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akt inhibitor api 2  (Tocris)


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Bioz Manufacturer Symbol Tocris manufactures this product  
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    Structured Review

    Tocris akt inhibitor api 2
    Akt Inhibitor Api 2, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 45 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/api/API-2/pmc03212871-157-28-31
    Average 93 stars, based on 45 article reviews
    akt inhibitor api 2 - by Bioz Stars, 2026-09
    93/100 stars

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    Related Articles

    other:

    Article Title: Akt activator SC79 stimulates antibacterial nitric oxide production from human nasal epithelial cells and increases macrophage phagocytosis in vitro
    Article Snippet: API-2 was from Tocris.

    Article Title: Akt activator SC79 stimulates antibacterial nitric oxide generation in human nasal epithelial cells in vitro.
    Article Snippet: Funding information NIH, Grant/Award Numbers: R01DC016309, R01AI167971; Cystic Fibrosis Foundation, Grant/Award Number: LEE21G0 Abstract Background: The role of Akt in nasal immunity is unstudied.. Akt phosphorylates and activates endothelial nitric oxide synthase (eNOS) expressed in epithelial ciliated cells.. Nitric oxide (NO) production by ciliated cells can have antibacterial and antiviral effects.

    Article Title: Differential expression of phosphorylated MEK and ERK correlates with aggressive BCC subtypes.
    Article Snippet: Basal cell carcinoma (BCC) is associated with aberrant Hedgehog (HH) signalling through mutational inactivation of PTCH1; however, there is conflicting data regarding MEK/ERK signalling in BCC and the signalling pathway interactions in these carcinomas.. To address this, expression of active phospho (p) MEK and ERK were examined in a panel of 15 non-aggressive and 14 aggressive BCCs.. Although not uniformly expressed, both phospho-proteins were detected in the nuclei and/or cytoplasm of normal and tumour-associated epidermal cells however, whereas pMEK was present in all non-aggressive BCCs (14/14), pERK was rarely expressed (2/14).

    Article Title: In vitro differentiated human CD4 + T cells produce hepatocyte growth factor.
    Article Snippet: PI828 (Tocris, P/N 2814), PP242 (Tocris, P/N 4257), API-2 (triciribine) (Tocris, P/N 2151), Rapamycin (Tocris, P/N 1292).

    Control:

    Article Title: Akt and MAPK/ERK signaling regulate neurite extension in adult neural progenitor cells but do not directly mediate disruption of cytoskeletal structure and neurite dynamics by low-level silver nanoparticles.
    Article Snippet: Silver nanoparticles (AgNPs) are an environmental contaminant of emerging concern.. Ionic and colloidal silver has long been used for its antimicrobial properties, but with the development of engineered AgNPs, these are increasingly incorporated in the manufacture of nano-enhanced products.. AgNPs are released into the environment from manufacturing plants and they can be shed from products during use and after disposal.



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