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l9-3 linear array transducer  (Philips Healthcare)

 
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    Structured Review

    Philips Healthcare l9-3 linear array transducer
    L9 3 Linear Array Transducer, supplied by Philips Healthcare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/3/hdi+5000/nct03436875-44-12-19
    Average 90 stars, based on 1 article reviews
    l9-3 linear array transducer - by Bioz Stars, 2026-11
    90/100 stars

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    Related Articles

    other:

    Article Title: Spectroscopic photoacoustic denoising framework using hybrid analytical and data-free learning method
    Article Snippet: A linear transducer (L12–5, Philips, Netherlands) facilitated both US and PA imaging.

    Article Title: Ultrasound-guided high-voltage pulsed radiofrequency versus standard-voltage pulsed radiofrequency in refractory chronic cervical radicular pain randomized clinical trial.
    Article Snippet: A 12-MHz high-frequency linear transducer (Philips Ultrasound machine-USA) was employed, with a lubricating gel applied between the transducer and the skin to ensure clear imaging by eliminating air bubbles.

    Article Title: Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With Psoriatic Arthritis - a Pilot Randomized Controlled Trial
    Article Snippet: Measure Description: Carotid plaques will be assessed at baseline and 12 months using a high-resolution B mode ultrasound machine (Philips EPIQ7) by a single experienced sonographer blinded to all clinical information using a 30-MHz linear vascular probe (Philips L12-3 broadband linear array transducer).

    Article Title: Cardiometabolic Health in Adult Latinos in the Rio Grande Valley With and Without Specific Gene Mutations
    Article Snippet: Brachial artery diameter and blood flow velocity will be determined proximal to the antecubital fold using a high frequency L12-5 linear array transducer interfaced to an iU22 ultrasound (Philips Medical Systems).

    Article Title: Rib-indexed quantitative lung ultrasound versus chest X-ray for lung recruitment assessment in neonates with moderate-severe ARDS on surfactant therapy combined with prone position: a prospective observational study
    Article Snippet: Ultrasonography was conducted using a Philips CX50 system (Bothell, WA) equipped with an L12-3 broadband linear transducer operating on neonatal presets.

    Article Title: Novel biomarker panel combined with imaging parameters for predicting cardiovascular complications in diabetic patients: a retrospective cohort study.
    Article Snippet: Carotid Plaque Characteristics: Assessed via high-resolution ultrasound (Philips EPIQ 7G system, L12-5 linear array probe, frequency range: 5–12 MHz) or CT angiography (Siemens SOMATOM Force; contrast-enhanced protocol, 0.625 mm slice thickness, reconstruction kernel: Bv40).

    Article Title: Molecular insights into the relationship between sustained CRP elevation and endothelial dysfunction in axial spondyloarthritis.
    Article Snippet: Carotid ultrasound was performed by an expert radiologist with a Philips Epiq- 7 system and a 5–14 MHz broadband linear transducer using B- mode, duplex and colour methods.

    Imaging:

    Article Title: Cardiometabolic Health in Adult Latinos in the Rio Grande Valley With and Without Specific Gene Mutations
    Article Snippet: .. CEU imaging of forearm muscle will be performed using an L9-3 linear array transducer interfaced to an iU22 ultrasound (Philips) during microbubble (Lumison®) infusion as described previously \[17, 18\]. .. CEU images will be analysed off-line using Qlab (Version 10.8, Philips) to determine microvascular blood volume (A), microvascular flow velocity (β) and microvascular perfusion (A×β) as done previously by the PI.



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    Factors influencing the exhausted state of NK cells. The exhaustion of NK cells in the TME is regulated by multiple factors which results in NK cell function impairment due to: the downregulated expression of NK cell-activating receptors (e.g., NKG2D, DNAM-1, NKp30), the reduced secretion of effector cytokines (such as IFN-γ), and the upregulated expression of immunosuppressive molecules (e.g., PD-1, NKG2A, TIGIT, CD96, TIM-3, LAG-3). Additionally, transforming growth factor-β (TGF-β) secreted by tumor cells, cancer-associated fibroblasts (CAFs), and extracellular vesicles (EVs); hypoxic microenvironment; indoleamine 2,3-dioxygenase (IDO); prostaglandin E2 (PGE2); and immunosuppressive cells including macrophages, regulatory T cells (Treg), and myeloid-derived suppressor cells (MDSC) are involved in regulating NK cell exhaustion through multiple pathways.

