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GeneDx Inc array cgh
Array Cgh, supplied by GeneDx Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/complementary+dna+(cdna)+microarray/clinical+microarray+services/10__1159_slash_000124391-912-37-25
Average 90 stars, based on 1 article reviews

array cgh - by Bioz Stars, 2026-11

90/100 stars

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Article Title: A Patient Case of Malan Syndrome Involving 19p13.2 Deletion of NFIX with Longitudinal Follow-Up and Future Prospectives
Article Snippet: Whole-genome array comparative genomic hybridization (CGH) and single-nucleotide polymorphism (SNP) analysis (GeneDx, Gaithersburg, MD) revealed the following: arr [GRCh37] 19p13.2 (13,180,583–13,255,428) × 1 de novo deletion of 75 kb ( ).

Article Title: Heterozygous deletions of noncoding parts of the PRPF31 gene cause retinitis pigmentosa via reduced gene expression
Article Snippet: Genomic DNA samples of MOL0931–1 and MOL0931–2 were tested with array-based comparative genomic hybridization (aCGH) targeted for PRPF31 at GeneDx (Gaithersburg, MD).

Article Title: Novel Intragenic PAX6 Deletion in a Pedigree with Aniridia, Morbid Obesity, and Diabetes
Article Snippet: OMIM #600958) gene, known to be associated with hypertrophic cardiomyopathy. ( 21 – 22 ) The specific breakpoints of this deletion were subsequently shown to encompass a 1.7 Mbp segment of chromosome 11 (46,842,700–48,588,943 bp) using a comparative genome hybridization (CGH) assay (GeneDx, Gaithersburg, MD).

Article Title: Corneal ectasia associated with posterior lamellar opacification.
Article Snippet: Although array comparative genomic hybridization (aCGH) had previously been completed at an outside facility (GeneDx, Gaithersburg, MD, USA) for case 3, realtime quantitative polymerase chain reaction (qPCR) was performed to confirm the absence of any deletions involving one or more of the four SLRP genes in the PACD locus.

Microarray:

Article Title: A retrospective analysis of memantine use in a pediatric neurology clinic.
Article Snippet: Background: Memantine is an N-methyl-D-aspartate receptor (NMDA-R) antagonist, approved for dementia, but also studied in pediatric autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD).. Methods: We reviewed children treated with memantine in a single-centre pediatric neurology clinic.. Clinical data extracted included age, sex, weight, clinical history, reason for memantine prescription, period of treatment trial and dosage, treatment response, side effects, and concomitant medications.

Sequencing:

Hybridization:

Article Title: Hereditary Myoclonus Dystonia: A Novel SGCE Variant and Phenotype Including Intellectual Disability
Article Snippet: .. Owing to the presence of intellectual disability, a whole-genome array comparative genomic hybridization with single-nucleotide polymorphism (SNP) analysis from GeneDx™ was performed and failed to show any abnormalities. .. This test is performed on a custom-designed oligonucleotide microarray (GenomeDx v5) and the design is based on human genome build GRCh37/UCSChg19 and contains approximately 118,000 probes that provide copy number data and 66,000 probes that generate genotype information through analysis of SNPs.

Next-Generation Sequencing:

Article Title: Heterozygous Deletion of Chromosome 15q13.3 in a Boy with Developmental Regression, Global Developmental Delay, Hypotonia, and Short Stature
Article Snippet: .. A whole-genome array of genomic DNA was performed on the patient and his mother (GeneDx, Gaithersburg, MD, USA) using a proprietary capture system developed by GeneDx for next generation sequencing with CNV calling (NGS-CNV). ..