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robotic sample changer sc  (BIOSAXS GmbH)

 
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    BIOSAXS GmbH robotic sample changer sc
    Robotic Sample Changer Sc, supplied by BIOSAXS GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/changer/automatic+sample+changer/pm36601945-58-20-15
    Average 90 stars, based on 1 article reviews
    robotic sample changer sc - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Software:

    Article Title: BioSAXS at European Synchrotron Radiation Facility – Extremely Brilliant Source: BM29 with an upgraded source, detector, robot, sample environment, data collection and analysis software
    Article Snippet: BioSAXS at BM29 is highly automated and offers two main experimental modes: BioSAXS via a robotic sample changer (SC); and exploiting online size-exclusion chromatography (SEC), which purifies samples just prior to X-ray exposure (Brennich et al. , 2017 ; Tully et al. , 2021 ).

    Article Title: Structural, Thermodynamic and Enzymatic Characterization of N , N -Diacetylchitobiose Deacetylase from Pyrococcus chitonophagus
    Article Snippet: SAXS measurements on the samples were performed at the P12 BioSAXS beamline of PETRA III, DESY (Hamburg, Germany) [ ] using both a robotic sample changer and a size exclusion chromatography setup (SEC-SAXS).

    Article Title: The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function.
    Article Snippet: Biosaxs Customised Beamline Environment (BsxCUBE) software was used to control the automatic sample changer, in which 30 μl volumes were pipetted automatically into a temperature-controlled quartz cell capillary for automated X-ray data collection [37].

    Article Title: Atomistic Modeling of Scattering Curves for Human IgG1/4 Reveals New Structure-Function Insights
    Article Snippet: Sample volumes of 50 μ L were used in the BioSAXS automatic sample changer.

    Article Title: New data analysis for BioSAXS at the ESRF
    Article Snippet: There are two main experiments performed at the BioSAXS beamline – using the sample changer (referred to as SC) or the inline-chromatography setup (referred to as HPLC since it uses a high-pressure liquid chromatograph).

    Article Title: BioSAXS at European Synchrotron Radiation Facility - Extremely Brilliant Source: BM29 with an upgraded source, detector, robot, sample environment, data collection and analysis software.
    Article Snippet: ISSN 1600-5775 Published under a CC BY 4.0 licence BioSAXS at BM29 is highly automated and offers two main experimental modes: BioSAXS via a robotic sample changer (SC); and exploiting online size-exclusion chromatography (SEC), which purifies samples just prior to X-ray exposure (Brennich et al., 2017; Tully et al., 2021).

    Article Title: Direct structural investigation of pH responsiveness in mRNA lipid nanoparticles: Refining paradigms.
    Article Snippet: Using the BioSAXS automatic sample changer [36], 30 μL of the sample was transferred to a quartz capillary mounted in vacuum, where the sample was exposed 20 times for 0.095 s to the beam.

    Article Title: BioSAXS at European Synchrotron Radiation Facility - Extremely Brilliant Source: BM29 with an upgraded source, detector, robot, sample environment, data collection and analysis software.
    Article Snippet: As already stated, BioSAXS at BM29 is highly automated and offers two main experimental modes: BioSAXS via a robotic sample changer (SC) (Round et al., 2015); and exploiting online size-exclusion chromatography (SEC), which purifies samples just prior to X-ray exposure (Brennich et al., 2017; Tully et al., 2021).

    Control:

    Article Title: BioSAXS at European Synchrotron Radiation Facility – Extremely Brilliant Source: BM29 with an upgraded source, detector, robot, sample environment, data collection and analysis software
    Article Snippet: BioSAXS at BM29 is highly automated and offers two main experimental modes: BioSAXS via a robotic sample changer (SC); and exploiting online size-exclusion chromatography (SEC), which purifies samples just prior to X-ray exposure (Brennich et al. , 2017 ; Tully et al. , 2021 ).

    Article Title: Structural, Thermodynamic and Enzymatic Characterization of N , N -Diacetylchitobiose Deacetylase from Pyrococcus chitonophagus
    Article Snippet: SAXS measurements on the samples were performed at the P12 BioSAXS beamline of PETRA III, DESY (Hamburg, Germany) [ ] using both a robotic sample changer and a size exclusion chromatography setup (SEC-SAXS).

    Article Title: The solution structure of the unbound IgG Fc receptor CD64 resembles its crystal structure: Implications for function.
    Article Snippet: Biosaxs Customised Beamline Environment (BsxCUBE) software was used to control the automatic sample changer, in which 30 μl volumes were pipetted automatically into a temperature-controlled quartz cell capillary for automated X-ray data collection [37].

