Review

wm3618f (Rockland Immunochemicals)

Rockland Immunochemicals is a verified supplier

About

News

Press Release

Team

Advisors

Partners

Contact

Bioz Stars

Bioz vStars

Buy from Supplier

Structured Review

Rockland Immunochemicals wm3618f

A OCR of UM001 treated with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), or the combination (PD0325901 + palbociclib) (n=3). B as A, but <t>WM3618F</t> cells were utilized. C Incucyte analysis of UM001 and WM3618F cell lines treated with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), OxPhosi (IACS-010759, 50 nM), MEKi + CDK4/6i (combo), or MEKi + CDK4/6i + OxPhosi (combo + OxPhosi) (*p=0.05, **p<0.005) (n=3). D Percentage annexin-V positive cells following treatment of UM001 and WM3618F with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), OxPhosi (IACS-010759, 50 nM), MEKi + CDK4/6i (combo), or MEKi + CDK4/6i + OxPhosi (combo + OxPhosi) for 48 hours (*p=0.05) (n=3).

Wm3618f, supplied by Rockland Immunochemicals, used in various techniques. Bioz Stars score: 93/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cell+pellets/WM3618F+Non-Viable+Cell+Pellet/pmc07415561-52-0-4
Average 93 stars, based on 3 article reviews

wm3618f - by Bioz Stars, 2026-11

93/100 stars

Images

1) Product Images from "Metabolic adaptations to MEK and CDK4/6 co-targeting in uveal melanoma"

Article Title: Metabolic adaptations to MEK and CDK4/6 co-targeting in uveal melanoma

Journal: Molecular cancer therapeutics

doi: 10.1158/1535-7163.MCT-19-1016

A OCR of UM001 treated with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), or the combination (PD0325901 + palbociclib) (n=3). B as A, but WM3618F cells were utilized. C Incucyte analysis of UM001 and WM3618F cell lines treated with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), OxPhosi (IACS-010759, 50 nM), MEKi + CDK4/6i (combo), or MEKi + CDK4/6i + OxPhosi (combo + OxPhosi) (*p=0.05, **p<0.005) (n=3). D Percentage annexin-V positive cells following treatment of UM001 and WM3618F with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), OxPhosi (IACS-010759, 50 nM), MEKi + CDK4/6i (combo), or MEKi + CDK4/6i + OxPhosi (combo + OxPhosi) for 48 hours (*p=0.05) (n=3).

Figure Legend Snippet: A OCR of UM001 treated with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), or the combination (PD0325901 + palbociclib) (n=3). B as A, but WM3618F cells were utilized. C Incucyte analysis of UM001 and WM3618F cell lines treated with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), OxPhosi (IACS-010759, 50 nM), MEKi + CDK4/6i (combo), or MEKi + CDK4/6i + OxPhosi (combo + OxPhosi) (*p=0.05, **p<0.005) (n=3). D Percentage annexin-V positive cells following treatment of UM001 and WM3618F with control (DMSO), MEKi (PD0325901, 5 nM), CDK4/6i (palbociclib, 0.5 μM), OxPhosi (IACS-010759, 50 nM), MEKi + CDK4/6i (combo), or MEKi + CDK4/6i + OxPhosi (combo + OxPhosi) for 48 hours (*p=0.05) (n=3).

Techniques Used:

Cell Culture:

Article Title: Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma
Article Snippet: Before 16 hours of treatment end, 10 μM EdU was added and then cells processed using the Click-iTTM Plus EdU Alexa FluorTM 594 flow cytometry assay kit (Life Technologies, Carlsbad, CA) based on company protocol. .. WM3618F was purchased from Rockland Immunochemicals (Limerick, PA) and cultured routinely in 1× MCDB media containing 10% heat-inactivated FBS, CaCl 2 , 50 IU penicillin and 50 μg/mL streptomycin. .. The glycolysis stress test kit (#103020-100) was purchased from Agilent (Santa Clara, CA) and the concentration of injection compounds was glucose (10 mM), oligomycin (1 μM) and 2-DG (50 mM).

Review

wm3618f (Rockland Immunochemicals)

Structured Review

Images

1) Product Images from "Metabolic adaptations to MEK and CDK4/6 co-targeting in uveal melanoma"

Related Articles

Cell Culture:

Similar Products

Image Search Results