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Sangon Biotech coding sequence of bcl-2
Coding Sequence Of Bcl 2, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/coding+sequence+of+bcl-2/bcl+2+antibody/pmc07840972-277-4-20
Average 90 stars, based on 1 article reviews
coding sequence of bcl-2 - by Bioz Stars, 2026-10
90/100 stars

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Expressing:

Article Title: An ultrasensitive and specific fluorescence split-aptasensor for VEGF 165 detection based on nicking enzyme-assisted 3D DNA walker coupling with CRISPR-Cas12a.
Article Snippet: The overexpression of vascular endothelial growth factor 165 (VEGF165) in cancer cells plays a pivotal role in promoting tumor metastasis by facilitating their excessively rapid proliferation and division.. Hence, the development of analytical methods possessing high sensitivity and resistance to interference is imperative for the detection of VEGF165.. Various types of aptasensors have been devised for VEGF165 detection; however, the performance of these biosensors can be influenced by non-target signals caused by conformational changes in unbound aptamers.

Article Title: Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).
Article Snippet: The aim of this study was to explore the role of the ZnT9 protein in obesity-induced sperm maturation disorders in men.. We generated a mouse model of obesity-induced weak spermatogenesis via a high-fat diet (HFD) for 10 weeks.. In addition to the HFD, a 5-week intervention of salubrinal (SAL) (an inhibitor of endoplasmic reticulum stress) (1 mg/kg/day), ZnSO4 (15 mg/kg/day), and their combination was started at week 6, after which sperm viability and epididymal tissue damage were assessed.

Article Title: Ratiometric electrochemical immunosensor for simultaneous detection of C-myc and Bcl-2 based on multi-role alloy composites.
Article Snippet: A ratiometric electrochemical immunosensor is proposed for simultaneous detection of cellular-myelocytomatosis oncoprotein (C-myc) and B-cell lymphoma 2 (Bcl-2) via the potential-resolved strategy.. It relied on multi-role co-loaded alloy composites (CLACs) and poly(3,4-ethylenedioxythiophene) (PEDOT)-graphene oxide (GO)-multiwalled carbon nanotubes (MWCNTs) (PGM) modified electrodes.. CLACs with good catalytic and enzyme-like properties were synthesized in one step by loading tetramethylbenzidine (TMB) or methylene blue (MB) into Pt-Pd alloy and used as label materials.

Article Title: lncRNA SNHG4 inhibits ferroptosis by orchestrating miR-150-5p/c-Myb axis in colorectal cancer.
Article Snippet: LncRNAs have shown to regulate ferroptosis in colorectal cancer (CRC), but the mechanism remains largely unknown.. This study unveiled the mechanism of SNHG4 underlying ferroptosis in CRC.. RNA-seq and RT-PCR assay confirmed SNHG4 was decreased after Erastin treatment in CRC cells.

Article Title: miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway.
Article Snippet: In addition, pmirGLO-BCL2-wild/mut was purchased from Sangon Biotech (Shanghai, China), while miR181d mimics, mimics NC, miR-181d inhibitor, and inhibitor NC were purchased from GenePharma (Shanghai, China).

Article Title: SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.
Article Snippet: Oxaliplatin resistance poses a significant challenge in colorectal cancer (CRC) therapy, necessitating further investigation into the underlying molecular mechanisms.. This study aimed to elucidate the regulatory role of SNHG4 in oxaliplatin resistance and ferroptosis in CRC.. Our findings revealed that treatment with oxaliplatin led to downregulation of SNHG4 expression in CRC cells, while resistant CRC cells exhibited higher levels of SNHG4 compared to parental cells.

SYBR Green Assay:

Article Title: An ultrasensitive and specific fluorescence split-aptasensor for VEGF 165 detection based on nicking enzyme-assisted 3D DNA walker coupling with CRISPR-Cas12a.
Article Snippet: The overexpression of vascular endothelial growth factor 165 (VEGF165) in cancer cells plays a pivotal role in promoting tumor metastasis by facilitating their excessively rapid proliferation and division.. Hence, the development of analytical methods possessing high sensitivity and resistance to interference is imperative for the detection of VEGF165.. Various types of aptasensors have been devised for VEGF165 detection; however, the performance of these biosensors can be influenced by non-target signals caused by conformational changes in unbound aptamers.

