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Takeda brain eqtl data sets
Brain Eqtl Data Sets, supplied by Takeda, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/brain+eqtl+data+set/brain+eqtl+datasets/pmc08848643-346-3-24
Average 90 stars, based on 1 article reviews
brain eqtl data sets - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Regulatory mechanisms of major depressive disorder risk variants.
Article Snippet: Major depressive disorder (MDD) is one of the most prevalent psychiatric disorders and a leading cause of disability worldwide.. Though recent genome-wide association studies (GWAS) have identified multiple risk variants for MDD, how these variants confer MDD risk remains largely unknown.. Here we systematically characterize the regulatory mechanism of MDD risk variants using a functional genomics approach.

Article Title: Convergent lines of evidence support NOTCH4 as a schizophrenia risk gene.
Article Snippet: © Author(s) (or their employer(s)) 2020.. No commercial reuse.. See rights and permissions.

Article Title: Functional variant rs2270363 on 16p13.3 confers schizophrenia risk by regulating NMRAL1
Article Snippet: .. One of the brain eQTL datasets used in this study was generated as part of the CommonMind Consortium supported by funding from Takeda Pharmaceuticals Company Limited, F. Hoffman-La Roche Ltd and NIH grants R01MH085542, R01MH093725, P50MH066392, P50MH080405, R01MH097276, RO1-MH-075916, P50M096891, P50MH084053S1, R37MH057881 and R37MH057881S1, HHSN271201300031C, AG02219, AG05138 and MH06692. ..

Article Title: A missense variant in NDUFA6 confers schizophrenia risk by affecting YY1 binding and NAGA expression.
Article Snippet: Genome-wide association studies (GWASs) have revealed that genetic variants at the 22q13.2 risk locus were robustly associated with schizophrenia.. However, the causal variants at this risk locus and their roles in schizophrenia remain elusive.. Here we identify the risk missense variant rs1801311 (located in the 1st exon of NDUFA6 gene) as likely causal for schizophrenia at 22q13.2 by disrupting binding of YY1, TAF1, and POLR2A.

Article Title: Functional genomics elucidates regulatory mechanisms of Parkinson’s disease-associated variants
Article Snippet: Also was supported by the Key Research Project of Yunnan Province (202101AS070055), the Open Research Fund of Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province (KIZ, CAS), the Innovative Research Team of Science and Technology department of Yunnan Province (2019HC004) to X-J.L., the Western Light Innovative Research Team of Chinses Academy of Sciences, and the National Nature Science Foundation of China (31970561 to X.J.L), the CAS “Light of West China” Program and Yunnan Fundamental Research Project (202001AT070099) to JWL. .. One of the brain eQTL data sets used in this study were generated as part of the Common Mind Consortium supported by funding from Takeda Pharmaceuticals Company Limited, F. Hoffman-La Roche Ltd, and NIH grants R01MH085542, R01MH093725, P50MH066392, P50MH080405, R01MH097276, RO1-MH-075916, P50M096891, P50MH084053S1, R37MH057881 and R37MH057881S1, HHSN271201300031C, AG02219, AG05138, and MH06692. ..

Article Title: Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice.
Article Snippet: .. The eQTL data in CommonMind dataset were generated as part of the CommonMind Con‐ sortium supported by funding from Takeda Pharmaceuticals Company Lim‐ ited, F. Hoffman‐La Roche Ltd. and NIH grants R01MH085542, R01MH093725, P50MH066392, P50MH080405, R01MH097276, RO1‐MH‐075916, P50M096891, P50MH084053S1, R37MH057881, and R37MH057881S1, HHSN271201300031C, AG02219, AG05138, and MH06692. ..

Article Title: Transcriptome-Wide Association Study Provides Insights Into the Genetic Component of Gene Expression in Anxiety
Article Snippet: .. One of the brain eQTL datasets used in this study were generated as part of the CommonMind Consortium supported by funding from Takeda Pharmaceuticals Company Limited, F. Hoffman-La Roche Ltd. and NIH grants R01MH085542, R01MH093725, P50MH066392, P50MH080405, R01MH097276, RO1-MH-075916, P50M096891, P50MH084053S1, R37MH057881 and R37MH057881S1, HHSN271201300031C, AG02219, AG05138 and MH06692. ..



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