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Sony cd182 apc (clone 5e8/cxcr2) antibody
CD marker expression for individual neutrophil subpopulations. Cell surface expression of neutrophil markers on different neutrophil subpopulations at TP1, including (A) CD16, (B) CD62L, (C) CD66b, (D) CD11b, (E) CD10, (F) CD181, and (G) <t>CD182.</t> CD16 low CD62L low neutrophils exhibit low expression of all analyzed markers. Decreased expression of CD10 and CD11b on banded neutrophils (BN). Data were non-normally distributed (Shapiro-Wilk test), and statistical analysis was conducted using the Kruskal-Wallis test with Dunn’s correction for multiple comparisons (all vs. all); *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. Sample size CD16, CD62L CD66b and CD11b: TP1: N = 33 Non-SIRS patients, 16 SIRS patients; CD10: TP1: N = 32 Non-SIRS patients, 9 SIRS patients; CD181: TP1: N = 39 Non-SIRS patients, 11 SIRS patients; CD182: TP1: N = 31 Non-SIRS patients, 12 SIRS patients.
Cd182 Apc (Clone 5e8/Cxcr2) Antibody, supplied by Sony, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cd182/cd182+apc++clone+5e8+cxcr2++antibody/pmc12280902-76-7-18
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cd182 apc (clone 5e8/cxcr2) antibody - by Bioz Stars, 2026-09
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1) Product Images from "Pro-inflammatory role of neutrophils populations in trauma patients: monitoring neutrophil populations"

Article Title: Pro-inflammatory role of neutrophils populations in trauma patients: monitoring neutrophil populations

Journal: Frontiers in Immunology

doi: 10.3389/fimmu.2025.1565606

CD marker expression for individual neutrophil subpopulations. Cell surface expression of neutrophil markers on different neutrophil subpopulations at TP1, including (A) CD16, (B) CD62L, (C) CD66b, (D) CD11b, (E) CD10, (F) CD181, and (G) CD182. CD16 low CD62L low neutrophils exhibit low expression of all analyzed markers. Decreased expression of CD10 and CD11b on banded neutrophils (BN). Data were non-normally distributed (Shapiro-Wilk test), and statistical analysis was conducted using the Kruskal-Wallis test with Dunn’s correction for multiple comparisons (all vs. all); *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. Sample size CD16, CD62L CD66b and CD11b: TP1: N = 33 Non-SIRS patients, 16 SIRS patients; CD10: TP1: N = 32 Non-SIRS patients, 9 SIRS patients; CD181: TP1: N = 39 Non-SIRS patients, 11 SIRS patients; CD182: TP1: N = 31 Non-SIRS patients, 12 SIRS patients.
Figure Legend Snippet: CD marker expression for individual neutrophil subpopulations. Cell surface expression of neutrophil markers on different neutrophil subpopulations at TP1, including (A) CD16, (B) CD62L, (C) CD66b, (D) CD11b, (E) CD10, (F) CD181, and (G) CD182. CD16 low CD62L low neutrophils exhibit low expression of all analyzed markers. Decreased expression of CD10 and CD11b on banded neutrophils (BN). Data were non-normally distributed (Shapiro-Wilk test), and statistical analysis was conducted using the Kruskal-Wallis test with Dunn’s correction for multiple comparisons (all vs. all); *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. Sample size CD16, CD62L CD66b and CD11b: TP1: N = 33 Non-SIRS patients, 16 SIRS patients; CD10: TP1: N = 32 Non-SIRS patients, 9 SIRS patients; CD181: TP1: N = 39 Non-SIRS patients, 11 SIRS patients; CD182: TP1: N = 31 Non-SIRS patients, 12 SIRS patients.

Techniques Used: Marker, Expressing

Related Articles

Marker:

Article Title: Pro-inflammatory role of neutrophils populations in trauma patients: monitoring neutrophil populations
Article Snippet: Additional antibodies included CD181 APC (clone 8F1/CXCR1), CD182 APC (clone 5E8/CXCR2), and CD66b Alexa Fluor 700 (clone 10F5; Sony Biotechnology, San Jose, CA, USA).

Expressing:

Article Title: Pro-inflammatory role of neutrophils populations in trauma patients: monitoring neutrophil populations
Article Snippet: Additional antibodies included CD181 APC (clone 8F1/CXCR1), CD182 APC (clone 5E8/CXCR2), and CD66b Alexa Fluor 700 (clone 10F5; Sony Biotechnology, San Jose, CA, USA).



