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CDN Isotopes d4-gcdca
D4 Gcdca, supplied by CDN Isotopes, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cdca/d4+cdca/pmc05089630-92-60-66
Average 90 stars, based on 1 article reviews
d4-gcdca - by Bioz Stars, 2026-11
90/100 stars

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Article Title: Chronic exposure to ambient traffic-related air pollution (TRAP) alters gut microbial abundance and bile acid metabolism in a transgenic rat model of Alzheimer’s disease
Article Snippet: Deuterated internal standards (IS) used included: d4-DCA (CDN Isotopes; CAS No: 112076–61–6), d4-CDCA (CDN Isotopes; CAS No: 99102–69–9), d4-CA (TRC, Canada; Cat no #: C432603), d4-GCDCA (Iso Sciences, CAS No: 1201918–16–2) and d4-LCA (PubChem CID of LCA: 9903, Steraloids).

Article Title: Dried blood spot-based newborn screening for bile acid synthesis disorders, Zellweger spectrum disorder, and Niemann-Pick type C1 by detection of bile acid metabolites.
Article Snippet: Objective: To examine whether it is possible to screen for bile acid synthesis disorders (BASDs) including peroxisome biogenesis disorder 1a (PBD1A) and Niemann-Pick type C1 (NPC1) at the time of newborn mass screening by measuring the intermediary metabolites of bile acid (BA) synthesis.. Methods: Patients with 3β-hydroxy-ΔSuchy et al. (2021)-C27-steroid dehydrogenase/isomerase (HSD3B7) deficiency (n = 2), 3-oxo-ΔPandak and Kakiyama (n.d.)4-steroid 5β-reductase (SRD5B1) deficiency (n = 1), oxysterol 7α-hydroxylase (CYP7B1) deficiency (n = 1), PBD1A (n = 1), and NPC1 (n = 2) with available dried blood spot (DBS) samples collected in the neonatal period were included.. DBSs from healthy neonates at 4 days of age (n = 1055) were also collected for the control.

Article Title: Changes in conjugated urinary bile acids across age groups.
Article Snippet: Standard products such as CA, CDCA, UDCA, DCA, LCA, HCA, GCA, GCDCA, GUDCA, GDCA, GLCA, GHCA, TCA, TCDCA, TUDCA, TDCA, TLCA, and THCA were purchased from Sigma Chemicals (St. Louis, MO), while [2,2,4,4-d4]-CA (d4-CA, internal standard (IS) for unconjugated bile acids), [2,2,4,4-d4]-GCA (d4-GCA, IS for glycine-conjugated bile acids), and [2,2,4,4-d4]-TCA (d4-TCA, IS for T conjugated and double-conjugated bile acids) were obtained from CDN Isotopes (Quebec, Canada).

Article Title: Thermoneutrality or standard temperature: is there an ideal housing temperature to study the antisteatotic effects of green tea in obese mice?
Article Snippet: Metabolic-associated fatty liver disease (MAFLD) is a condition characterized by excessive accumulation of triglycerides in hepatocytes, currently considered the number one cause of chronic liver disease.. MAFLD is strongly associated with obesity, type 2 diabetes, hyperlipidaemia, and hypertension.. Emphasis has been placed on the use of green tea (GT), produced from the Camellia sinensis plant, rich in antioxidants as polyphenols and catechins, on obesity and MAFLD treatment/prevention.

Article Title: Further evidence for blood-to-brain influx of unconjugated bile acids by passive diffusion: Determination of their brain-to-serum concentration ratios in rats by LC/MS/MS.
Article Snippet: [2,2,4,4-2H4]-CA (d4-CA), [2,2,4,4-2H4]-CDCA (d4-CDCA) and [2,2,4,4-2H4]-LCA (d4-LCA) were obtained from CDN Isotopes (Quebec, Canada) and used as the internal standards (ISs).



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