    Article Title: Atomistic Modeling of Scattering Curves for Human IgG1/4 Reveals New Structure-Function Insights
    Article Snippet: Sample volumes of 50 μ L were used in the BioSAXS automatic sample changer.

    Article Title: New data analysis for BioSAXS at the ESRF
    Article Snippet: There are two main experiments performed at the BioSAXS beamline – using the sample changer (referred to as SC) or the inline-chromatography setup (referred to as HPLC since it uses a high-pressure liquid chromatograph).

    Article Title: BioSAXS at European Synchrotron Radiation Facility - Extremely Brilliant Source: BM29 with an upgraded source, detector, robot, sample environment, data collection and analysis software.
    Article Snippet: ISSN 1600-5775 Published under a CC BY 4.0 licence BioSAXS at BM29 is highly automated and offers two main experimental modes: BioSAXS via a robotic sample changer (SC); and exploiting online size-exclusion chromatography (SEC), which purifies samples just prior to X-ray exposure (Brennich et al., 2017; Tully et al., 2021).

    Article Title: Direct structural investigation of pH responsiveness in mRNA lipid nanoparticles: Refining paradigms.
    Article Snippet: Using the BioSAXS automatic sample changer [36], 30 μL of the sample was transferred to a quartz capillary mounted in vacuum, where the sample was exposed 20 times for 0.095 s to the beam.

    Article Title: BioSAXS at European Synchrotron Radiation Facility - Extremely Brilliant Source: BM29 with an upgraded source, detector, robot, sample environment, data collection and analysis software.
    Article Snippet: As already stated, BioSAXS at BM29 is highly automated and offers two main experimental modes: BioSAXS via a robotic sample changer (SC) (Round et al., 2015); and exploiting online size-exclusion chromatography (SEC), which purifies samples just prior to X-ray exposure (Brennich et al., 2017; Tully et al., 2021).



