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ComboSyn Inc compusyn software
Results of CI, Fa, and DRI in drug reaction at the various concentrations of Apatinib and Piperine in combined treatments which were measured by <t> Compusyn software. </t> Data showed as mean ± standard deviation.

Results of CI, Fa, and DRI in drug reaction at the various concentrations of Apatinib and Piperine in combined treatments which were measured by <t> Compusyn software. </t> Data showed as mean ± standard deviation.

Compusyn Software, supplied by ComboSyn Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/based+interactive+tool+cyt/compusyn+software/pmc09106969-43-11-13
Average 90 stars, based on 1 article reviews

compusyn software - by Bioz Stars, 2026-10

90/100 stars

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1) Product Images from "Regulatory Effects of Apatinib in Combination with Piperine on MDM-2 Gene Expression, Glutathione Peroxidase Activity and Nitric Oxide level as Mechanisms of Cytotoxicity in Colorectal Cancer Cells"

Article Title: Regulatory Effects of Apatinib in Combination with Piperine on MDM-2 Gene Expression, Glutathione Peroxidase Activity and Nitric Oxide level as Mechanisms of Cytotoxicity in Colorectal Cancer Cells

Journal: Advanced Pharmaceutical Bulletin

doi: 10.34172/apb.2022.040

Results of CI, Fa, and DRI in drug reaction at the various concentrations of Apatinib and Piperine in combined treatments which were measured by Compusyn software. Data showed as mean ± standard deviation.

Figure Legend Snippet: Results of CI, Fa, and DRI in drug reaction at the various concentrations of Apatinib and Piperine in combined treatments which were measured by Compusyn software. Data showed as mean ± standard deviation.

Techniques Used: Software

Concentration Assay:

Article Title: Unveiling Synergistic Antioxidant Effects of Green Tea and Peppermint: Role of Polyphenol Interactions and Blend Preparation.
Article Snippet: .. Both the CI and DRI, along with the concentration required for 50% inhibition (IC50), were calculated using median-effect analysis via CompuSyn software version 1.0.1. (ComboSyn, Inc., Paramus, NJ, USA). ..

Inhibition:

Software:

Article Title: Martinostat as a novel HDAC inhibitor to overcome tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Article Snippet: The samples were analyzed using a FACSCalibur flow cytometer (BD Biosciences), and the data were processed using the FlowJo software (version 10.4.1; Treestar, Ashland, OR, USA). .. The combination index (CI) was calculated using CompuSyn software (ComboSyn Inc., Paramus, NJ, USA). .. The intracellular ATP content was determined using a CellTiter-Glo ® Luminescent Cell Viability Assay (Promega, Madison, WI, USA).

Article Title: EZH2 inhibitor SHR2554 enhances the anti-tumor efficacy of HDAC inhibitor Chidamide through STAT1 in T-cell lymphoma.
Article Snippet: ✉email: lxywumeng@foxmail.com; dingdingply1981@163.com; zhu-jun2017@outlook.com Edited by Dr Gemma Kelly www.nature.com/cddis Official journal of CDDpress 1 2 3 4 5 6 7 8 9 0;,: Cell viability was assessed using the CellTiter-Glo Luminescent Cell Viability Assay System (Promega, Madison, USA, #G7572). .. Synergistic effects were analyzed using CompuSyn software (ComboSyn Inc, NJ, USA) [20]. .. Cell apoptosis and cell cycle assays For the apoptosis assay, cells were resuspended in 1× Binding Buffer and stained with Annexin V-FITC and propidium iodide (PI) using an apoptosis detection kit (Dojindo Laboratories, Kumamoto, Japan, #AD10).

Article Title: A brain-penetrant CDK4/6 inhibitor - AU3-14 shows robust anti-tumor efficacy against glioblastoma.
Article Snippet: For combination studies, cells were treated with AU3–14, TMZ at 400 μM, or their combination for 144 h. Pre-treatment schedules involved sequential exposure to each compound for 72 h. Media and compounds were replaced every 72 h. After treatment, 50 μL of MTT solution (3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide; ThermoFisher Scientific, Victoria, Australia) was added and the absorbance was measured at 560 nm using a PerkinElmer plate reader (Buckinghamshire, UK). .. The effects of the combination treatments were analyzed using the Chou-Talalay method [36] through the CompuSyn software (ComboSyn, New Jersey, USA), where combination index (CI) values of < 1, 1, and > 1 were indicative of synergistic, additive, and antagonistic interactions, respectively. .. Half-maximal growth inhibitory concentrations (GI50) were determined using GraphPad Prism 10 (California, USA) employing a nonlinear regression model with a four-parameter logistic fit.

Article Title: EZH2 inhibitor SHR2554 enhances the anti-tumor efficacy of HDAC inhibitor Chidamide through STAT1 in T-cell lymphoma
Article Snippet: Cell viability was assessed using the CellTiter-Glo Luminescent Cell Viability Assay System (Promega, Madison, USA, #G7572). .. Synergistic effects were analyzed using CompuSyn software (ComboSyn Inc, NJ, USA) [ ]. .. For the apoptosis assay, cells were resuspended in 1× Binding Buffer and stained with Annexin V-FITC and propidium iodide (PI) using an apoptosis detection kit (Dojindo Laboratories, Kumamoto, Japan, #AD10).

other:

Article Title: Hinokiflavone is a novel CK2 inhibitor promoting apoptosis and synergizing with chemotherapeutic agents in cisplatin resistant bladder cancer cells.
Article Snippet: The combination index (CI) values were determined using CompuSyn 1.0.1 software (ComboSyn, Inc., Paramus, NJ, USA; www.combosyn.com), where a CI value below one indicates synergism.

Article Title: Hinokiflavone is a novel CK2 inhibitor promoting apoptosis and synergizing with chemotherapeutic agents in cisplatin resistant bladder cancer cells
Article Snippet: The combination index (CI) values were determined using CompuSyn 1.0.1 software (ComboSyn, Inc., Paramus, NJ, USA; www.combosyn.com ), where a CI value below one indicates synergism.

Article Title: Metabolic Collapse in Pancreatic Cancer via Combined Inhibition of Lactate Export and Thioredoxin Reductase
Article Snippet: Combination index (CI) values were calculated using CompuSyn 1.0 software (ComboSyn Inc., Paramus, NJ, USA).

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