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Bruker Corporation autoflex massarray analyzer 4 maldi-tof ms
Autoflex Massarray Analyzer 4 Maldi Tof Ms, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/autoflex+massarray/autoflex+massarray+mass+spectrometer/pmc06239293-133-21-20
Average 90 stars, based on 1 article reviews
autoflex massarray analyzer 4 maldi-tof ms - by Bioz Stars, 2026-10
90/100 stars

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Mass Spectrometry:

Article Title: Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.
Article Snippet: The functional interaction of BAFF and APRIL with TNF receptor superfamily members BAFFR, TACI and BCMA is crucial for development and maintenance of humoral immunity in mice and humans.. Using a candidate gene approach, we identified homozygous and heterozygous mutations in TNFRSF13B, encoding TACI, in 13 individuals with common variable immunodeficiency.. Homozygosity with respect to mutations causing the amino acid substitutions S144X and C104R abrogated APRIL binding and resulted in loss of TACI function, as evidenced by impaired proliferative response to IgM-APRIL costimulation and defective class switch recombination induced by IL-10 and APRIL or BAFF.

Article Title: Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach.
Article Snippet: Based on titration experiments using the PicoGreen assay (Molecular Probes, Eugene, Oregon, USA), samples of 5 ng of DNA isolated from normal and tumor tissue of the patients were then subjected to MassEXTEND assay (Sequenom Inc., San Diego, CA, USA) as described in Supplementary methods at Oncogene’s website. .. The SpectroCHIPS were analysed by an Autoflex MassARRAY mass spectrometer (Bruker Daltonics, Billerica, MA, USA). ..

other:

Article Title: Rapid Sputum Multiplex Detection of the M. tuberculosis Complex (MTBC) and Resistance Mutations for Eight Antibiotics by Nucleotide MALDI-TOF MS
Article Snippet: After desalting with SpectroClean Resin, the samples were loaded onto the matrix of the SpectroCHIP ® using a MassARRAY ® Nanodispenser RS1000 and then analysed using a Bruker Autoflex MassARRAY ® Analyzer 4 MALDI-TOF MS. Data were collected and analysed using Type4 software (SEQUENOM).

Article Title: Mutational monitoring of EGFR T790M in cfDNA for clinical outcome prediction in EGFR -mutant lung adenocarcinoma
Article Snippet: After desalting with SpectroClean Resin, samples were loaded onto the matrix of SpectroCHIP by MassARRAY Nanodispenser RS1000 then analyzed by Bruker Autoflex MassARRAY Analyzer 4 MALDI-TOF MS. Data were collected and analyzed by MassARRAY Typer (version 4) software (SEQUENOM).

Article Title: Large-scale zygosity testing using single nucleotide polymorphisms.
Article Snippet: Twin Research and Human Genetics Volume 10 Number 4 pp.. 604–625 A for performing robust genetic and statistical analyses on twins is correctly assigned zygosities.. In order to increase the power to detect small risk factors of disease, zygosity testing should also be amenable for high throughput screening.

Article Title: Novel mutations in TACI (TNFRSF13B) causing common variable immunodeficiency.
Article Snippet: Introduction Common variable immunodeficiency (CVID) is a heterogeneous syndrome characterized by impaired immunoglobulin production.. The disorder is also characterized by co-occurrence of autoimmune, lymphoproliferative, and granulomatous diseases.. Mutations in the gene encoding TACI (Transmembrane Activator and CAML Interactor, TNFRSF13B) were previously found to be associated with CVID.



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Genome-wide significant association with keratoconus (data shown in chronological order)

Journal: Molecular Genetics and Genomics

Article Title: Genomic strategies to understand causes of keratoconus

doi: 10.1007/s00438-016-1283-z

Figure Lengend Snippet: Genome-wide significant association with keratoconus (data shown in chronological order)

Article Snippet: RAB3GAP1 , Australian Caucasian , 524/2761 , rs4954218 , 9.26 × 10 −9 , – , Sequenom Autoflex MassArray Illumina HumanHap610-Quad BeadChip , Bae et al. ( ) .

Techniques: Genome Wide, Northern Blot

Genome-wide significant association with keratoconus (data shown in chronological order)

Journal: Molecular Genetics and Genomics

Article Title: Genomic strategies to understand causes of keratoconus

doi: 10.1007/s00438-016-1283-z

Figure Lengend Snippet: Genome-wide significant association with keratoconus (data shown in chronological order)

Article Snippet: RXRA - COL5A1 , Australian/Caucasian (US) , 874/6085 , rs1536482 , 2.6 × 10 −7 , - , Sequenom Autoflex MassArray Illumina HumanHap610-Quad BeadChip Illumina HumanCNV370-Quad BeadChip , Lu et al. ( ) .

Techniques: Genome Wide, Northern Blot