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human circrnas microarray  (Arraystar inc)

 
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    Arraystar inc human circrnas microarray
    Schematic illustration of the effect of circular RNAs <t>(circRNAs)</t> on intracranial aneurysm (IA) rupture. Current evidence strongly suggests a central role for endothelial dysfunction in the initiation and progression of IA. Post-subarachnoid hemorrhage (SAH), several early pathophysiological events can be commonly observed in blood-brain barrier (BBB) components, such as the endothelium (endothelial dysfunction). In results, post- SAH injuries can disrupt the integrity and function of the BBB . Both negative (red cross) and positive (green cross) regulation of circRNAs have been observed in this pathological cascade. The role of circRNAs is based on components: 1) strong role in endothelial cells (ECs) homeostasis; 2) regulation of barrier function and vascular tone; 3) associated with SAH and its complications; 4) correlates with clinical outcomes (Glasgow Coma Scale, the volume of SAH, modified Fisher scale, Hunt-Hess levels, and surgical type; 5) regulators of transcription/translation, sequesters of microRNA (miRNA)/RNA-binding proteins (RBPs), and biomarkers of IA.
    Human Circrnas Microarray, supplied by Arraystar inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/circrna+microarray/pmc10730429-109-6-5?v=Arraystar+inc
    Average 90 stars, based on 1 article reviews
    human circrnas microarray - by Bioz Stars, 2026-08
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    Images

    1) Product Images from "Circular RNAs in intracranial aneurysms: Emerging roles in pathogenesis, diagnosis and therapeutic intervention"

    Article Title: Circular RNAs in intracranial aneurysms: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

    Journal: Non-coding RNA Research

    doi: 10.1016/j.ncrna.2023.11.012

    Schematic illustration of the effect of circular RNAs (circRNAs) on intracranial aneurysm (IA) rupture. Current evidence strongly suggests a central role for endothelial dysfunction in the initiation and progression of IA. Post-subarachnoid hemorrhage (SAH), several early pathophysiological events can be commonly observed in blood-brain barrier (BBB) components, such as the endothelium (endothelial dysfunction). In results, post- SAH injuries can disrupt the integrity and function of the BBB . Both negative (red cross) and positive (green cross) regulation of circRNAs have been observed in this pathological cascade. The role of circRNAs is based on components: 1) strong role in endothelial cells (ECs) homeostasis; 2) regulation of barrier function and vascular tone; 3) associated with SAH and its complications; 4) correlates with clinical outcomes (Glasgow Coma Scale, the volume of SAH, modified Fisher scale, Hunt-Hess levels, and surgical type; 5) regulators of transcription/translation, sequesters of microRNA (miRNA)/RNA-binding proteins (RBPs), and biomarkers of IA.
    Figure Legend Snippet: Schematic illustration of the effect of circular RNAs (circRNAs) on intracranial aneurysm (IA) rupture. Current evidence strongly suggests a central role for endothelial dysfunction in the initiation and progression of IA. Post-subarachnoid hemorrhage (SAH), several early pathophysiological events can be commonly observed in blood-brain barrier (BBB) components, such as the endothelium (endothelial dysfunction). In results, post- SAH injuries can disrupt the integrity and function of the BBB . Both negative (red cross) and positive (green cross) regulation of circRNAs have been observed in this pathological cascade. The role of circRNAs is based on components: 1) strong role in endothelial cells (ECs) homeostasis; 2) regulation of barrier function and vascular tone; 3) associated with SAH and its complications; 4) correlates with clinical outcomes (Glasgow Coma Scale, the volume of SAH, modified Fisher scale, Hunt-Hess levels, and surgical type; 5) regulators of transcription/translation, sequesters of microRNA (miRNA)/RNA-binding proteins (RBPs), and biomarkers of IA.

    Techniques Used: Modification, RNA Binding Assay

    Schematic illustration of circular RNAs (circRNAs) regulation mechanisms underlying vascular smooth muscle cells (VSMCs) phenotypic modulation, oxidative stress, and cell death in intracranial aneurysms (IAs). As can be seen from the figure, circRNAs play a role both in the development and progression of IA and in the inhibition of IA through the control of VSMC. However, some of them exhibit a double effect as circ_FOXO3 and circ_0020397.
    Figure Legend Snippet: Schematic illustration of circular RNAs (circRNAs) regulation mechanisms underlying vascular smooth muscle cells (VSMCs) phenotypic modulation, oxidative stress, and cell death in intracranial aneurysms (IAs). As can be seen from the figure, circRNAs play a role both in the development and progression of IA and in the inhibition of IA through the control of VSMC. However, some of them exhibit a double effect as circ_FOXO3 and circ_0020397.

    Techniques Used: Inhibition

    Benefits of using cell free circular RNAs (circRNAs) as biomarkers.
    Figure Legend Snippet: Benefits of using cell free circular RNAs (circRNAs) as biomarkers.

    Techniques Used:

    The studied cell free circular RNAs (circRNAs) are presented as non-invasive biomarkers in intracranial aneurysms (IAs).
    Figure Legend Snippet: The studied cell free circular RNAs (circRNAs) are presented as non-invasive biomarkers in intracranial aneurysms (IAs).

    Techniques Used:

    Summary information on the role of circular RNAs (circRNAs) in the formation and development of intracranial aneurysms (IAs).
    Figure Legend Snippet: Summary information on the role of circular RNAs (circRNAs) in the formation and development of intracranial aneurysms (IAs).

    Techniques Used: Migration, Transformation Assay



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    Mechanisms of action of cirRNA: (A) CircRNAs have the capability to directly interact with transcription complexes, thereby influencing the expression of parental genes. (B) CircRNAs have the ability to act as miRNA sponges. (C) circRNAs can interact with <t>circRNA</t> binding proteins (cRBPs) modulate their functions. (D) CircRNAs have the ability to encode peptides and proteins.
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    Image Search Results


    Mechanisms of action of cirRNA: (A) CircRNAs have the capability to directly interact with transcription complexes, thereby influencing the expression of parental genes. (B) CircRNAs have the ability to act as miRNA sponges. (C) circRNAs can interact with circRNA binding proteins (cRBPs) modulate their functions. (D) CircRNAs have the ability to encode peptides and proteins.

    Journal: Frontiers in Cellular and Infection Microbiology

    Article Title: Recent progress in tuberculosis diagnosis: insights into blood-based biomarkers and emerging technologies

    doi: 10.3389/fcimb.2025.1567592

    Figure Lengend Snippet: Mechanisms of action of cirRNA: (A) CircRNAs have the capability to directly interact with transcription complexes, thereby influencing the expression of parental genes. (B) CircRNAs have the ability to act as miRNA sponges. (C) circRNAs can interact with circRNA binding proteins (cRBPs) modulate their functions. (D) CircRNAs have the ability to encode peptides and proteins.

    Article Snippet: circRNA , 2018 , hsa_circ_0001953; hsa_circ_0009024 , Plasma , aTB vs HC , Arraystar circRNA Microarray , qRT-PCR , UP , 72.50% , 96.00% , 0.915(p < 0.001) , Preclinical , ( ) .

    Techniques: Expressing, Binding Assay

    Comprehensive ceRNA Interaction Networks and Regulatory Axes in GBM. A circRNA/lncRNA–miRNA–mRNA interaction network, illustrating the competitive binding relationships between ncRNAs and mRNAs. The size and color of the nodes represent the strength of interaction and their centrality within the network, respectively. B Regulatory axis network of circRNAs, illustrating the routes of circRNA-mediated control, from circRNAs to miRNAs and on to their mRNA targets. C Regulatory axis network of lncRNAs, outlining specific pathways of regulation from lncRNAs, through miRNAs, to their mRNA targets (color figure online)

    Journal: Clinical and Experimental Medicine

    Article Title: Integrative analysis of glioblastoma multiforme: the power of non-coding RNAs and hub genes in cancer research

    doi: 10.1007/s10238-025-01677-0

    Figure Lengend Snippet: Comprehensive ceRNA Interaction Networks and Regulatory Axes in GBM. A circRNA/lncRNA–miRNA–mRNA interaction network, illustrating the competitive binding relationships between ncRNAs and mRNAs. The size and color of the nodes represent the strength of interaction and their centrality within the network, respectively. B Regulatory axis network of circRNAs, illustrating the routes of circRNA-mediated control, from circRNAs to miRNAs and on to their mRNA targets. C Regulatory axis network of lncRNAs, outlining specific pathways of regulation from lncRNAs, through miRNAs, to their mRNA targets (color figure online)

    Article Snippet: GSE165926 , circRNA , GPL21825 , Arraystar Human CircRNA microarray , 12/4 , China , 2021.

    Techniques: Binding Assay, Control