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microarray-based methylation assessment of single sample  (INFINIUM Inc)

 
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    INFINIUM Inc microarray-based methylation assessment of single sample
    Summary of candidate gene and genome-wide techniques for DNA methylation analysis a
    Microarray Based Methylation Assessment Of Single Sample, supplied by INFINIUM Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/array-based+methylation+analysis/microarray/pmc02926750-11-36-88
    Average 90 stars, based on 1 article reviews
    microarray-based methylation assessment of single sample - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Chromatin Remodeling in Mammary Gland Differentiation and Breast Tumorigenesis"

    Article Title: Chromatin Remodeling in Mammary Gland Differentiation and Breast Tumorigenesis

    Journal: Cold Spring Harbor Perspectives in Biology

    doi: 10.1101/cshperspect.a004515

    Summary of candidate gene and genome-wide techniques for DNA methylation analysis a
    Figure Legend Snippet: Summary of candidate gene and genome-wide techniques for DNA methylation analysis a

    Techniques Used: Genome Wide, DNA Methylation Assay, Cloning, Methylation Sequencing, Methylation, Combined Bisulfite Restriction Analysis Assay, Microarray, Hybridization, Ligation, Amplification, DNA Amplification, Methylated DNA Immunoprecipitation, Immunoprecipitation, Next-Generation Sequencing, Methylated DNA Immunoprecipitation Sequencing

    Related Articles

    other:

    Article Title: Developmental programming of the HPA axis and related behaviours: epigenetic mechanisms
    Article Snippet: An additional challenge is that these techniques are based on microarray technologies, such that the number of sites amenable to distinguish cell types is limited to a fraction of CpG sites that can be potentially methylated (e.g. <2% in the case of Infinium microarrays).

    Article Title: Comprehensive Bioinformatics Analyses and Experimental Validation of the Cell Cycle Related Protein SAPCD2 as a New Biomarker and Potential Therapeutic Target in Pancreatic Cancer
    Article Snippet: Each probe (Infinium Human Methylation 450 microarray data) was indicated on the left side, and the numbers on the right side indicated the correlation coefficient or P value.

    Microarray:

    Article Title: Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma
    Article Snippet: .. In the past decade, the advent of genome-scale analysis techniques, such as Infinium microarray systems, has revolutionized the field and has opened up the new era of epigenomics. ..

    Article Title: SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia.
    Article Snippet: .. We sought to investigate this SNP in our pediatric AML cohorts for association with clinical outcome, however the rs6102991 SNP is not included on the Infinium Omni2.5Exome-8 Kit microarray. ..

    Article Title: A Targeted Epigenetic Clock for the Prediction of Biological Age
    Article Snippet: .. Overlap with Infinium microarray data [ ] , 120 , 60 , 60. ..

    Article Title: Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer
    Article Snippet: .. We preliminarily selected tumor-specific methylated regions from the Infinium 450 K microarray data downloaded from TCGA. ..

    Article Title: The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
    Article Snippet: .. Finally, the single-allele resolution of RRBS provided initial insights into epigenetic tumor heterogeneity in glioblastoma, and it distinguishes our approach from recent studies that used the Infinium microarray platform for diagnostic classification of brain tumors 17 , 52 . ..

    Genome Wide:

    Article Title: DNA methylation QTL analysis identifies new regulators of human longevity
    Article Snippet: .. Compared to Infinium microarrays, RRBS provides higher genome-wide coverage, single-site and single-allele resolution, and insights into DNA methylation heterogeneity ( ). ..

    DNA Methylation Assay:

    Article Title: DNA methylation QTL analysis identifies new regulators of human longevity
    Article Snippet: .. Compared to Infinium microarrays, RRBS provides higher genome-wide coverage, single-site and single-allele resolution, and insights into DNA methylation heterogeneity ( ). ..

    Methylation:

    Article Title: Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer
    Article Snippet: .. We preliminarily selected tumor-specific methylated regions from the Infinium 450 K microarray data downloaded from TCGA. ..