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    Patch-clamp recording system (A) Overview of the preparation table showing the slicer at the left, two PP beakers on ice containing sucrose solution supplied with 95% O2 and 5% CO2. At the foreground a 80 mm in diameter crystallizing dish containing sucrose solution oxygenated using 95% O2 – 5% CO2 is to receive the brain after resection. Large scissors are to remove the head and small scissors to open the skull with a caudal to nasal cut. (B) Schematic representation of the sequential cuts to prepare hemispheres. View of a mouse brain from the top. The cerebral cortex is in grey, the cerebellum in yellow and the hippocampal region in green. A first cut (1) using a scalpel is to remove the cerebellum. A second sagittal cut (2) is to separate both hemispheres. A third (3) and a fourth (4) cut are to remove a small piece of tissue at the lateral side of the hemispheres. The lateral side of the hemisphere is glued on the specimen disk. Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (C) View of the medial side of the two hemispheres in a Petri dish after sagittal cut of the whole brain. The base of the Petri dish is filled with hardened agarose. Brain tissue is lying on the agarose layer and surrounded by liquid-solid sludgy sucrose solution. Inset shows an enlarged view of the hemispheres. (D) View of the top of a mouse brain hemisphere. The brain is in gray and the hippocampus (HPC) in green. Parasagittal slices are cut starting from the medial side of the hemisphere towards the lateral side. Red dashed lines represent consecutive cuts to produce 300 μm thick slices containing the dorsal hippocampus (dorsal HPC). Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (E) Cutting of brain slices in the parasagittal plane using the vibratome. View of the buffer tray containing sucrose solution with a liquid phase close to the hemispheres and a liquid-solid sludgy phase at the border of the buffer tray. (F) Magnified view of the buffer tray. Hemispheres are glued on a specimen disk. The specimen disk contains a magnet in order to be maintained at the bottom of the buffer tray. Inset shows a scheme representing a blade cutting sagittal slices. The brain is in gray and the hippocampus in green. The scheme was created in Biorender. (G) Overview of the water bath containing the storage chamber enclosing the brain slices. Tissue is maintained at a temperature of 34°C. (H) Top view of a storage chamber filled with sucrose solution. A gauze net maintains slices at ∼half-height of the beaker. A small micro filter candle supplies 95% O2 and 5% CO2 gas mixture to the solution. Very small gas bubbles are delivered by micro filter candles with a porosity of 4 corresponding to small pores. (I) Front view of the patch-clamp setup. The microscope is mounted on a table allowing movement in the two horizontal X-Y directions. Manipulators to move pipette are left and right to the recording table. An <t>optical</t> <t>4-time</t> filter changer (Luigs&Neumann) containing magnification glasses is mounted on the top of the microscope and the digital camera (not appearing in the overview) on top of optic changer. (J) Recording chamber containing a brain slice. A water immersion objective (40X) is on top of the slice to visualize neurons. At the right a patch pipette in a pipette holder (Luigs&Neumann) with a bracket (Luigs&Neumann) surrounding the pipette holder to stabilize pipette. Inset shows the stainless steel slice hold-down flat frame with threads (Warner Instruments).
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    Bruker Corporation changer bruker samplejet
    Patch-clamp recording system (A) Overview of the preparation table showing the slicer at the left, two PP beakers on ice containing sucrose solution supplied with 95% O2 and 5% CO2. At the foreground a 80 mm in diameter crystallizing dish containing sucrose solution oxygenated using 95% O2 – 5% CO2 is to receive the brain after resection. Large scissors are to remove the head and small scissors to open the skull with a caudal to nasal cut. (B) Schematic representation of the sequential cuts to prepare hemispheres. View of a mouse brain from the top. The cerebral cortex is in grey, the cerebellum in yellow and the hippocampal region in green. A first cut (1) using a scalpel is to remove the cerebellum. A second sagittal cut (2) is to separate both hemispheres. A third (3) and a fourth (4) cut are to remove a small piece of tissue at the lateral side of the hemispheres. The lateral side of the hemisphere is glued on the specimen disk. Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (C) View of the medial side of the two hemispheres in a Petri dish after sagittal cut of the whole brain. The base of the Petri dish is filled with hardened agarose. Brain tissue is lying on the agarose layer and surrounded by liquid-solid sludgy sucrose solution. Inset shows an enlarged view of the hemispheres. (D) View of the top of a mouse brain hemisphere. The brain is in gray and the hippocampus (HPC) in green. Parasagittal slices are cut starting from the medial side of the hemisphere towards the lateral side. Red dashed lines represent consecutive cuts to produce 300 μm thick slices containing the dorsal hippocampus (dorsal HPC). Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (E) Cutting of brain slices in the parasagittal plane using the vibratome. View of the buffer tray containing sucrose solution with a liquid phase close to the hemispheres and a liquid-solid sludgy phase at the border of the buffer tray. (F) Magnified view of the buffer tray. Hemispheres are glued on a specimen disk. The specimen disk contains a magnet in order to be maintained at the bottom of the buffer tray. Inset shows a scheme representing a blade cutting sagittal slices. The brain is in gray and the hippocampus in green. The scheme was created in Biorender. (G) Overview of the water bath containing the storage chamber enclosing the brain slices. Tissue is maintained at a temperature of 34°C. (H) Top view of a storage chamber filled with sucrose solution. A gauze net maintains slices at ∼half-height of the beaker. A small micro filter candle supplies 95% O2 and 5% CO2 gas mixture to the solution. Very small gas bubbles are delivered by micro filter candles with a porosity of 4 corresponding to small pores. (I) Front view of the patch-clamp setup. The microscope is mounted on a table allowing movement in the two horizontal X-Y directions. Manipulators to move pipette are left and right to the recording table. An <t>optical</t> <t>4-time</t> filter changer (Luigs&Neumann) containing magnification glasses is mounted on the top of the microscope and the digital camera (not appearing in the overview) on top of optic changer. (J) Recording chamber containing a brain slice. A water immersion objective (40X) is on top of the slice to visualize neurons. At the right a patch pipette in a pipette holder (Luigs&Neumann) with a bracket (Luigs&Neumann) surrounding the pipette holder to stabilize pipette. Inset shows the stainless steel slice hold-down flat frame with threads (Warner Instruments).
    Changer Bruker Samplejet, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    sample jet sample changer  (Bruker Corporation)
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    Patch-clamp recording system (A) Overview of the preparation table showing the slicer at the left, two PP beakers on ice containing sucrose solution supplied with 95% O2 and 5% CO2. At the foreground a 80 mm in diameter crystallizing dish containing sucrose solution oxygenated using 95% O2 – 5% CO2 is to receive the brain after resection. Large scissors are to remove the head and small scissors to open the skull with a caudal to nasal cut. (B) Schematic representation of the sequential cuts to prepare hemispheres. View of a mouse brain from the top. The cerebral cortex is in grey, the cerebellum in yellow and the hippocampal region in green. A first cut (1) using a scalpel is to remove the cerebellum. A second sagittal cut (2) is to separate both hemispheres. A third (3) and a fourth (4) cut are to remove a small piece of tissue at the lateral side of the hemispheres. The lateral side of the hemisphere is glued on the specimen disk. Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (C) View of the medial side of the two hemispheres in a Petri dish after sagittal cut of the whole brain. The base of the Petri dish is filled with hardened agarose. Brain tissue is lying on the agarose layer and surrounded by liquid-solid sludgy sucrose solution. Inset shows an enlarged view of the hemispheres. (D) View of the top of a mouse brain hemisphere. The brain is in gray and the hippocampus (HPC) in green. Parasagittal slices are cut starting from the medial side of the hemisphere towards the lateral side. Red dashed lines represent consecutive cuts to produce 300 μm thick slices containing the dorsal hippocampus (dorsal HPC). Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (E) Cutting of brain slices in the parasagittal plane using the vibratome. View of the buffer tray containing sucrose solution with a liquid phase close to the hemispheres and a liquid-solid sludgy phase at the border of the buffer tray. (F) Magnified view of the buffer tray. Hemispheres are glued on a specimen disk. The specimen disk contains a magnet in order to be maintained at the bottom of the buffer tray. Inset shows a scheme representing a blade cutting sagittal slices. The brain is in gray and the hippocampus in green. The scheme was created in Biorender. (G) Overview of the water bath containing the storage chamber enclosing the brain slices. Tissue is maintained at a temperature of 34°C. (H) Top view of a storage chamber filled with sucrose solution. A gauze net maintains slices at ∼half-height of the beaker. A small micro filter candle supplies 95% O2 and 5% CO2 gas mixture to the solution. Very small gas bubbles are delivered by micro filter candles with a porosity of 4 corresponding to small pores. (I) Front view of the patch-clamp setup. The microscope is mounted on a table allowing movement in the two horizontal X-Y directions. Manipulators to move pipette are left and right to the recording table. An <t>optical</t> <t>4-time</t> filter changer (Luigs&Neumann) containing magnification glasses is mounted on the top of the microscope and the digital camera (not appearing in the overview) on top of optic changer. (J) Recording chamber containing a brain slice. A water immersion objective (40X) is on top of the slice to visualize neurons. At the right a patch pipette in a pipette holder (Luigs&Neumann) with a bracket (Luigs&Neumann) surrounding the pipette holder to stabilize pipette. Inset shows the stainless steel slice hold-down flat frame with threads (Warner Instruments).
    Sample Jet Sample Changer, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/changer/SampleJet/pmc12420700-39-10-14
    Average 97 stars, based on 1 article reviews
    sample jet sample changer - by Bioz Stars, 2026-10
    97/100 stars
    		  Buy from Supplier

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    Patch-clamp recording system (A) Overview of the preparation table showing the slicer at the left, two PP beakers on ice containing sucrose solution supplied with 95% O2 and 5% CO2. At the foreground a 80 mm in diameter crystallizing dish containing sucrose solution oxygenated using 95% O2 – 5% CO2 is to receive the brain after resection. Large scissors are to remove the head and small scissors to open the skull with a caudal to nasal cut. (B) Schematic representation of the sequential cuts to prepare hemispheres. View of a mouse brain from the top. The cerebral cortex is in grey, the cerebellum in yellow and the hippocampal region in green. A first cut (1) using a scalpel is to remove the cerebellum. A second sagittal cut (2) is to separate both hemispheres. A third (3) and a fourth (4) cut are to remove a small piece of tissue at the lateral side of the hemispheres. The lateral side of the hemisphere is glued on the specimen disk. Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (C) View of the medial side of the two hemispheres in a Petri dish after sagittal cut of the whole brain. The base of the Petri dish is filled with hardened agarose. Brain tissue is lying on the agarose layer and surrounded by liquid-solid sludgy sucrose solution. Inset shows an enlarged view of the hemispheres. (D) View of the top of a mouse brain hemisphere. The brain is in gray and the hippocampus (HPC) in green. Parasagittal slices are cut starting from the medial side of the hemisphere towards the lateral side. Red dashed lines represent consecutive cuts to produce 300 μm thick slices containing the dorsal hippocampus (dorsal HPC). Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (E) Cutting of brain slices in the parasagittal plane using the vibratome. View of the buffer tray containing sucrose solution with a liquid phase close to the hemispheres and a liquid-solid sludgy phase at the border of the buffer tray. (F) Magnified view of the buffer tray. Hemispheres are glued on a specimen disk. The specimen disk contains a magnet in order to be maintained at the bottom of the buffer tray. Inset shows a scheme representing a blade cutting sagittal slices. The brain is in gray and the hippocampus in green. The scheme was created in Biorender. (G) Overview of the water bath containing the storage chamber enclosing the brain slices. Tissue is maintained at a temperature of 34°C. (H) Top view of a storage chamber filled with sucrose solution. A gauze net maintains slices at ∼half-height of the beaker. A small micro filter candle supplies 95% O2 and 5% CO2 gas mixture to the solution. Very small gas bubbles are delivered by micro filter candles with a porosity of 4 corresponding to small pores. (I) Front view of the patch-clamp setup. The microscope is mounted on a table allowing movement in the two horizontal X-Y directions. Manipulators to move pipette are left and right to the recording table. An optical 4-time filter changer (Luigs&Neumann) containing magnification glasses is mounted on the top of the microscope and the digital camera (not appearing in the overview) on top of optic changer. (J) Recording chamber containing a brain slice. A water immersion objective (40X) is on top of the slice to visualize neurons. At the right a patch pipette in a pipette holder (Luigs&Neumann) with a bracket (Luigs&Neumann) surrounding the pipette holder to stabilize pipette. Inset shows the stainless steel slice hold-down flat frame with threads (Warner Instruments).

    Journal: STAR Protocols

    Article Title: Protocol for whole-cell patch-clamp recording and post hoc identification of hippocampal CA2 pyramidal neurons in adult mouse brain slices

    doi: 10.1016/j.xpro.2026.104470

    Figure Lengend Snippet: Patch-clamp recording system (A) Overview of the preparation table showing the slicer at the left, two PP beakers on ice containing sucrose solution supplied with 95% O2 and 5% CO2. At the foreground a 80 mm in diameter crystallizing dish containing sucrose solution oxygenated using 95% O2 – 5% CO2 is to receive the brain after resection. Large scissors are to remove the head and small scissors to open the skull with a caudal to nasal cut. (B) Schematic representation of the sequential cuts to prepare hemispheres. View of a mouse brain from the top. The cerebral cortex is in grey, the cerebellum in yellow and the hippocampal region in green. A first cut (1) using a scalpel is to remove the cerebellum. A second sagittal cut (2) is to separate both hemispheres. A third (3) and a fourth (4) cut are to remove a small piece of tissue at the lateral side of the hemispheres. The lateral side of the hemisphere is glued on the specimen disk. Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (C) View of the medial side of the two hemispheres in a Petri dish after sagittal cut of the whole brain. The base of the Petri dish is filled with hardened agarose. Brain tissue is lying on the agarose layer and surrounded by liquid-solid sludgy sucrose solution. Inset shows an enlarged view of the hemispheres. (D) View of the top of a mouse brain hemisphere. The brain is in gray and the hippocampus (HPC) in green. Parasagittal slices are cut starting from the medial side of the hemisphere towards the lateral side. Red dashed lines represent consecutive cuts to produce 300 μm thick slices containing the dorsal hippocampus (dorsal HPC). Three-dimensional structure of adult mouse from Brain Explorer 2 (version 2.3.5 Built 2393, Allen institute, https://brain-map.org ). (E) Cutting of brain slices in the parasagittal plane using the vibratome. View of the buffer tray containing sucrose solution with a liquid phase close to the hemispheres and a liquid-solid sludgy phase at the border of the buffer tray. (F) Magnified view of the buffer tray. Hemispheres are glued on a specimen disk. The specimen disk contains a magnet in order to be maintained at the bottom of the buffer tray. Inset shows a scheme representing a blade cutting sagittal slices. The brain is in gray and the hippocampus in green. The scheme was created in Biorender. (G) Overview of the water bath containing the storage chamber enclosing the brain slices. Tissue is maintained at a temperature of 34°C. (H) Top view of a storage chamber filled with sucrose solution. A gauze net maintains slices at ∼half-height of the beaker. A small micro filter candle supplies 95% O2 and 5% CO2 gas mixture to the solution. Very small gas bubbles are delivered by micro filter candles with a porosity of 4 corresponding to small pores. (I) Front view of the patch-clamp setup. The microscope is mounted on a table allowing movement in the two horizontal X-Y directions. Manipulators to move pipette are left and right to the recording table. An optical 4-time filter changer (Luigs&Neumann) containing magnification glasses is mounted on the top of the microscope and the digital camera (not appearing in the overview) on top of optic changer. (J) Recording chamber containing a brain slice. A water immersion objective (40X) is on top of the slice to visualize neurons. At the right a patch pipette in a pipette holder (Luigs&Neumann) with a bracket (Luigs&Neumann) surrounding the pipette holder to stabilize pipette. Inset shows the stainless steel slice hold-down flat frame with threads (Warner Instruments).

    Article Snippet: 4-time filter changer , Luigs&Neumann , Cat#200-100 200 0159-10.

    Techniques: Patch Clamp, Microscopy, Transferring, Slice Preparation