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Identification of the key genes expression in external datasets. A IFIT5, IFI16, TRIM22, IFI44L, IRF9, OAS3, BST2, CASP1, CXCR2 were statistically significant in AF expression profile ( GSE41177 ). B IFIT5、CASP1 and CXCR2 were statistically significant in COPD expression profile ( GSE56766 ). C - D ROC of IFIT5、CASP1 and CXCR2 in the AF( GSE79768 ) dataset. -, not significant.;*, p <0.05; **, p <0.01; ***, p < 0.001

Journal: BMC Medical Genomics

Article Title: Shared molecular signatures between atrial fibrillation and chronic obstructive pulmonary disease: an integrated bioinformatic analysis with experimental validation

doi: 10.1186/s12920-026-02335-4

Figure Lengend Snippet: Identification of the key genes expression in external datasets. A IFIT5, IFI16, TRIM22, IFI44L, IRF9, OAS3, BST2, CASP1, CXCR2 were statistically significant in AF expression profile ( GSE41177 ). B IFIT5、CASP1 and CXCR2 were statistically significant in COPD expression profile ( GSE56766 ). C - D ROC of IFIT5、CASP1 and CXCR2 in the AF( GSE79768 ) dataset. -, not significant.;*, p <0.05; **, p <0.01; ***, p < 0.001

Article Snippet: Proteins were then transferred onto the membranes using a constant current of 400 mA for 0.5 h. Following transfer, the membranes were incubated overnight at 4 °C with primary antibodies specific for CASP1 (WL03450, Wanleibio), CXCR2 (bs-1629R, Bioss), IFIT5 (CAP4911, Cohesionbio), and GAPDH (10494-1-AP, Proteintech), ensuring specific detection of target proteins.

Techniques: Expressing

Validation of CASP1, CXCR2, and IFIT5 expression in different clinical groups at mRNA and protein levels. A – C Relative mRNA expression levels of CASP1, IFIT5, and CXCR2 were assessed by qRT-PCR in peripheral blood samples from healthy controls (CON), atrial fibrillation (AF), chronic obstructive pulmonary disease (COPD), and AF combined with COPD (AF+COPD). D – F Quantification of CASP1, IFIT5, and CXCR2 protein expression levels based on Western blot analysis. Signal intensities were normalized to GAPDH. G – I Serum protein concentrations of CASP1 (pmol/L), IFIT5 (pg/mL), and CXCR2 (ng/mL) measured by ELISA in the four groups. J Representative Western blot images for CASP1, IFIT5, and CXCR2 with GAPDH as loading control. *, p < 0.05; **, p <0.01; ***, p < 0.001

Journal: BMC Medical Genomics

Article Title: Shared molecular signatures between atrial fibrillation and chronic obstructive pulmonary disease: an integrated bioinformatic analysis with experimental validation

doi: 10.1186/s12920-026-02335-4

Figure Lengend Snippet: Validation of CASP1, CXCR2, and IFIT5 expression in different clinical groups at mRNA and protein levels. A – C Relative mRNA expression levels of CASP1, IFIT5, and CXCR2 were assessed by qRT-PCR in peripheral blood samples from healthy controls (CON), atrial fibrillation (AF), chronic obstructive pulmonary disease (COPD), and AF combined with COPD (AF+COPD). D – F Quantification of CASP1, IFIT5, and CXCR2 protein expression levels based on Western blot analysis. Signal intensities were normalized to GAPDH. G – I Serum protein concentrations of CASP1 (pmol/L), IFIT5 (pg/mL), and CXCR2 (ng/mL) measured by ELISA in the four groups. J Representative Western blot images for CASP1, IFIT5, and CXCR2 with GAPDH as loading control. *, p < 0.05; **, p <0.01; ***, p < 0.001

Article Snippet: Proteins were then transferred onto the membranes using a constant current of 400 mA for 0.5 h. Following transfer, the membranes were incubated overnight at 4 °C with primary antibodies specific for CASP1 (WL03450, Wanleibio), CXCR2 (bs-1629R, Bioss), IFIT5 (CAP4911, Cohesionbio), and GAPDH (10494-1-AP, Proteintech), ensuring specific detection of target proteins.

Techniques: Biomarker Discovery, Expressing, Quantitative RT-PCR, Western Blot, Enzyme-linked Immunosorbent Assay, Control

A Transcription factor (TF)-gene interaction network based on key genes. B miRNA-gene interaction network based on key genes. C , E , G Overall docking models of CASP1, CXCR2, and IFIT5 proteins with estradiol, along with two-dimensional and three-dimensional spatial interaction diagrams of the ligand-protein complexes. D , F , H Overall docking models of CASP1, CXCR2, and IFIT5 proteins with methyl methanesulfonate, along with two-dimensional and three-dimensional spatial interaction diagrams of the ligand-protein complexes

Journal: BMC Medical Genomics

Article Title: Shared molecular signatures between atrial fibrillation and chronic obstructive pulmonary disease: an integrated bioinformatic analysis with experimental validation

doi: 10.1186/s12920-026-02335-4

Figure Lengend Snippet: A Transcription factor (TF)-gene interaction network based on key genes. B miRNA-gene interaction network based on key genes. C , E , G Overall docking models of CASP1, CXCR2, and IFIT5 proteins with estradiol, along with two-dimensional and three-dimensional spatial interaction diagrams of the ligand-protein complexes. D , F , H Overall docking models of CASP1, CXCR2, and IFIT5 proteins with methyl methanesulfonate, along with two-dimensional and three-dimensional spatial interaction diagrams of the ligand-protein complexes

Article Snippet: Proteins were then transferred onto the membranes using a constant current of 400 mA for 0.5 h. Following transfer, the membranes were incubated overnight at 4 °C with primary antibodies specific for CASP1 (WL03450, Wanleibio), CXCR2 (bs-1629R, Bioss), IFIT5 (CAP4911, Cohesionbio), and GAPDH (10494-1-AP, Proteintech), ensuring specific detection of target proteins.

Techniques: