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Tokyo Chemical Industry closed-loop target-controlled infusion (tci) system
Comparison of <t> Postoperative Recovery </t> Assessment and Intraoperative Awareness in Phase II
Closed Loop Target Controlled Infusion (Tci) System, supplied by Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/closed-loop+systems/target+controlled+infusion+tci/pmc12039841-68-29-34
Average 90 stars, based on 1 article reviews
closed-loop target-controlled infusion (tci) system - by Bioz Stars, 2026-10
90/100 stars

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1) Product Images from "Feasibility of Closed-Loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine: A Randomized Controlled Equivalence Trial"

Article Title: Feasibility of Closed-Loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine: A Randomized Controlled Equivalence Trial

Journal: Drug Design, Development and Therapy

doi: 10.2147/DDDT.S508264

Comparison of  Postoperative Recovery  Assessment and Intraoperative Awareness in Phase II
Figure Legend Snippet: Comparison of Postoperative Recovery Assessment and Intraoperative Awareness in Phase II

Techniques Used: Comparison, Control

Related Articles

Concentration Assay:

Article Title: AReS: A patient simulator to facilitate testing of automated anesthesia.
Article Snippet: In AReS, if the user chooses to turn the Target-Controlled Infusion (TCI) mode on, they must configure it similarly to what they should do on a real-life TCI module.3 This module targets the plasma or effect-site concentration for propofol, remifentanil, and rocuronium.

Article Title: Deep sedation using intranasal dexmedetomidine followed by intravenous propofol for pediatric dental treatment.
Article Snippet: During the oral treatment, continuous target-controlled infusion (TCI) of propofol was administered to maintain a Bispectral index (BIS) of 50–70, ensuring deep sedation.

Article Title: Intraoperative transcranial facial motor evoked potential in vestibular schwannoma reflects short-term post operative facial nerve function.
Article Snippet: Preservation of facial nerve function is extremely important in vestibular schwannoma surgery.. Intraoperative transcranial facial motor evoked potential (Tc-fMEP) monitoring was used, and its accuracy and the correlations of Tc-fMEP results with postoperative facial nerve function at various time points were investigated.. Factors associated with postoperative deterioration of facial nerve function were also examined.

Article Title: Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review
Article Snippet: The widespread use of computerized infusion pumps, particularly Target-Controlled Infusion (TCI) technology, has significantly advanced the development of Total Intravenous Anesthesia (TIVA).

Article Title: A prospective clinical trial predicting the 95% effective concentration of remifentanil for skull pin fixation using haemodynamic and surgical pleth index monitoring
Article Snippet: Anaesthesia was administered via target-controlled infusion (TCI) of remifentanil and propofol and monitored using the SPI and bispectral index (BIS).

Article Title: Ultrasound-guided lateral pterygoid muscle injection for inferior alveolar nerve block in sagittal split ramus osteotomy: a three-case series.
Article Snippet: Specific case details: In all three cases, anesthesia was induced with remifentanil (0.5 μg/kg/min) and propofol using a target-controlled infusion (TCI), followed by rocuronium for nasotracheal intubation.

Article Title: Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients
Article Snippet: Propofol has seen the development of multi-center population PK/PD models, leading to the construction of target-controlled infusion (TCI) systems.13,14 However, the scope of populations in the establishment of remimazolam’s PK/PD models is still narrow, with a notable absence of research involving Chinese surgery patients.

Article Title: Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients
Article Snippet: Propofol has seen the development of multi-center population PK/PD models, leading to the construction of target-controlled infusion (TCI) systems., However, the scope of populations in the establishment of remimazolam’s PK/PD models is still narrow, with a notable absence of research involving Chinese surgery patients.

Clinical Proteomics:

Article Title: AReS: A patient simulator to facilitate testing of automated anesthesia.
Article Snippet: In AReS, if the user chooses to turn the Target-Controlled Infusion (TCI) mode on, they must configure it similarly to what they should do on a real-life TCI module.3 This module targets the plasma or effect-site concentration for propofol, remifentanil, and rocuronium.

Article Title: Deep sedation using intranasal dexmedetomidine followed by intravenous propofol for pediatric dental treatment.
Article Snippet: During the oral treatment, continuous target-controlled infusion (TCI) of propofol was administered to maintain a Bispectral index (BIS) of 50–70, ensuring deep sedation.

Article Title: Intraoperative transcranial facial motor evoked potential in vestibular schwannoma reflects short-term post operative facial nerve function.
Article Snippet: Preservation of facial nerve function is extremely important in vestibular schwannoma surgery.. Intraoperative transcranial facial motor evoked potential (Tc-fMEP) monitoring was used, and its accuracy and the correlations of Tc-fMEP results with postoperative facial nerve function at various time points were investigated.. Factors associated with postoperative deterioration of facial nerve function were also examined.

Article Title: Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review
Article Snippet: The widespread use of computerized infusion pumps, particularly Target-Controlled Infusion (TCI) technology, has significantly advanced the development of Total Intravenous Anesthesia (TIVA).

Article Title: A prospective clinical trial predicting the 95% effective concentration of remifentanil for skull pin fixation using haemodynamic and surgical pleth index monitoring
Article Snippet: Anaesthesia was administered via target-controlled infusion (TCI) of remifentanil and propofol and monitored using the SPI and bispectral index (BIS).

Article Title: Ultrasound-guided lateral pterygoid muscle injection for inferior alveolar nerve block in sagittal split ramus osteotomy: a three-case series.
Article Snippet: Specific case details: In all three cases, anesthesia was induced with remifentanil (0.5 μg/kg/min) and propofol using a target-controlled infusion (TCI), followed by rocuronium for nasotracheal intubation.

Article Title: Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients
Article Snippet: Propofol has seen the development of multi-center population PK/PD models, leading to the construction of target-controlled infusion (TCI) systems.13,14 However, the scope of populations in the establishment of remimazolam’s PK/PD models is still narrow, with a notable absence of research involving Chinese surgery patients.

Article Title: Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients
Article Snippet: Propofol has seen the development of multi-center population PK/PD models, leading to the construction of target-controlled infusion (TCI) systems., However, the scope of populations in the establishment of remimazolam’s PK/PD models is still narrow, with a notable absence of research involving Chinese surgery patients.



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Comparison of  Postoperative Recovery  Assessment and Intraoperative Awareness in Phase II

Journal: Drug Design, Development and Therapy

Article Title: Feasibility of Closed-Loop TCI Based on New EEG Baseline in the Presence of Low Dose of Esketamine: A Randomized Controlled Equivalence Trial

doi: 10.2147/DDDT.S508264

Figure Lengend Snippet: Comparison of Postoperative Recovery Assessment and Intraoperative Awareness in Phase II

Article Snippet: As an adjuvant intravenous anesthetic drug, low dose of esketamine has been demonstrated to better maintain hemodynamic stability, offer analgesic effects , , reduce usage of opioids and promote postoperative recovery., Closed-loop target-controlled infusion (TCI) system can continuously adjust drug infusion rate or effect-site concentration in real-time based on patient’s physiological parameters and drug effects.

Techniques: Comparison, Control