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three-dimensional (3d) bone morphometric software  (Siemens AG)

 
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    Structured Review

    Siemens AG three-dimensional (3d) bone morphometric software
    Effects of LLLT on MRONJ-like mouse model. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment group; Zol: treated with Zol group; Zol + LLLT: treated with Zol and LLLT group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed <t>3D</t> images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification <t>of</t> <t>BMD</t> and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Green dot lines represent necrotic bones. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G H&E staining shows the human gingiva of healthy and MRONJ patients. Black dotted boxes represent magnified boxed regions. Black arrows represent inflammatory cells. Scale bar = 200 μm (upper), scale bar = 50 μm (lower). H Masson’s trichrome staining shows tooth extraction sockets-wound healing in each group. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). I Masson’s trichrome staining shows collagen arrangement in human gingiva tissues. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
    Three Dimensional (3d) Bone Morphometric Software, supplied by Siemens AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/bone+morphometric+software/three+dimensional++3d++bone+morphometric+software/pmc09832759-73-20-24
    Average 90 stars, based on 1 article reviews
    three-dimensional (3d) bone morphometric software - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Low-level laser therapy prevents medication-related osteonecrosis of the jaw-like lesions via IL-1RA-mediated primary gingival wound healing"

    Article Title: Low-level laser therapy prevents medication-related osteonecrosis of the jaw-like lesions via IL-1RA-mediated primary gingival wound healing

    Journal: BMC Oral Health

    doi: 10.1186/s12903-022-02678-1

    Effects of LLLT on MRONJ-like mouse model. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment group; Zol: treated with Zol group; Zol + LLLT: treated with Zol and LLLT group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Green dot lines represent necrotic bones. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G H&E staining shows the human gingiva of healthy and MRONJ patients. Black dotted boxes represent magnified boxed regions. Black arrows represent inflammatory cells. Scale bar = 200 μm (upper), scale bar = 50 μm (lower). H Masson’s trichrome staining shows tooth extraction sockets-wound healing in each group. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). I Masson’s trichrome staining shows collagen arrangement in human gingiva tissues. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
    Figure Legend Snippet: Effects of LLLT on MRONJ-like mouse model. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment group; Zol: treated with Zol group; Zol + LLLT: treated with Zol and LLLT group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Green dot lines represent necrotic bones. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G H&E staining shows the human gingiva of healthy and MRONJ patients. Black dotted boxes represent magnified boxed regions. Black arrows represent inflammatory cells. Scale bar = 200 μm (upper), scale bar = 50 μm (lower). H Masson’s trichrome staining shows tooth extraction sockets-wound healing in each group. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). I Masson’s trichrome staining shows collagen arrangement in human gingiva tissues. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Techniques Used: Staining

    Application of IL-1RA NAb impairs the capacity of LLLT to promote gingival wound healing. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment, but treated with negative control antibodies group; Zol: treated with Zol and negative control antibodies group; Zol + LLLT: treated with Zol, LLLT, and negative control antibodies group; Zol + LLLT + IL-1RA: treated with Zol, LLLT, and IL-1RA NAb group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G , H Images of IL-1β and TNF-α IHC staining of the mouse gingival wound. Scale bar = 100 μm. (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
    Figure Legend Snippet: Application of IL-1RA NAb impairs the capacity of LLLT to promote gingival wound healing. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment, but treated with negative control antibodies group; Zol: treated with Zol and negative control antibodies group; Zol + LLLT: treated with Zol, LLLT, and negative control antibodies group; Zol + LLLT + IL-1RA: treated with Zol, LLLT, and IL-1RA NAb group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G , H Images of IL-1β and TNF-α IHC staining of the mouse gingival wound. Scale bar = 100 μm. (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Techniques Used: Negative Control, Staining, Immunohistochemistry