Article Title: Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).
Article Snippet: The aim of this study was to explore the role of the ZnT9 protein in obesity-induced sperm maturation disorders in men.. We generated a mouse model of obesity-induced weak spermatogenesis via a high-fat diet (HFD) for 10 weeks.. In addition to the HFD, a 5-week intervention of salubrinal (SAL) (an inhibitor of endoplasmic reticulum stress) (1 mg/kg/day), ZnSO4 (15 mg/kg/day), and their combination was started at week 6, after which sperm viability and epididymal tissue damage were assessed.

Article Title: Ratiometric electrochemical immunosensor for simultaneous detection of C-myc and Bcl-2 based on multi-role alloy composites.
Article Snippet: A ratiometric electrochemical immunosensor is proposed for simultaneous detection of cellular-myelocytomatosis oncoprotein (C-myc) and B-cell lymphoma 2 (Bcl-2) via the potential-resolved strategy.. It relied on multi-role co-loaded alloy composites (CLACs) and poly(3,4-ethylenedioxythiophene) (PEDOT)-graphene oxide (GO)-multiwalled carbon nanotubes (MWCNTs) (PGM) modified electrodes.. CLACs with good catalytic and enzyme-like properties were synthesized in one step by loading tetramethylbenzidine (TMB) or methylene blue (MB) into Pt-Pd alloy and used as label materials.

Article Title: lncRNA SNHG4 inhibits ferroptosis by orchestrating miR-150-5p/c-Myb axis in colorectal cancer.
Article Snippet: LncRNAs have shown to regulate ferroptosis in colorectal cancer (CRC), but the mechanism remains largely unknown.. This study unveiled the mechanism of SNHG4 underlying ferroptosis in CRC.. RNA-seq and RT-PCR assay confirmed SNHG4 was decreased after Erastin treatment in CRC cells.

Article Title: miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway.
Article Snippet: In addition, pmirGLO-BCL2-wild/mut was purchased from Sangon Biotech (Shanghai, China), while miR181d mimics, mimics NC, miR-181d inhibitor, and inhibitor NC were purchased from GenePharma (Shanghai, China).

Article Title: SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.
Article Snippet: Oxaliplatin resistance poses a significant challenge in colorectal cancer (CRC) therapy, necessitating further investigation into the underlying molecular mechanisms.. This study aimed to elucidate the regulatory role of SNHG4 in oxaliplatin resistance and ferroptosis in CRC.. Our findings revealed that treatment with oxaliplatin led to downregulation of SNHG4 expression in CRC cells, while resistant CRC cells exhibited higher levels of SNHG4 compared to parental cells.

Reverse Transcription:

Article Title: An ultrasensitive and specific fluorescence split-aptasensor for VEGF 165 detection based on nicking enzyme-assisted 3D DNA walker coupling with CRISPR-Cas12a.
Article Snippet: The overexpression of vascular endothelial growth factor 165 (VEGF165) in cancer cells plays a pivotal role in promoting tumor metastasis by facilitating their excessively rapid proliferation and division.. Hence, the development of analytical methods possessing high sensitivity and resistance to interference is imperative for the detection of VEGF165.. Various types of aptasensors have been devised for VEGF165 detection; however, the performance of these biosensors can be influenced by non-target signals caused by conformational changes in unbound aptamers.

Article Title: Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).
Article Snippet: The aim of this study was to explore the role of the ZnT9 protein in obesity-induced sperm maturation disorders in men.. We generated a mouse model of obesity-induced weak spermatogenesis via a high-fat diet (HFD) for 10 weeks.. In addition to the HFD, a 5-week intervention of salubrinal (SAL) (an inhibitor of endoplasmic reticulum stress) (1 mg/kg/day), ZnSO4 (15 mg/kg/day), and their combination was started at week 6, after which sperm viability and epididymal tissue damage were assessed.

Article Title: Ratiometric electrochemical immunosensor for simultaneous detection of C-myc and Bcl-2 based on multi-role alloy composites.
Article Snippet: A ratiometric electrochemical immunosensor is proposed for simultaneous detection of cellular-myelocytomatosis oncoprotein (C-myc) and B-cell lymphoma 2 (Bcl-2) via the potential-resolved strategy.. It relied on multi-role co-loaded alloy composites (CLACs) and poly(3,4-ethylenedioxythiophene) (PEDOT)-graphene oxide (GO)-multiwalled carbon nanotubes (MWCNTs) (PGM) modified electrodes.. CLACs with good catalytic and enzyme-like properties were synthesized in one step by loading tetramethylbenzidine (TMB) or methylene blue (MB) into Pt-Pd alloy and used as label materials.

