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Micos GmbH complex subunit mic60
Liver proteins showing differential expression in piglets fed SP and Control diets

Complex Subunit Mic60, supplied by Micos GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/complex+subunit+mic60/complex+subunit+mic60/pmc11539757-211-2-2
Average 90 stars, based on 1 article reviews

complex subunit mic60 - by Bioz Stars, 2026-09

90/100 stars

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1) Product Images from "Metabolomics and proteomics insights into hepatic responses of weaned piglets to dietary Spirulina inclusion and lysozyme supplementation"

Article Title: Metabolomics and proteomics insights into hepatic responses of weaned piglets to dietary Spirulina inclusion and lysozyme supplementation

Journal: BMC Veterinary Research

doi: 10.1186/s12917-024-04339-7

Figure Legend Snippet: Liver proteins showing differential expression in piglets fed SP and Control diets

Techniques Used: Quantitative Proteomics, Control, Binding Assay, Variant Assay

Figure Legend Snippet: Liver proteins showing differential expression in piglets fed SP + L and SP diets

Techniques Used: Quantitative Proteomics

Fluorescence:

Article Title: Compositionally unique mitochondria in filopodia support cellular migration.
Article Snippet: .. METEOR identification and Fluorescence Intensity Ratio quantification Fixed cells were co-immunolabeled as described above with a control MICOS antibody (mouse anti-MIC60 or rabbit anti-MIC19 labeled with a secondary antibody conjugated to Alexa Fluor 488 (AF488)) along with a primary antibody targeting a query protein labeled with a secondary antibody conjugated to Alexa Fluor 555 (AF555). ..

Control:

Labeling:

other:

Article Title: A New Perspective on the Role of Alterations in Mitochondrial Proteins Involved in ATP Synthesis and Mobilization in Cardiomyopathies.
Article Snippet: Additionally, Mic60, the core subunit of the mitochondrial contact site and cristae-organizing system (MICOS) has been shown to interact with PINK1, highlighting its significant role in PD [199].

Article Title: Mitochondrial reactive oxygen species regulate acetyl-CoA flux between cytokine production and fatty acid synthesis in effector T cells.
Article Snippet: 4 Cell Reports 44, 115430, March 25, 2025 TMEM11 deficiency changes mitochondrial inner membrane architecture and respiration The mitochondrial inner membrane cristae organizing system (MICOS) complex, OPA1, and F1F0-ATP synthase (complex V) are essential for cristae formation.26,27 The MICOS complex, consisting of MIC60 and MIC10 sub-complexes, is involved in formation of the cristae junctions.26,27 MIC60 forms the mitochondrial intermembrane bridging complex with proteins at the outer membrane, while MIC10 establishes inner membrane curvature.

Article Title: A New Perspective on the Role of Alterations in Mitochondrial Proteins Involved in ATP Synthesis and Mobilization in Cardiomyopathies.
Article Snippet: The observation that the deletion of Sam50 strongly affects the cristae structure but not the levels of MICOS components [168,187] indicates that this effect on respiratory complexes is likely due to changes in the morphology of the IM, which, in turn, could be related to mtDNA stability, since mutations in Mic14 cause a reduction in the number of mitochondrial nucleoids (nucleoids are associated with the IM, are mediated by MICOS, and contain proteins for the replication and repair of mtDNA).

Article Title: A New Perspective on the Role of Alterations in Mitochondrial Proteins Involved in ATP Synthesis and Mobilization in Cardiomyopathies
Article Snippet: Additionally, Mic60, the core subunit of the mitochondrial contact site and cristae-organizing system (MICOS) has been shown to interact with PINK1, highlighting its significant role in PD [ ].

Article Title: Structures and functions of the MICOS: Pathogenesis and therapeutic implications in Alzheimer's disease
Article Snippet: Moreover, fibroblasts treated with SLC25A46 siRNA exhibit substantial reductions in the protein levels of MIC60 and MIC19 (MIC60 to 34% of control and MIC19 to 21%) , suggesting that SLC25A46 regulates MICOS complex stability.

Article Title: A New Perspective on the Role of Alterations in Mitochondrial Proteins Involved in ATP Synthesis and Mobilization in Cardiomyopathies
Article Snippet: The observation that the deletion of Sam50 strongly affects the cristae structure but not the levels of MICOS components [ , ] indicates that this effect on respiratory complexes is likely due to changes in the morphology of the IM, which, in turn, could be related to mtDNA stability, since mutations in Mic14 cause a reduction in the number of mitochondrial nucleoids (nucleoids are associated with the IM, are mediated by MICOS, and contain proteins for the replication and repair of mtDNA).

Membrane:

Article Title: Identification of key genes regulating brown adipose tissue thermogenesis in goat kids ( Capra hircus ) by using weighted gene co-expression network analysis
Article Snippet: .. The IMMT gene encodes the inner membrane mitochondrial protein MIC60, which, along with MIC19 and MIC25, forms the MIC60 subcomplex of the mitochondrial contact site and cristae organizing system (MICOS), which is crucial for the formation of mitochondrial cristae ( , ). ..

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