    Journal: Pharmaceutical Science Advances

    Article Title: Mechanisms of tumor cell evasion from NK cell-mediated killing and advances in NK cell-based cancer immunotherapy

    doi: 10.1016/j.pscia.2026.100109

    Figure Lengend Snippet: Factors influencing the exhausted state of NK cells. The exhaustion of NK cells in the TME is regulated by multiple factors which results in NK cell function impairment due to: the downregulated expression of NK cell-activating receptors (e.g., NKG2D, DNAM-1, NKp30), the reduced secretion of effector cytokines (such as IFN-γ), and the upregulated expression of immunosuppressive molecules (e.g., PD-1, NKG2A, TIGIT, CD96, TIM-3, LAG-3). Additionally, transforming growth factor-β (TGF-β) secreted by tumor cells, cancer-associated fibroblasts (CAFs), and extracellular vesicles (EVs); hypoxic microenvironment; indoleamine 2,3-dioxygenase (IDO); prostaglandin E2 (PGE2); and immunosuppressive cells including macrophages, regulatory T cells (Treg), and myeloid-derived suppressor cells (MDSC) are involved in regulating NK cell exhaustion through multiple pathways.

    Article Snippet: TIM-3 ligands-including Galectin-9, PS, HMGB1, and CEACAM-1-play crucial roles in regulating NK activity.

    Techniques: Cell Function Assay, Expressing, Derivative Assay

    Strategies for enhancing NK cell anti-tumor activity. The anti-tumor efficacy of NK cells can be improved through multiple approaches: Adoptive NK cell infusions, including autologous NK cells (combined with HAIC), allogeneic NK cells (with high potential), and infusions with or without allogeneic transplantation; NK cell checkpoint inhibitors targeting molecules such as PD-1/PD-L1, KIRs (KIR2DL1/2/3/5), NKG2A/CD94, TIM-3, and LAG-3; Advanced applications of CAR-NK cells, including IL-15-secreting CAR-NK cell therapy targeting mesothelin, TIPE2 gene-knockout CAR-NK therapy, and application of modified CCCR-NK92; Administration of stimulatory cytokines like IL-2, IL-15, IL-18, and IL-21; Bi or trispecific killer engagers, including Bispecific antibody: LB1410 (anti-PD-1/TIM-3) and trispecific nanobody: PDL1/PD-1/NKG2A.

    Journal: Pharmaceutical Science Advances

    Article Title: Mechanisms of tumor cell evasion from NK cell-mediated killing and advances in NK cell-based cancer immunotherapy

    doi: 10.1016/j.pscia.2026.100109

    Figure Lengend Snippet: Strategies for enhancing NK cell anti-tumor activity. The anti-tumor efficacy of NK cells can be improved through multiple approaches: Adoptive NK cell infusions, including autologous NK cells (combined with HAIC), allogeneic NK cells (with high potential), and infusions with or without allogeneic transplantation; NK cell checkpoint inhibitors targeting molecules such as PD-1/PD-L1, KIRs (KIR2DL1/2/3/5), NKG2A/CD94, TIM-3, and LAG-3; Advanced applications of CAR-NK cells, including IL-15-secreting CAR-NK cell therapy targeting mesothelin, TIPE2 gene-knockout CAR-NK therapy, and application of modified CCCR-NK92; Administration of stimulatory cytokines like IL-2, IL-15, IL-18, and IL-21; Bi or trispecific killer engagers, including Bispecific antibody: LB1410 (anti-PD-1/TIM-3) and trispecific nanobody: PDL1/PD-1/NKG2A.

    Article Snippet: TIM-3 ligands-including Galectin-9, PS, HMGB1, and CEACAM-1-play crucial roles in regulating NK activity.

    Techniques: Activity Assay, Transplantation Assay, Gene Knockout, Modification