bioactive small molecule library (Selleck Chemicals)

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Selleck Chemicals bioactive small molecule library
Bioactive Small Molecule Library, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 95/100, based on 108 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bioactive+small+molecules/Bioactive+Compound+Library-I/pm40108413-271-1-6
Average 95 stars, based on 108 article reviews

bioactive small molecule library - by Bioz Stars, 2026-11

95/100 stars

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Docking Assay:

Article Title: Chromobox 2 inhibition: A novel activity of alisertib, an Aurora A kinase inhibitor
Article Snippet: .. A computational-based molecular docking screen was performed using the SelleckChem Bioactive library to identify inhibitors of CBX2. ..

Article Title: Chromobox 2 inhibition: A novel activity of alisertib, an Aurora A kinase inhibitor
Article Snippet: .. A) Molecular docking of the SelleckChem Bioactive Library into CBX2 using CBXi as a reference ligand in the CBX2-CBXi complex determined from Yasara molecular dynamic simulations. ..

In Silico:

Article Title: Duloxetine ameliorates cerebral ischemic injury by inhibiting autophagy.
Article Snippet: To cite this article: Alice Viotti , Claudia Molinaro , Jessica Perego , Andrea Fossaghi , Chiara Parravicini , Eliana Laurenzano , Antonella Borreca , Marco Piccoli , Luigi Anastasia , Susanna Manenti , Annamaria Finardi , Alessandra Mandelli , Michela Matteoli , Ivano Eberini , Paola Panina , Gianvito Martino & Luca Muzio (05 Mar 2026): Duloxetine ameliorates cerebral ischemic injury by inhibiting autophagy, Autophagy, DOI: 10.1080/15548627.2026.2641616

Functional Assay:

Activity Assay:

Article Title: β3GnT2-mediated N-glycosylation of EGFR and LDLR drives glioblastoma progression and can be targeted by AST-1306
Article Snippet: .. Screen small-molecule compounds that inhibit β3GnT2 activity Download the structure of the β3GnT2 protein (PDB ID:8sz3) and the structures of 9,970 compounds (Bioactive Compound Library-I (L1700), Selleck.cn). ..

Fluorescence:

In Vitro:

In Vivo:

Biomarker Discovery:

Drug discovery:

Article Title: Onvansertib and vilazodone inhibit SARS-CoV-2 replication via suppression of METTL3 RNA-m 6 A enzymatic activity.
Article Snippet: This is a PDF of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability.. This version will undergo additional copyediting, typesetting and review before it is published in its final form.. As such, this version is no longer the Accepted Manuscript, but it is not yet the definitive Version of Record; we are providing this early version to give early visibility of the article.

Article Title: ‘Smart’ hydrogel for the radiosensitization and sustained delivery of therapeutics triggered by irradiation
Article Snippet: .. Compound from the Selleckchem Bioactive Compound Library I was added to each well at 100 nM (approximately 3200 compounds). ..

Article Title: RNaseH2 inhibition potentiates temozolomide response in patient derived glioblastoma cells.
Article Snippet: .. Within Compound library Number of compounds Asinex PPI (Non-Macrocyclic) 966 BioMol Kinase Inhibitor Library 70 BioMol Known bioactives 79 ChemBridge Diversity 17255 ChemDiv ChemBioNet 16,308 Enamine Diversity 27698 Enzo Chemical Genomics 207 Enzo Pathway Targeting 205 Enzo Receptor De-Orphaning 70 MedChemExpress Epigenetics 2186 Prestwick Chemical Library (Approved Drugs) 1516 Prestwick Original Molecules (NOCE) 344 Selleck Bioactive Compound Library-I 989 Selleck Cambridge Cancer 352 Selleck Kinase 170 Selleck OncoSet 443 Selleck Tyrosine Kinase 171 Sigma LOPAC 1255 Tocris Mini 1110 Table 3. ..

Review