Review



recombinant mouse gdf9  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 94

    Structured Review

    R&D Systems recombinant mouse gdf9
    (A) Log-likelihood ratio of obtaining iPSC vs non-iPSC fate on each day (x-axis) in 2i. Obox6+ cells in red. (B) Bright field and fluorescence images of iPSC colonies generated in 2i by overexpression of OKSM with either Zfp42 or Obox6 (or negative control). (C) Percentage of Oct4-EGFP+ colonies in 2i on day 16, for one of five experiments (Figure S6D). Error bars show standard deviation of three biological replicates. (D-F) Effect of varying concentration of <t>GDF9</t> (red) vs control (grey) on (D) Oct4-EGFP+ colonies (error bars show standard deviation); (E) the strength of iPSC signature score in bulk RNA-Seq; and (F) cellular composition assayed by scRNA-seq. (G) Schematic of the reprogramming landscape in serum. Color indicates cell-set membership. Color of TFs indicates which cell set they regulate. Color of cytokine indicates the cell class to which they signal. See also Figure S6.
    Recombinant Mouse Gdf9, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/Reconstitution+Buffer+4+(BSA%2FHCl)/pmc06402800-1304-27-30
    Average 94 stars, based on 11 article reviews
    recombinant mouse gdf9 - by Bioz Stars, 2026-11
    94/100 stars

    Images

    1) Product Images from "Optimal-transport analysis of single-cell gene expression identifies developmental trajectories in reprogramming"

    Article Title: Optimal-transport analysis of single-cell gene expression identifies developmental trajectories in reprogramming

    Journal: Cell

    doi: 10.1016/j.cell.2019.01.006

    (A) Log-likelihood ratio of obtaining iPSC vs non-iPSC fate on each day (x-axis) in 2i. Obox6+ cells in red. (B) Bright field and fluorescence images of iPSC colonies generated in 2i by overexpression of OKSM with either Zfp42 or Obox6 (or negative control). (C) Percentage of Oct4-EGFP+ colonies in 2i on day 16, for one of five experiments (Figure S6D). Error bars show standard deviation of three biological replicates. (D-F) Effect of varying concentration of GDF9 (red) vs control (grey) on (D) Oct4-EGFP+ colonies (error bars show standard deviation); (E) the strength of iPSC signature score in bulk RNA-Seq; and (F) cellular composition assayed by scRNA-seq. (G) Schematic of the reprogramming landscape in serum. Color indicates cell-set membership. Color of TFs indicates which cell set they regulate. Color of cytokine indicates the cell class to which they signal. See also Figure S6.
    Figure Legend Snippet: (A) Log-likelihood ratio of obtaining iPSC vs non-iPSC fate on each day (x-axis) in 2i. Obox6+ cells in red. (B) Bright field and fluorescence images of iPSC colonies generated in 2i by overexpression of OKSM with either Zfp42 or Obox6 (or negative control). (C) Percentage of Oct4-EGFP+ colonies in 2i on day 16, for one of five experiments (Figure S6D). Error bars show standard deviation of three biological replicates. (D-F) Effect of varying concentration of GDF9 (red) vs control (grey) on (D) Oct4-EGFP+ colonies (error bars show standard deviation); (E) the strength of iPSC signature score in bulk RNA-Seq; and (F) cellular composition assayed by scRNA-seq. (G) Schematic of the reprogramming landscape in serum. Color indicates cell-set membership. Color of TFs indicates which cell set they regulate. Color of cytokine indicates the cell class to which they signal. See also Figure S6.

    Techniques Used: Fluorescence, Generated, Over Expression, Negative Control, Standard Deviation, Concentration Assay, Control, RNA Sequencing

    Related Articles

    Recombinant:

    Article Title: Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors.
    Article Snippet: This study identified tumorigenic processes most dependent on murine HSP72 in the MMTV-PyMT mammary tumor model, which give rise to spontaneous mammary tumors that exhibit HSP72dependent metastasis to the lung.. RNA-seq expression profiling of Hspa1a/Hspa1b (Hsp72) WT and Hsp72 -/primary mammary tumors discovered significantly lower expression of genes encoding components of the extracellular matrix (ECM) in Hsp72 knockout mammary tumors compared to WT controls.. In vitro studies found that genetic or chemical inhibition of HSP72 activity in cultured collagenJo ur na l P r -p ro of expressing human or murine cells also reduces mRNA and protein levels of COL1A1 and several other ECM-encoding genes.

