antibody microarray (Kinexus Bioinformatics Corporation)
86
Structured Review
Kinexus Bioinformatics Corporation
antibody microarray
Antibody Microarray, supplied by Kinexus Bioinformatics Corporation, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antibody+microarray/antibody+microarray/pmc13043088-153-35-46
Average 86 stars, based on 1 article reviews
Antibody Microarray, supplied by Kinexus Bioinformatics Corporation, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antibody+microarray/antibody+microarray/pmc13043088-153-35-46
Average 86 stars, based on 1 article reviews
antibody microarray - by Bioz Stars,
2026-10
86/100 stars
Images
1) Product Images from "Targeting PI3K γ anchoring enhances CFTR membrane localization and modulator efficacy via PKD1"
Article Title: Targeting PI3K γ anchoring enhances CFTR membrane localization and modulator efficacy via PKD1
Journal: JCI Insight
doi: 10.1172/jci.insight.198846
Figure Legend Snippet: ( A ) Experimental workflow used for phosphoproteomic analysis of F508del-CFBE41o- cells treated with control peptide (CP) or PI3Kγ MP (25 μM, 30 minutes). A phospho-specific microarray, containing 875 phosphosite-specific and 451 pan-specific antibodies, was used. Thirty-six proteins showing phosphorylation changes exceeding ±60% compared with the control (expressed as percentage CFC, i.e., percentage fold-change compared with control) were selected for downstream analysis. ( B and C ) Panther Gene Ontology (GO) slim-term enrichment analysis of proteins with altered phosphorylation after PI3Kγ MP treatment. Significantly enriched GO terms (FDR < 0.05) were categorized under ( B ) biological processes and ( C ) cellular components. ( D ) Reactome pathway enrichment analysis of differentially phosphorylated proteins after PI3Kγ MP treatment. Lines represent the top 20 pathways; x axis shows the –log 10 (FDR). Color intensity reflects fold enrichment, and circle size indicates the number of proteins; color intensity (yellow to red) indicates increasing fold enrichment. The full phospho-array protein list served as background reference. ( E ) Proteins with CFC greater than 60% (green) or less than −60% (red). A CFC of 100% corresponds to a 2-fold increase in signal intensity after PI3Kγ MP treatment relative to CP.
Techniques Used: Control, Microarray, Phospho-proteomics
Related Articles
Expressing:Article Title: Ablation of SGK1 Impairs Endothelial Cell Migration and Tube Formation Leading to Decreased Neo-Angiogenesis Following Myocardial Infarction Article Snippet: .. To investigate whether deletion of SGK1 was involved in regulating other downstream targets, we performed proteomic analyses by assessing the expression and phosphrylation profile of 850 different proteins using a MicroChIP Assay:Article Title: Ablation of SGK1 Impairs Endothelial Cell Migration and Tube Formation Leading to Decreased Neo-Angiogenesis Following Myocardial Infarction Article Snippet: .. To investigate whether deletion of SGK1 was involved in regulating other downstream targets, we performed proteomic analyses by assessing the expression and phosphrylation profile of 850 different proteins using a Microarray:Article Title: Plant phenolics inhibit focal adhesion kinase and suppress host cell invasion by uropathogenic Escherichia coli . Article Snippet: Traditional folk treatments for the prevention and management of urinary tract infections (UTIs) and other infectious diseases often include plants and plant extracts that are rich in phenolic compounds.. These have been ascribed a variety of activities, including inhibition of bacterial interactions with host cells.. Here, we tested a panel of four well-studied phenolic compounds—caffeic acid phenethyl ester (CAPE), resveratrol, catechin, and epigallocatechin gallate—for the effects on host cell adherence and invasion by uropathogenic Escherichia coli (UPEC). Article Title: Plant Phenolics Inhibit Focal Adhesion Kinase and Suppress Host Cell Invasion by Uropathogenic Escherichia coli Article Snippet: .. To examine phenolic effects on host signaling processes that might affect UPEC entry into BECs, we utilized an Article Title: Targeting PI3K γ anchoring enhances CFTR membrane localization and modulator efficacy via PKD1 Article Snippet: .. After treatment with 25 μM PI3Kγ MP or an equimolar amount of CP for 30 minutes, F508del-CFBE41o- cells were lysed as described above, and protein samples were frozen at –80°C before being subjected to an other:Article Title: A triple serine motif in the intracellular domain of SorCS2 impacts its cellular signaling Article Snippet: To understand the mechanistic role of SorCS2 in BDNF/TrkB signaling, we stimulated WT and Sorcs2 KO hippocampal neurons at DIV5 for 10 min with Article Title: A triple serine motif in the intracellular domain of SorCS2 impacts its cellular signaling. Article Snippet: SorCS2 is important for BDNF-induced MAPK pathway activation To understand the mechanistic role of SorCS2 in BDNF/TrkB signaling, we stimulated WT and Sorcs2 KO hippocampal neurons at DIV5 for 10 min with Phospho-proteomics:Article Title: Plant Phenolics Inhibit Focal Adhesion Kinase and Suppress Host Cell Invasion by Uropathogenic Escherichia coli Article Snippet: .. To examine phenolic effects on host signaling processes that might affect UPEC entry into BECs, we utilized an Labeling:Article Title: NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes. Article Snippet: In brief ‘‘De Jesus et al. demonstrate that NREP deficiency in human hepatocytes leads to transcriptomic remodeling and metabolic dysregulation, resembling key pathways implicated in NAFLD.. One carbon metabolism emerges as a potential mediator, highlighting NREP as a promising therapeutic target for improving NAFLD pathophysiology.. These findings provide valuable insights into the molecular mechanisms underlying NAFLD progression.’’. |
