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tse shuttle box, active & passive avoidance system  (TSE systems)


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    TSE systems tse shuttle box, active & passive avoidance system
    Tse Shuttle Box, Active & Passive Avoidance System, supplied by TSE systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/active+avoidance+boxes/tse+shuttle+box++active+++passive+avoidance+system/pm33127363-146-30-33
    Average 90 stars, based on 1 article reviews
    tse shuttle box, active & passive avoidance system - by Bioz Stars, 2026-10
    90/100 stars

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    Article Snippet: α7 nicotinic acetylcholine receptor (α7 nAChR) is an extensively validated target for several neurological and psychiatric conditions namely, dementia and schizophrenia, owing to its vital roles in cognition and sensorimotor gating.. Positive allosteric modulation (PAM) of α7 nAChR represents an innovative approach to amplify endogenous cholinergic signaling in a temporally restricted manner in learning and memory centers of brain. α7 nAChR PAMs are anticipated to side-step burgeoning issues observed with several clinical-stage orthosteric α7 nAChR agonists, related to selectivity, tolerance/tachyphylaxis, thus providing a novel dimension in therapeutic strategy and pharmacology of α7 nAChR ion-channel.. Here we describe a novel α7 nAChR PAM, LL-00066471, which potently amplified agonist-induced Ca2+ fluxes in neuronal IMR-32 neuroblastoma cells in a α-bungarotoxin (α-BTX) sensitive manner.



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