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CapitalBio Corporation tm dna microarray method

CapitalBio™ <t>DNA</t> <t>microarray</t> detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified

Tm Dna Microarray Method, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/capitalbio+dna+microarray/dna+microarray+method/pmc05964880-93-3-3
Average 90 stars, based on 1 article reviews

tm dna microarray method - by Bioz Stars, 2026-10

90/100 stars

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1) Product Images from "GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun"

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun

Journal: BMC Infectious Diseases

doi: 10.1186/s12879-018-3131-8

CapitalBio™ DNA microarray detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified

Figure Legend Snippet: CapitalBio™ DNA microarray detection site layout. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Every five repeated hybrid grid points correspond to one cell of specific content. QC: surface chemical quality control probe; EC: external control probe for hybridization-based quantitation; BC: blank control; NC: negative control probe; IC: internal control probe for PCR; WT: wild-type. a : Six sites detected in the rpoB gene, Ser531Leu (TCG → TTG), Ser531Trp (TCG → TGG), His526Asp (CAC → GAC), His526Tyr (CAC → TAC), His526Leu (CAC → CTC), His526Arg (CAC → CGC), Leu511Pro (CTG → CCG), Gln513Leu (CAA → CCA), Gln513Lys (CAA → AAA), Asp516Val (GAC → GTC), Asp516Tyr (GAC → TAC), Asp516Gly (GAC → GGC) and Leu533Pro (CTG → CCG), for a total of 13 types of mutants. b : The katG gene and a locus of the inhA gene promoter were tested as isoniazid resistance-related genes. The contents of the table on the right side correspond to the microarray hybridization dot matrix on the left side in each figure. Two katG gene mutants, Ser315Thr (AGC → ACC) and Ser315Asn (AGC → AAC), and one inhA gene promoter mutant, − 15 (C → T) mutant, were identified

Techniques Used: Microarray, Hybridization, Control, Quantitation Assay, Negative Control, Mutagenesis

Common results of the CapitalBio™ DNA microarray detection spectra are shown for samples with mutation(s) at a : WT: wild-type. b : NTB: nontuberculous mycobacteria. c : rpoB gene codon 531 (TCG → TTG). d : rpoB gene codon 526 (CAC → TAC). e : katG gene codon 315 (AGC → ACC). f : inhA gene promoter − 15 (C → T)

Figure Legend Snippet: Common results of the CapitalBio™ DNA microarray detection spectra are shown for samples with mutation(s) at a : WT: wild-type. b : NTB: nontuberculous mycobacteria. c : rpoB gene codon 531 (TCG → TTG). d : rpoB gene codon 526 (CAC → TAC). e : katG gene codon 315 (AGC → ACC). f : inhA gene promoter − 15 (C → T)

Techniques Used: Microarray, Mutagenesis

Performance evaluation of the CapitalBio™ DNA microarray for rifampin and isoniazid resistance in tuberculosis cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Figure Legend Snippet: Performance evaluation of the CapitalBio™ DNA microarray for rifampin and isoniazid resistance in tuberculosis cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Techniques Used: Microarray

Performance evaluation of the CapitalBio™ DNA microarray for MDR-TB cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Figure Legend Snippet: Performance evaluation of the CapitalBio™ DNA microarray for MDR-TB cases compared with the standard drug sensitivity testing (DST) method for the 671 samples

Techniques Used: Microarray

Microarray chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples

Figure Legend Snippet: Microarray chip detection of mutations in Mycobacterium tuberculosis rpoB-RRDR relevant mutation sites for the 57 samples

Techniques Used: Microarray, Mutagenesis

Figure Legend Snippet: Microarray chip detection of rpoB-RRDR,KatG315 and inhA-15 mutation points for the 121 samples

Techniques Used: Microarray, Mutagenesis

Microarray:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The CapitalBio DNA microarray method can quickly detect Mtb drug resistance within 6 h in full.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: GeneChip analysis of resistant Mycobacterium tuberculosis with previously treated tuberculosis in Changchun
Article Snippet: We used the CapitalBio TM DNA microarray method and the DST approach as the reference standard to assess these cases in Changchun for rpoB and inhA mutations.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .

Negative Control:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .

Diagnostic Assay:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .

Mutagenesis:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .

Control:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .

Comparison:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .

Hybridization:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .

Quantitation Assay:

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Nevertheless, the CapitalBio DNA microarray method is still a very suitable method for detecting the drug resistance of Mtb .

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: Our research suggests that this algorithm may also be used for the CapitalBio DNA microarray method, but further research is needed to confirm this hypothesis.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: In a sample of 4148 cases, the CapitalBio DNA microarray method showed that 320 were resistant and 3828 were sensitive to RIF, and 342 were resistant and 3716 were sensitive to INH, of which 181 were MDR-TB.

Article Title: Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study
Article Snippet: The sensitivity and specificity obtained in this study are similar to the results obtained in a previous systematic review of the CapitalBio DNA microarray method .