pyridyl amide compounds as modulators of the histamine H Article Snippet: Article Title: Substituted 6-(1-piperazinyl)-pyridazines as 5-HT Article Snippet: Nonspecific binding was defined in the presence of 100 μM Article Title: Diaryl-substituted tetrahydroisoquinolines as histamine H Article Snippet: IC50 values were determined by a single site curve-fitting program ( Article Title: Naphthyridine compounds Article Snippet: IC50 values were determined by a single site curve-fitting program ( Article Title: Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines. Article Snippet: A series of (4-aminobutyn-1-yl)benzylamines were prepared and the SAR around three key areas: (1) the amine attached to the butynyl linker (RRN–); (2) the benzylamine moiety (RRN–); and (3) the point of attachment of the benzylamine group (R1R2N– in the ortho, meta, or para positions) was examined.. One compound, 4-[3-(4-piperidin-1-yl-but-1-ynyl)-benzyl]-morpholine (9s) was chosen for further profiling and found to be a selective histamine H3 antagonist with desirable drug-like properties.. Ex vivo receptor occupancy studies established that 9s does occupy H3 binding sites in the brain of rats after oral administration. Article Title: Cycloalkyloxy- and heterocycloalkyloxypyridine compounds as modulators of the histamine H Article Snippet: Article Title: Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor. Article Snippet: Wake-promoting agents such as modafinil are used in the clinic as adjuncts to antidepressant therapy in order to alleviate lethargy.. The wakepromoting action of histamine H3 receptor antagonists has been evidenced in numerous animal studies.. They may therefore be a viable strategy for use as an antidepressant therapy in conjunction with selective serotonin reuptake inhibitors. Article Title: Hexahydro-pyrrolo-isoquinoline compounds Article Snippet: IC50 values were determined by a single site curve-fitting program ( Inhibition:Article Title: Substituted pyridyl amide compounds as modulators of the histamine H Article Snippet: Article Title: Substituted 6-(1-piperazinyl)-pyridazines as 5-HT Article Snippet: Nonspecific binding was defined in the presence of 100 μM Article Title: Diaryl-substituted tetrahydroisoquinolines as histamine H Article Snippet: IC50 values were determined by a single site curve-fitting program ( Article Title: Naphthyridine compounds Article Snippet: IC50 values were determined by a single site curve-fitting program ( Article Title: Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines. Article Snippet: A series of (4-aminobutyn-1-yl)benzylamines were prepared and the SAR around three key areas: (1) the amine attached to the butynyl linker (RRN–); (2) the benzylamine moiety (RRN–); and (3) the point of attachment of the benzylamine group (R1R2N– in the ortho, meta, or para positions) was examined.. One compound, 4-[3-(4-piperidin-1-yl-but-1-ynyl)-benzyl]-morpholine (9s) was chosen for further profiling and found to be a selective histamine H3 antagonist with desirable drug-like properties.. Ex vivo receptor occupancy studies established that 9s does occupy H3 binding sites in the brain of rats after oral administration. Article Title: Cycloalkyloxy- and heterocycloalkyloxypyridine compounds as modulators of the histamine H Article Snippet: Article Title: Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor. Article Snippet: Wake-promoting agents such as modafinil are used in the clinic as adjuncts to antidepressant therapy in order to alleviate lethargy.. The wakepromoting action of histamine H3 receptor antagonists has been evidenced in numerous animal studies.. They may therefore be a viable strategy for use as an antidepressant therapy in conjunction with selective serotonin reuptake inhibitors. Article Title: Hexahydro-pyrrolo-isoquinoline compounds Article Snippet: IC50 values were determined by a single site curve-fitting program ( Binding Assay:Article Title: Substituted pyridyl amide compounds as modulators of the histamine H Article Snippet: Article Title: Substituted 6-(1-piperazinyl)-pyridazines as 5-HT Article Snippet: Nonspecific binding was defined in the presence of 100 μM Article Title: Diaryl-substituted tetrahydroisoquinolines as histamine H Article Snippet: IC50 values were determined by a single site curve-fitting program ( Article Title: Naphthyridine compounds Article Snippet: IC50 values were determined by a single site curve-fitting program ( Article Title: Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines. Article Snippet: A series of (4-aminobutyn-1-yl)benzylamines were prepared and the SAR around three key areas: (1) the amine attached to the butynyl linker (RRN–); (2) the benzylamine moiety (RRN–); and (3) the point of attachment of the benzylamine group (R1R2N– in the ortho, meta, or para positions) was examined.. One compound, 4-[3-(4-piperidin-1-yl-but-1-ynyl)-benzyl]-morpholine (9s) was chosen for further profiling and found to be a selective histamine H3 antagonist with desirable drug-like properties.. Ex vivo receptor occupancy studies established that 9s does occupy H3 binding sites in the brain of rats after oral administration. Article Title: Cycloalkyloxy- and heterocycloalkyloxypyridine compounds as modulators of the histamine H Article Snippet: Article Title: Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor. Article Snippet: Wake-promoting agents such as modafinil are used in the clinic as adjuncts to antidepressant therapy in order to alleviate lethargy.. The wakepromoting action of histamine H3 receptor antagonists has been evidenced in numerous animal studies.. They may therefore be a viable strategy for use as an antidepressant therapy in conjunction with selective serotonin reuptake inhibitors. Article Title: Hexahydro-pyrrolo-isoquinoline compounds Article Snippet: IC50 values were determined by a single site curve-fitting program ( |