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pathway-specific cdna microarray chip inflammatory and autoimmune gearray  (SuperArray Bioscience Corporation)

 
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    Structured Review

    SuperArray Bioscience Corporation pathway-specific cdna microarray chip inflammatory and autoimmune gearray
    Scatter plot analysis of gene expression profiling on uveitis patients demonstrates differential gene expression. <t>cDNA</t> <t>microarray</t> analysis on 50 RNA samples from uveitis patients and 1 pooled sample from controls was performed. After normalization on house-keeping genes, e.g, GAPDH and beta-2-microglobulin (B2M), the final scores of each of the genes of all arrays were compared to those from the control array. The scatter plot was acquired as described in the Materials and Methods. The Y-axis represents log scores from uveitis patients (group 2) and the X-axis represents log scores from normal controls (group 1). Each symbol represents one gene with red-colored ones represent 2-fold higher expressed in uveitis patients (group 2), green-colored ones represent 2-fold lower expressed in uveitis patients and the black-colored ones represent within 2-fold cut-off threshold.
    Pathway Specific Cdna Microarray Chip Inflammatory And Autoimmune Gearray, supplied by SuperArray Bioscience Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cdna+microarray+chip/pmc02631441-140-5-13?v=SuperArray+Bioscience+Corporation
    Average 90 stars, based on 1 article reviews
    pathway-specific cdna microarray chip inflammatory and autoimmune gearray - by Bioz Stars, 2026-07
    90/100 stars

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    1) Product Images from "Gene expression profiling in autoimmune non-infectious uveitis disease"

    Article Title: Gene expression profiling in autoimmune non-infectious uveitis disease

    Journal:

    doi:

    Scatter plot analysis of gene expression profiling on uveitis patients demonstrates differential gene expression. cDNA microarray analysis on 50 RNA samples from uveitis patients and 1 pooled sample from controls was performed. After normalization on house-keeping genes, e.g, GAPDH and beta-2-microglobulin (B2M), the final scores of each of the genes of all arrays were compared to those from the control array. The scatter plot was acquired as described in the Materials and Methods. The Y-axis represents log scores from uveitis patients (group 2) and the X-axis represents log scores from normal controls (group 1). Each symbol represents one gene with red-colored ones represent 2-fold higher expressed in uveitis patients (group 2), green-colored ones represent 2-fold lower expressed in uveitis patients and the black-colored ones represent within 2-fold cut-off threshold.
    Figure Legend Snippet: Scatter plot analysis of gene expression profiling on uveitis patients demonstrates differential gene expression. cDNA microarray analysis on 50 RNA samples from uveitis patients and 1 pooled sample from controls was performed. After normalization on house-keeping genes, e.g, GAPDH and beta-2-microglobulin (B2M), the final scores of each of the genes of all arrays were compared to those from the control array. The scatter plot was acquired as described in the Materials and Methods. The Y-axis represents log scores from uveitis patients (group 2) and the X-axis represents log scores from normal controls (group 1). Each symbol represents one gene with red-colored ones represent 2-fold higher expressed in uveitis patients (group 2), green-colored ones represent 2-fold lower expressed in uveitis patients and the black-colored ones represent within 2-fold cut-off threshold.

    Techniques Used: Gene Expression, Microarray, Control

    Clustergram analysis of gene expression revealed 4 distinct gene expression profiles. cDNA microarray was performed as described above and clustergram analysis on microarray data was described in the Materials & Methods section. X-axis represents all genes listed in the cDNA microarray chip and Y-axis depicts gene expression profiles from all samples of uveitis patients normalized on normal controls. Each colored band represents expression of a single gene from one patient when compared to that from normal donors with higher expression in red and lower expression in green. Groups I, II, III and IV designate 4 sub-groups of gene expression profiles. Analysis of gene expression profiling among uveitis patients revealed 4 sets of genes designated as molecular signatures A, B, C and D that can be used to define the 4 sub-groups of gene expression profiles.
    Figure Legend Snippet: Clustergram analysis of gene expression revealed 4 distinct gene expression profiles. cDNA microarray was performed as described above and clustergram analysis on microarray data was described in the Materials & Methods section. X-axis represents all genes listed in the cDNA microarray chip and Y-axis depicts gene expression profiles from all samples of uveitis patients normalized on normal controls. Each colored band represents expression of a single gene from one patient when compared to that from normal donors with higher expression in red and lower expression in green. Groups I, II, III and IV designate 4 sub-groups of gene expression profiles. Analysis of gene expression profiling among uveitis patients revealed 4 sets of genes designated as molecular signatures A, B, C and D that can be used to define the 4 sub-groups of gene expression profiles.

    Techniques Used: Gene Expression, Microarray, Expressing

    Comparison of clustergram analysis of gene expression profiling of 2 male siblings (designated as patient A and patient B) with the same diagnosis of intermediate uveitis with that from normal controls (designated as NL). The cDNA microarray and clustergram analysis were performed as described above and in the Materials and Methods. The X-axis listed all the gene symbols in the cDNA microarray chips. The gene expression profiles from the 2 male siblings with the same diagnosis of intermediate uveitis (designated as patient A and patient B) were aligned with the profile from normal subjects (NL). As described above, each colored band represents expression of a single gene from either patient A or patient B or from normal subjects after normalization on house keeping genes, with higher expression in red and lower expression in green.
    Figure Legend Snippet: Comparison of clustergram analysis of gene expression profiling of 2 male siblings (designated as patient A and patient B) with the same diagnosis of intermediate uveitis with that from normal controls (designated as NL). The cDNA microarray and clustergram analysis were performed as described above and in the Materials and Methods. The X-axis listed all the gene symbols in the cDNA microarray chips. The gene expression profiles from the 2 male siblings with the same diagnosis of intermediate uveitis (designated as patient A and patient B) were aligned with the profile from normal subjects (NL). As described above, each colored band represents expression of a single gene from either patient A or patient B or from normal subjects after normalization on house keeping genes, with higher expression in red and lower expression in green.

    Techniques Used: Comparison, Gene Expression, Biomarker Discovery, Microarray, Expressing



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    Image Search Results


    Gene Expression in the Pituitary Gland of Anxa5 -/- Mice

    Journal: Journal of the Endocrine Society

    Article Title: Augmentation of Nr4a3 and Suppression of Fshb Expression in the Pituitary Gland of Female Annexin A5 Null Mouse

    doi: 10.1210/jendso/bvaa096

    Figure Lengend Snippet: Gene Expression in the Pituitary Gland of Anxa5 -/- Mice

    Article Snippet: Gene chip analysis and cDNA microarray data were carried out at GeneticLab Co., Ltd. (Sapporo, Japan).

    Techniques: Gene Expression, Membrane, Binding Assay

    VERIFICATION OF GENE ARRAY RESULTS BY REAL-TIME QUANTITATIVE PCR ANALYSIS

    Journal: Gene Expression

    Article Title: Distinct Gene Expression Profile of Human Mesenchymal Stem Cells in Comparison to Skin Fibroblasts Employing cDNA Microarray Analysis of 9600 Genes

    doi:

    Figure Lengend Snippet: VERIFICATION OF GENE ARRAY RESULTS BY REAL-TIME QUANTITATIVE PCR ANALYSIS

    Article Snippet: Bone sialoprotein is known as initiator of matrix mineralization and is upregulated during the mineralization phase of osteoblast differentiation ( 27 ). cDNA Microarray We employed a custom-made cDNA microarry chip that was constructed at the Institute for Molecular Biology and Tumor Research Marburg as described previously ( 8 ).

    Techniques: Real-time Polymerase Chain Reaction, Gene Expression, Binding Assay