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bioactive compound libraries (TargetMol)

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TargetMol bioactive compound libraries
Bioactive Compound Libraries, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bioactive+compound+library/Bioactive+Lipid+Compound+Library/pm41963079-166-11-14
Average 94 stars, based on 5 article reviews

bioactive compound libraries - by Bioz Stars, 2026-10

94/100 stars

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Drug discovery:

Article Title: Dual targeting of NCF1 and NLRP3 by roburic acid orchestrates redox homeostasis and inhibits macrophage death in septic lung injury
Article Snippet: .. The bioactive lipid compound library used for the primary screen was purchased from TargetMol Bio. .. The bioactive lipid compound library used for the primary screen was purchased from TargetMol Bio.

Article Title: CD55-expressing myeloid-derived suppressor cells (MDSCs) drive cancer immunoevasion
Article Snippet: For small-molecule inhibitors capable of disrupting the CD55-PYGL interaction, structure-based virtual screening was conducted using AutoDock Vina (V.1.2.3, The Scripps Research Institute). .. A diverse compound library of approximately 25,031 molecules was compiled from bioactive compound libraries (TargetMol), Food and Drug Administration (FDA)-approved drug libraries, and natural product collections. ..

Article Title: Dual targeting of NCF1 and NLRP3 by roburic acid orchestrates redox homeostasis and inhibits macrophage death in septic lung injury.
Article Snippet: For the initial screening and standard inflammasome activation assays, BMDMs or differentiated THP-1 cells were primed with LPS (1 μg/ mL, HY-B2176) for 2 h. Following priming, the cell culture supernatant was discarded to remove excess LPS. .. The bioactive lipid compound library used for the primary screen was purchased from TargetMol Bio. ..

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other:

Article Title: CD55-expressing myeloid-derived suppressor cells (MDSCs) drive cancer immunoevasion.
Article Snippet: RNA integrity was assessed using a Bioanalyzer 2100 (Agilent), and samples with an RNA integrity number (RIN) >7.0 were selected for library preparation.

Activity Assay:

Article Title: Recent advances in application of computer-aided drug design in anti-COVID-19 Virials Drug Discovery.
Article Snippet: .. Through structure-based virtual screening, Quanjie Li et al. identified corilagin (RAI-S-37) as a non-nucleoside inhibitor of SARS-CoV-2 RdRp from 15,220 compounds in the DrugBank and TargetMol bioactive compound libraries, which can directly bind to RdRp and effectively inhibit the polymerase activity. ..