    Diagnostic Assay:

    Article Title: The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
    Article Snippet: .. Finally, the single-allele resolution of RRBS provided initial insights into epigenetic tumor heterogeneity in glioblastoma, and it distinguishes our approach from recent studies that used the Infinium microarray platform for diagnostic classification of brain tumors 17 , 52 . ..



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    Image Search Results


    Details of the included studies concerning LBP-related epigenetic regulation: DNA methylation in peripheral blood cells. Studies are listed in chronological order.

    Journal: International Journal of Molecular Sciences

    Article Title: Epigenetic Factors Related to Low Back Pain: A Systematic Review of the Current Literature

    doi: 10.3390/ijms24031854

    Figure Lengend Snippet: Details of the included studies concerning LBP-related epigenetic regulation: DNA methylation in peripheral blood cells. Studies are listed in chronological order.

    Article Snippet: Genome-wide association study (GWAS) (II) , Discovery cohort: 32 - Control group: 16 - Low back pain group: 16 Validation cohort: 63 - Control group: 16 - Low back pain group: 37 , Discovery cohort: - Control females: 43.8 ± 4.6 - Low back pain females: 41.3 ± 3.8 - Control males: 43.8 ± 4.0 - Low back pain males: 42.6 ± 3.6 Males: 16 (50%) Females: 16 (50%) Validation cohort: - Control females: 38.5 ± 3.5 - Low back pain females: 46.1 ± 2.7 - Control males: 43.1 ± 3.2 - Low back pain males: 48.4 ± 2.6 Males: 31 (49%) Females: 32 (51%) Caucasian , Canadian adaptation of NIH low back pain taskforce, DN4 and ODI \ NS , T cells isolated from peripheral blood Array-based methylation analyis (Illumina) after bisulfite treatment, followed by validation by pyrosequencing , 850,000 CpG sites , Of the 736,414 CpGs identified in men, 179 were hypermethylated and 240 were hypomethylated in LBP patients compared to controls. Of the 735,863 CpGs identified in women, 601 were hypermethylated and 1895 were hypomethylated ( p -value < 0.05). The generation of a polygenic methylation score for LBP in men and women with three surrogate CpG loci: cg07420274 for women; cg21149944 and cg22831726 for men. In women, the percentage of methylation at position cg07420274 was 39.5 ± 6 2.7% and 49.7 ± 6 3.2% in the control ( n = 21) and LBP groups ( n = 25), respectively ( p < 0.05). A statistically significant association between methylation at cg07420274 and LBP was observed (OR = 1.05, 95% CI: 1.01–1.11, p < 0.03). In men, a statistically significant association was found between LBP and cg21149944 methylation (OR = 0.89, 95% CI: 0.82–0.95, p < 0.0015) as well as cg22831726 methylation (OR = 0.9, 95% CI: 0.84–0.96, p < 0.0036). , S. Grègoire (2021) [ ] .

    Techniques: DNA Methylation Assay, Genome Wide, Methylation, Expressing, Methylation Sequencing, Isolation, Enzyme-linked Immunosorbent Assay

    Cytogenetics, cytogenomics, and molecular techniques used to study ring chromosome 20 [r(20)].

    Journal: Frontiers in Neurology

    Article Title: Ring Chromosome 20 Syndrome: Genetics, Clinical Characteristics, and Overlapping Phenotypes

    doi: 10.3389/fneur.2020.613035

    Figure Lengend Snippet: Cytogenetics, cytogenomics, and molecular techniques used to study ring chromosome 20 [r(20)].

    Article Snippet: Array-based genome-wide methylation analysis array (Human Methylation450 BeadChip kit, Illumina) , Evaluation of the methylation level of CpGs in the whole genome in r(20) patients compared to normal controls , Tissue-specific and low-level epimutation mosaicism cannot be detected , Calzari L. [patients from Giardino et al. ( )]; present data ( ) .

    Techniques: Biomarker Discovery, Sequencing, Microarray, Genome Wide, Methylation