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    Effects of LLLT on MRONJ-like mouse model. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment group; Zol: treated with Zol group; Zol + LLLT: treated with Zol and LLLT group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed <t>3D</t> images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification <t>of</t> <t>BMD</t> and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Green dot lines represent necrotic bones. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G H&E staining shows the human gingiva of healthy and MRONJ patients. Black dotted boxes represent magnified boxed regions. Black arrows represent inflammatory cells. Scale bar = 200 μm (upper), scale bar = 50 μm (lower). H Masson’s trichrome staining shows tooth extraction sockets-wound healing in each group. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). I Masson’s trichrome staining shows collagen arrangement in human gingiva tissues. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
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    Image Search Results


    Effects of LLLT on MRONJ-like mouse model. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment group; Zol: treated with Zol group; Zol + LLLT: treated with Zol and LLLT group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Green dot lines represent necrotic bones. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G H&E staining shows the human gingiva of healthy and MRONJ patients. Black dotted boxes represent magnified boxed regions. Black arrows represent inflammatory cells. Scale bar = 200 μm (upper), scale bar = 50 μm (lower). H Masson’s trichrome staining shows tooth extraction sockets-wound healing in each group. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). I Masson’s trichrome staining shows collagen arrangement in human gingiva tissues. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Journal: BMC Oral Health

    Article Title: Low-level laser therapy prevents medication-related osteonecrosis of the jaw-like lesions via IL-1RA-mediated primary gingival wound healing

    doi: 10.1186/s12903-022-02678-1

    Figure Lengend Snippet: Effects of LLLT on MRONJ-like mouse model. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment group; Zol: treated with Zol group; Zol + LLLT: treated with Zol and LLLT group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Green dot lines represent necrotic bones. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G H&E staining shows the human gingiva of healthy and MRONJ patients. Black dotted boxes represent magnified boxed regions. Black arrows represent inflammatory cells. Scale bar = 200 μm (upper), scale bar = 50 μm (lower). H Masson’s trichrome staining shows tooth extraction sockets-wound healing in each group. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). I Masson’s trichrome staining shows collagen arrangement in human gingiva tissues. Yellow dotted boxes represent magnified boxed regions. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Article Snippet: The area of interest was chosen, and bone mineral density (BMD) and bone volume/total volume (BV/TV) were quantified by three-dimensional (3D) bone morphometric software (SIEMENS, Munich, Germany).

    Techniques: Staining

    Application of IL-1RA NAb impairs the capacity of LLLT to promote gingival wound healing. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment, but treated with negative control antibodies group; Zol: treated with Zol and negative control antibodies group; Zol + LLLT: treated with Zol, LLLT, and negative control antibodies group; Zol + LLLT + IL-1RA: treated with Zol, LLLT, and IL-1RA NAb group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G , H Images of IL-1β and TNF-α IHC staining of the mouse gingival wound. Scale bar = 100 μm. (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Journal: BMC Oral Health

    Article Title: Low-level laser therapy prevents medication-related osteonecrosis of the jaw-like lesions via IL-1RA-mediated primary gingival wound healing

    doi: 10.1186/s12903-022-02678-1

    Figure Lengend Snippet: Application of IL-1RA NAb impairs the capacity of LLLT to promote gingival wound healing. A The study's experimental protocols are depicted in this diagram. B Representative intraoral photos. (Ctrl: non-drug treatment, but treated with negative control antibodies group; Zol: treated with Zol and negative control antibodies group; Zol + LLLT: treated with Zol, LLLT, and negative control antibodies group; Zol + LLLT + IL-1RA: treated with Zol, LLLT, and IL-1RA NAb group). Green dotted lines represent unhealed gingiva. C MicroCT reconstructed 3D images of tooth sockets. Green dotted lines represent tooth sockets. D , E Quantification of BMD and BV/TV in each group. F H&E staining shows tooth extraction sockets-wound healing in each group. Black dotted boxes represent magnified boxed regions. Green dotted lines represent unhealed gingiva. Scale bar = 200 μm (upper), scale bar = 100 μm (lower). G , H Images of IL-1β and TNF-α IHC staining of the mouse gingival wound. Scale bar = 100 μm. (* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)

    Article Snippet: The area of interest was chosen, and bone mineral density (BMD) and bone volume/total volume (BV/TV) were quantified by three-dimensional (3D) bone morphometric software (SIEMENS, Munich, Germany).

    Techniques: Negative Control, Staining, Immunohistochemistry