Article Title: lncRNA SNHG4 inhibits ferroptosis by orchestrating miR-150-5p/c-Myb axis in colorectal cancer.
Article Snippet: LncRNAs have shown to regulate ferroptosis in colorectal cancer (CRC), but the mechanism remains largely unknown.. This study unveiled the mechanism of SNHG4 underlying ferroptosis in CRC.. RNA-seq and RT-PCR assay confirmed SNHG4 was decreased after Erastin treatment in CRC cells.

Article Title: miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway.
Article Snippet: In addition, pmirGLO-BCL2-wild/mut was purchased from Sangon Biotech (Shanghai, China), while miR181d mimics, mimics NC, miR-181d inhibitor, and inhibitor NC were purchased from GenePharma (Shanghai, China).

Article Title: SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.
Article Snippet: Oxaliplatin resistance poses a significant challenge in colorectal cancer (CRC) therapy, necessitating further investigation into the underlying molecular mechanisms.. This study aimed to elucidate the regulatory role of SNHG4 in oxaliplatin resistance and ferroptosis in CRC.. Our findings revealed that treatment with oxaliplatin led to downregulation of SNHG4 expression in CRC cells, while resistant CRC cells exhibited higher levels of SNHG4 compared to parental cells.

Polymerase Chain Reaction:

Article Title: An ultrasensitive and specific fluorescence split-aptasensor for VEGF 165 detection based on nicking enzyme-assisted 3D DNA walker coupling with CRISPR-Cas12a.
Article Snippet: The overexpression of vascular endothelial growth factor 165 (VEGF165) in cancer cells plays a pivotal role in promoting tumor metastasis by facilitating their excessively rapid proliferation and division.. Hence, the development of analytical methods possessing high sensitivity and resistance to interference is imperative for the detection of VEGF165.. Various types of aptasensors have been devised for VEGF165 detection; however, the performance of these biosensors can be influenced by non-target signals caused by conformational changes in unbound aptamers.

Article Title: Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).
Article Snippet: The aim of this study was to explore the role of the ZnT9 protein in obesity-induced sperm maturation disorders in men.. We generated a mouse model of obesity-induced weak spermatogenesis via a high-fat diet (HFD) for 10 weeks.. In addition to the HFD, a 5-week intervention of salubrinal (SAL) (an inhibitor of endoplasmic reticulum stress) (1 mg/kg/day), ZnSO4 (15 mg/kg/day), and their combination was started at week 6, after which sperm viability and epididymal tissue damage were assessed.

Article Title: Ratiometric electrochemical immunosensor for simultaneous detection of C-myc and Bcl-2 based on multi-role alloy composites.
Article Snippet: A ratiometric electrochemical immunosensor is proposed for simultaneous detection of cellular-myelocytomatosis oncoprotein (C-myc) and B-cell lymphoma 2 (Bcl-2) via the potential-resolved strategy.. It relied on multi-role co-loaded alloy composites (CLACs) and poly(3,4-ethylenedioxythiophene) (PEDOT)-graphene oxide (GO)-multiwalled carbon nanotubes (MWCNTs) (PGM) modified electrodes.. CLACs with good catalytic and enzyme-like properties were synthesized in one step by loading tetramethylbenzidine (TMB) or methylene blue (MB) into Pt-Pd alloy and used as label materials.

Article Title: lncRNA SNHG4 inhibits ferroptosis by orchestrating miR-150-5p/c-Myb axis in colorectal cancer.
Article Snippet: LncRNAs have shown to regulate ferroptosis in colorectal cancer (CRC), but the mechanism remains largely unknown.. This study unveiled the mechanism of SNHG4 underlying ferroptosis in CRC.. RNA-seq and RT-PCR assay confirmed SNHG4 was decreased after Erastin treatment in CRC cells.

Article Title: miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway.
Article Snippet: In addition, pmirGLO-BCL2-wild/mut was purchased from Sangon Biotech (Shanghai, China), while miR181d mimics, mimics NC, miR-181d inhibitor, and inhibitor NC were purchased from GenePharma (Shanghai, China).

Article Title: SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.
Article Snippet: Oxaliplatin resistance poses a significant challenge in colorectal cancer (CRC) therapy, necessitating further investigation into the underlying molecular mechanisms.. This study aimed to elucidate the regulatory role of SNHG4 in oxaliplatin resistance and ferroptosis in CRC.. Our findings revealed that treatment with oxaliplatin led to downregulation of SNHG4 expression in CRC cells, while resistant CRC cells exhibited higher levels of SNHG4 compared to parental cells.



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