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BBN Software Products Corporation fit function in rs/1
Fit Function In Rs/1, supplied by BBN Software Products Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/computer+program+product/computer+program+in+rs+1/pmc01572092-85-13-14
Average 90 stars, based on 1 article reviews
fit function in rs/1 - by Bioz Stars, 2026-09
90/100 stars

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Concentration Assay:

Article Title: Intraindividual comparison of human radial and internal thoracic arteries in vitro and the effect of preoperative calcium blocker therapy.
Article Snippet: The patency rate of radial artery (RA) conduits is considerably lower than that of internal thoracic artery (ITA) grafts and the evidence suggests that this is due to a clinically suspected higher incidence of vasospasm.. The aim of this study was, therefore, to compare intraindividually the pharmacological reactivity of RA with that of ITA.. Both RA and ITA were taken from the same patients and investigated in parallel.

Article Title: Human internal thoracic arteries from diabetic patients are resistant to endothelial dysfunction.
Article Snippet: The aim of this analysis was to compare vasoreactive properties of internal thoracic arteries (ITA) grafts from diabetic (DM) to those of non-diabetic (ND) patients.. Ring segments of ITA, taken from patients undergoing coronary artery bypass grafting, were suspended in organ bath chambers filled with modified Krebs-Henseleit solution and contractile responses to potassium chloride (KCl), noradrenaline (NA), endothelin-1 (ET-l), and endothelium-dependent relaxant responses to acetylcholine (ACH) were recorded isometrically.. The receptor-mediated agonists NA and ET-1 stimulated ITA from both groups within similar concentration ranges while ITA from DM patients proved to be significantly more sensitive to KCl than ITA from ND.

Article Title: Freezing without surrounding cryomedium preserves the endothelium and its function in human internal mammary arteries.
Article Snippet: Purpose: Cryopreserved human blood vessels may become important tools in bypass surgery.. Optimal cryopreservation of an arterial graft should, therefore, preserve both histological and physiological characteristics of smooth muscle and endothelium comparable to the unfrozen artery.. Methods: Rings from human internal mammary arteries (IMA) were investigated in vitro either unfrozen or after immersion into a cryomedium (RPMI 1640 containing 1.8 M Me2SO and 0.1 M sucrose) and cryostorage with and without surrounding medium.

Derivative Assay:

Article Title: Intraindividual comparison of human radial and internal thoracic arteries in vitro and the effect of preoperative calcium blocker therapy.
Article Snippet: The patency rate of radial artery (RA) conduits is considerably lower than that of internal thoracic artery (ITA) grafts and the evidence suggests that this is due to a clinically suspected higher incidence of vasospasm.. The aim of this study was, therefore, to compare intraindividually the pharmacological reactivity of RA with that of ITA.. Both RA and ITA were taken from the same patients and investigated in parallel.

Article Title: Human internal thoracic arteries from diabetic patients are resistant to endothelial dysfunction.
Article Snippet: The aim of this analysis was to compare vasoreactive properties of internal thoracic arteries (ITA) grafts from diabetic (DM) to those of non-diabetic (ND) patients.. Ring segments of ITA, taken from patients undergoing coronary artery bypass grafting, were suspended in organ bath chambers filled with modified Krebs-Henseleit solution and contractile responses to potassium chloride (KCl), noradrenaline (NA), endothelin-1 (ET-l), and endothelium-dependent relaxant responses to acetylcholine (ACH) were recorded isometrically.. The receptor-mediated agonists NA and ET-1 stimulated ITA from both groups within similar concentration ranges while ITA from DM patients proved to be significantly more sensitive to KCl than ITA from ND.

Article Title: Freezing without surrounding cryomedium preserves the endothelium and its function in human internal mammary arteries.
Article Snippet: Purpose: Cryopreserved human blood vessels may become important tools in bypass surgery.. Optimal cryopreservation of an arterial graft should, therefore, preserve both histological and physiological characteristics of smooth muscle and endothelium comparable to the unfrozen artery.. Methods: Rings from human internal mammary arteries (IMA) were investigated in vitro either unfrozen or after immersion into a cryomedium (RPMI 1640 containing 1.8 M Me2SO and 0.1 M sucrose) and cryostorage with and without surrounding medium.

other:

Article Title: The mechanism of cryoinjury: In vitro studies on human internal mammary arteries
Article Snippet: Computerized analysis of concentration-response curves was performed using the procedure Fit Function in RS/1 (BBN Software Products Corporation, Cambridge, MA, U.S.A.) according to the equation f(x)=A/(1+B/X) where f(x) is the fraction of receptors activated by the agonist concentration X, A represents the maximal response (E max ) and B represents the EC 50 values (concentration of the agonist producing 50% of E max ).

Article Title: Improved endothelial function after a modified harvesting technique of the internal thoracic artery.
Article Snippet: Computerized analysis of concentration-response curves was performed using the procedure Fit Function in RS/1 (BBN Software Products Corporation, Cambridge, MA, USA) according to the equation f(x) 1⁄4 A/(1 þ B/X) where f(x) is the fraction of receptors activated by the agonist concentration X, A represents the maximal response (Emax) and B represents the EC50 values (concentration of the agonist producing 50% of Emax).

Article Title: Activated Rho/Rho kinase and modified calcium sensitivity in cryopreserved human saphenous veins.
Article Snippet: Background: We have shown previously that cryopreservation of human internal mammary arteries activates protein kinase C and enhances intracellular Ca [Ca]i.. We now present evidence that in human saphenous veins (HSV) cryoinjury is associated with activation of the Rho/Rho kinase signaling pathways and enhanced [Ca]i.. Methods: HSV were investigated in vitro either unfrozen within 12 h after removal or after storage at 196 C in a cryomedium containing 1.8 M dimethyl sulfoxide and 0.1 M sucrose as cryoprotectant additives.



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