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Spatial Transcriptomics Inc cell
Cell, supplied by Spatial Transcriptomics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cell+spatial+transcriptomic+profiling/cell+single/pmc12720420-317-10-0
Average 86 stars, based on 1 article reviews
cell - by Bioz Stars, 2026-10
86/100 stars

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Article Title: A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types.
Article Snippet: We leveraged single-cell and spatial transcriptomics technologies to develop a high-resolution, spatially resolved atlas of the mouse PVH region.

Article Title: Immunological mechanisms underlying fibrotic diseases via single-cell technologies
Article Snippet: In a study that analyzed both the fibrotic progression and resolution phases of the bleomycin model using single-cell and spatial transcriptomics , CSMD1 + fibroblasts with ECM-secreting properties were induced during the progression phase, whereas CD248 + fibroblasts with tissue repair-promoting properties were induced during the resolution phase ( ).

Article Title: Advancing Cardiovascular Research With Single-Cell and Spatial Transcriptomics
Article Snippet: Single-cell and spatial transcriptomics technologies have transformed the landscape of cardiovascular research, leading to novel insights into cellular heterogeneity and tissue architecture in health and disease.. These technologies enable researchers to deconvolute complex tissues and map gene expression patterns within their spatial contexts, providing critical information on the interplay between cell types and pathways affecting tissue regeneration or progression to fibrosis.. This review presents an overview of the recently developed applications of single-cell and spatial transcriptomics methods and their impact on cardiovascular research.

Construct:

Article Title: Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets
Article Snippet: .. To overcome these challenges, researchers have developed cutting‐edge tools, including: (1) high‐resolution spatial multiomics platforms (e.g., integrated spatial transcriptomics‐proteomics) for spatiotemporal mapping of neuro‐immune interactions to construct comprehensive “neuro‐immune connectomes”; (2) optimized organoid coculture systems, particularly brain–immune cell interaction models; and (3) advanced in vivo imaging techniques (e.g., two‐photon microscopy coupled with specific reporter systems) for real‐time observation of neuro‐immune processes. ..

In Vivo Imaging:

Article Title: Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets
Article Snippet: .. To overcome these challenges, researchers have developed cutting‐edge tools, including: (1) high‐resolution spatial multiomics platforms (e.g., integrated spatial transcriptomics‐proteomics) for spatiotemporal mapping of neuro‐immune interactions to construct comprehensive “neuro‐immune connectomes”; (2) optimized organoid coculture systems, particularly brain–immune cell interaction models; and (3) advanced in vivo imaging techniques (e.g., two‐photon microscopy coupled with specific reporter systems) for real‐time observation of neuro‐immune processes. ..

Microscopy:

Article Title: Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets
Article Snippet: .. To overcome these challenges, researchers have developed cutting‐edge tools, including: (1) high‐resolution spatial multiomics platforms (e.g., integrated spatial transcriptomics‐proteomics) for spatiotemporal mapping of neuro‐immune interactions to construct comprehensive “neuro‐immune connectomes”; (2) optimized organoid coculture systems, particularly brain–immune cell interaction models; and (3) advanced in vivo imaging techniques (e.g., two‐photon microscopy coupled with specific reporter systems) for real‐time observation of neuro‐immune processes. ..

Single Cell:

Article Title: Co-localization analysis of spatial transcriptomics in ligand-receptor pairs from tumor microenvironment.
Article Snippet: Ligand-receptor pair analysis, a key aspect of cell-to-cell interactions, is vital for understanding physiological and pathological processes in organisms.. However, most analytical tools fail to incorporate spatial in situ information, resulting in false positive predictions.. Spatial transcriptomics, which integrates gene expression data with cellular localization, has emerged as a powerful method for inferring cell-cell interactions.

Article Title: Immunometabolic reprogramming of macrophages: Emerging roles in skeletal muscle regeneration and therapeutic perspectives.
Article Snippet: .. Recent advances in single-cell and spatial transcriptomics technologies have revealed the remarkable heterogeneity of macrophage subpopulations within skeletal muscle. ..

Transcriptomics:

Article Title: Co-localization analysis of spatial transcriptomics in ligand-receptor pairs from tumor microenvironment.
Article Snippet: Ligand-receptor pair analysis, a key aspect of cell-to-cell interactions, is vital for understanding physiological and pathological processes in organisms.. However, most analytical tools fail to incorporate spatial in situ information, resulting in false positive predictions.. Spatial transcriptomics, which integrates gene expression data with cellular localization, has emerged as a powerful method for inferring cell-cell interactions.

