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pin1 inhibitor api 1  (Selleck Chemicals)


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    Structured Review

    Selleck Chemicals pin1 inhibitor api 1
    Pin1 Inhibitor Api 1, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/api+1/API-1/pm37473892-53-18-21
    Average 91 stars, based on 3 article reviews
    pin1 inhibitor api 1 - by Bioz Stars, 2026-10
    91/100 stars

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    Related Articles

    other:

    Article Title: Prolyl isomerase 1 inhibitor can enhance the efficacy of programmed cell death ligand 1 blockade in triple-negative breast cancer
    Article Snippet: API-1 (Cat. No. S6893; Selleck Chemicals, Houston, TX, USA), a Pin1 inhibitor, was dissolved in dimethyl sulfoxide (DMSO) to prepare a stock solution and diluted with vehicle immediately before use.

    In Vitro:

    Article Title: Pin1 inhibitor API-1 sensitizes BRAF-mutant thyroid cancers to BRAF inhibitors by attenuating HER3-mediated feedback activation of MAPK/ERK and PI3K/AKT pathways.
    Article Snippet: BRAFV600E mutation is one of the most therapeutic targets in thyroid cancers.. However, its specific inhibitors have shown little clinical benefit because they can reactivate the MAPK/ERK and PI3K/AKT pathways by feedback upregulating the transcription of HER3.. Peptidyl-prolyl cis/trans isomerase Pin1 has been proven to be closely associated with tumor progression.



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