    Article Title: Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors
    Article Snippet: These compounds were solubilized in DMSO (Sigma, D2650), aliquoted to minimize freeze-thaw, and stored at −80 °C or −20 °C. .. Recombinant human TGF-β1 (R&D Systems, 7754-BH/CF) was solubilized in reconstitution buffer (R&D Systems, RB04) at 100 μg/mL, aliquoted, and stored at −80 °C. .. Cell culture Hs578T (ATCC, HTB-126) cells were cultured in DMEM (Gibco, 11965-092) with 10% FBS (Gibco, 10082-147) supplemented with 0.01 mg/mL human insulin (Sigma, I9278).

    Article Title: TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development
    Article Snippet: .. For TGFβ1 treatment, recombinant human TGFβ1 (7754- BH, R&D Systems) was used at 5 ng/ml for the TGFβ1 treatment group for 4 hr or 18 hr, while an equal volume of BSA (RB04, R&D Systems) was added to the control group for the same period. .. RNeasy Plus Micro Kit (Qiagen, 74034) was used to isolate RNA.

    Control:

    Article Title: TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development
    Article Snippet: .. For TGFβ1 treatment, recombinant human TGFβ1 (7754- BH, R&D Systems) was used at 5 ng/ml for the TGFβ1 treatment group for 4 hr or 18 hr, while an equal volume of BSA (RB04, R&D Systems) was added to the control group for the same period. .. RNeasy Plus Micro Kit (Qiagen, 74034) was used to isolate RNA.



    Similar Products

    97
    Thermo Fisher tris buffered saline tbs
    Tris Buffered Saline Tbs, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/TRIS-buffered+saline+(TBS%2C+)+pH+7%2E4/pmc13284439-129-11-33
    Average 97 stars, based on 1 article reviews
    tris buffered saline tbs - by Bioz Stars, 2026-11
    97/100 stars
      Buy from Supplier

    94
    Zymo Research m wash buffer
    M Wash Buffer, supplied by Zymo Research, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/M-Wash+Buffer/pm42882841-98-8-18
    Average 94 stars, based on 1 article reviews
    m wash buffer - by Bioz Stars, 2026-11
    94/100 stars
      Buy from Supplier

    95
    Zymo Research elution buffer
    Elution Buffer, supplied by Zymo Research, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/DNA+Elution+Buffer/bio_rxiv__64898__2026__10__15__759447-274-9-11
    Average 95 stars, based on 1 article reviews
    elution buffer - by Bioz Stars, 2026-11
    95/100 stars
      Buy from Supplier

    99
    Bio-Rad mixed 4
    Mixed 4, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/4x+Laemmli+Sample+Buffer/bio_rxiv__64898__2026__10__12__758510-233-2-60
    Average 99 stars, based on 1 article reviews
    mixed 4 - by Bioz Stars, 2026-11
    99/100 stars
      Buy from Supplier

    95
    Zymo Research dna digestion buffer
    Dna Digestion Buffer, supplied by Zymo Research, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/DNA+Digestion+Buffer/pm42892174-149-22-15
    Average 95 stars, based on 1 article reviews
    dna digestion buffer - by Bioz Stars, 2026-11
    95/100 stars
      Buy from Supplier

    98
    New England Biolabs neb buffer 4
    Neb Buffer 4, supplied by New England Biolabs, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/NEBuff+4/pm42854686-911-5-8
    Average 98 stars, based on 1 article reviews
    neb buffer 4 - by Bioz Stars, 2026-11
    98/100 stars
      Buy from Supplier

    95
    Zymo Research dna elution buffer
    Dna Elution Buffer, supplied by Zymo Research, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/DNA+Elution+Buffer/pm42836610-99-20-23
    Average 95 stars, based on 1 article reviews
    dna elution buffer - by Bioz Stars, 2026-11
    95/100 stars
      Buy from Supplier

    98
    Thermo Fisher 4 morpholineethanesulfonic acid
    4 Morpholineethanesulfonic Acid, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/NuPAGE+MES+SDS+Running+Buffer+(20X)/10__1016_slash_j__fufo__2026__101205-63-20-51
    Average 98 stars, based on 1 article reviews
    4 morpholineethanesulfonic acid - by Bioz Stars, 2026-11
    98/100 stars
      Buy from Supplier

    99
    Bio-Rad 4×x laemmli sample buffer
    4×X Laemmli Sample Buffer, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/buffer+4/4x+Laemmli+Sample+Buffer/10__1007_slash_s00253___026___13937___4-84-3-7
    Average 99 stars, based on 1 article reviews
    4×x laemmli sample buffer - by Bioz Stars, 2026-11
    99/100 stars
      Buy from Supplier

    Image Search Results