Cell Characterization:

Article Title: Ontogeny of the spinal cord dorsal horn.
Article Snippet: INTRODUCTION: In every part of our bodies, cell types and anatomy are organized to carry out specialized functions, and the dorsal horn of the mammalian spinal cord serves as a prime example.. It is characterized by a vast array of cell types arranged in a layered microcircuit architecture, with each layer receiving a specific set of sensory and descending neural inputs and contributing in a distinctive manner to animal behavior.. In this way, the dorsal horn represents a common motif of neural organization found throughout the animal kingdom, from the vertebrate midbrain to the fly’s optic lobe.

Article Title: Ontogeny of the spinal cord dorsal horn
Article Snippet: .. For EdU cell count coordinates (and later also for spatial transcriptomics cell coordinates), cell coordinates were normalized so that statistics and graphics could be produced systematically on cell coordinates across sections and experimental groups. ..

Spatial Transcriptomics:

Article Title: Ontogeny of the spinal cord dorsal horn.
Article Snippet: INTRODUCTION: In every part of our bodies, cell types and anatomy are organized to carry out specialized functions, and the dorsal horn of the mammalian spinal cord serves as a prime example.. It is characterized by a vast array of cell types arranged in a layered microcircuit architecture, with each layer receiving a specific set of sensory and descending neural inputs and contributing in a distinctive manner to animal behavior.. In this way, the dorsal horn represents a common motif of neural organization found throughout the animal kingdom, from the vertebrate midbrain to the fly’s optic lobe.

Article Title: Immunometabolic reprogramming of macrophages: Emerging roles in skeletal muscle regeneration and therapeutic perspectives.
Article Snippet: .. Recent advances in single-cell and spatial transcriptomics technologies have revealed the remarkable heterogeneity of macrophage subpopulations within skeletal muscle. ..

Article Title: Ontogeny of the spinal cord dorsal horn
Article Snippet: .. For EdU cell count coordinates (and later also for spatial transcriptomics cell coordinates), cell coordinates were normalized so that statistics and graphics could be produced systematically on cell coordinates across sections and experimental groups. ..

Produced:

Article Title: Ontogeny of the spinal cord dorsal horn.
Article Snippet: INTRODUCTION: In every part of our bodies, cell types and anatomy are organized to carry out specialized functions, and the dorsal horn of the mammalian spinal cord serves as a prime example.. It is characterized by a vast array of cell types arranged in a layered microcircuit architecture, with each layer receiving a specific set of sensory and descending neural inputs and contributing in a distinctive manner to animal behavior.. In this way, the dorsal horn represents a common motif of neural organization found throughout the animal kingdom, from the vertebrate midbrain to the fly’s optic lobe.

Article Title: Ontogeny of the spinal cord dorsal horn
Article Snippet: .. For EdU cell count coordinates (and later also for spatial transcriptomics cell coordinates), cell coordinates were normalized so that statistics and graphics could be produced systematically on cell coordinates across sections and experimental groups. ..



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Comparisons of different single-cell transcriptomic techniques.
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Comparisons of different single-cell transcriptomic techniques.

Journal: Frontiers in Neural Circuits

Article Title: Recent advances in understanding neuronal diversity and neural circuit complexity across different brain regions using single-cell sequencing

doi: 10.3389/fncir.2023.1007755

Figure Lengend Snippet: Comparisons of different single-cell transcriptomic techniques.

Article Snippet: Single-cell transcriptome profiling technology (spatial transcriptomics) , Single cell level , MERFISH , Currently up to 500 selected genes , All cell types , Fresh frozen, PFA-fixed frozen tissue, paraffin-embedded tissue.

Techniques: RNA Sequencing, Formalin-fixed Paraffin-Embedded

Neuronal diversity across different brain regions revealed by single-cell transcriptomic studies. Most recent literature about neuronal transcriptomes have investigated neuron subpopulations from prefrontal cortex, hippocampus, and hypothalamus. Relevant details have been also described in . IT, intratelencephalic-projecting neurons; ET, extratelencephalic-projecting neurons; NP, near-projecting neurons; CT, corticothalamic projecting neurons.

Journal: Frontiers in Neural Circuits

Article Title: Recent advances in understanding neuronal diversity and neural circuit complexity across different brain regions using single-cell sequencing

doi: 10.3389/fncir.2023.1007755

Figure Lengend Snippet: Neuronal diversity across different brain regions revealed by single-cell transcriptomic studies. Most recent literature about neuronal transcriptomes have investigated neuron subpopulations from prefrontal cortex, hippocampus, and hypothalamus. Relevant details have been also described in . IT, intratelencephalic-projecting neurons; ET, extratelencephalic-projecting neurons; NP, near-projecting neurons; CT, corticothalamic projecting neurons.

Article Snippet: Single-cell transcriptome profiling technology (spatial transcriptomics) , Single cell level , MERFISH , Currently up to 500 selected genes , All cell types , Fresh frozen, PFA-fixed frozen tissue, paraffin-embedded tissue.

Techniques: