3-carbamoyl-proxyl (cmp (Millipore)
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3-carbamoyl-proxyl (cmp
3 Carbamoyl Proxyl (Cmp, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/3+cmp/3+carbamoylproxyl/pmc10758964-57-2-4
Average 90 stars, based on 1 article reviews
3 Carbamoyl Proxyl (Cmp, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/3+cmp/3+carbamoylproxyl/pmc10758964-57-2-4
Average 90 stars, based on 1 article reviews
3-carbamoyl-proxyl (cmp - by Bioz Stars,
2026-10
90/100 stars
Images
1) Product Images from "Non-invasive differentiation of hepatic steatosis and steatohepatitis in a mouse model using nitroxyl radical as an MRI-contrast agent"
Article Title: Non-invasive differentiation of hepatic steatosis and steatohepatitis in a mouse model using nitroxyl radical as an MRI-contrast agent
Journal: Toxicology Reports
doi: 10.1016/j.toxrep.2023.12.002
Figure Legend Snippet: Phantom images. (A) T1-weighted phantom image with 3-Carbamoyl-PROXYL (0–50 mM). (B) The mean contrast to noise ratios (CNRs) increased with increasing dose. The doses plotted are the same as in A. The mean CNRs at ≥ 1 mM exceeded 5 and meets the definition that is apparently distinguishable from background.
Techniques Used:
Figure Legend Snippet: T1-weighted sequential images with 3-Carbamoyl-PROXYL (CmP) and its analysis in the liver. (A) Typical T1-weighted sequential images with CmP. From the left, images are of the control liver, steatotic liver, and steatohepatitic liver (NAS of 3). Circle indicates region of interest. Hyperintensity of the liver in T1-weighted MRI was lost earlier in the steatohepatitic liver (NAS of 3) than in the control liver and steatotic liver. (B) Images show the reduction rate per pixel for three mice in A. White and black, the extremes of the color spectrum, represent the highest and lowest reduction rate, respectively. The color of the whole liver is mostly yellowish green in the steatohepatitic liver (NAS of 3), while it is mostly light blue in the control liver and steatotic liver. It showed that the reduction rate in the steatohepatitic liver (NAS of 3) was higher than in the other two. (C) The graph shows the sequential signal intensity change rate in the liver. Semilogarithmic plots of signal intensity change rate in the control liver (squares), steatotic liver (crosses), and steatohepatitic liver (NAS of 3; circles). The reduction rate was obtained from the slope of the linear regression line, and the range of data used for analysis is indicated by blue, green, and yellow dot plots. The graph shows that the slope was higher in steatohepatitic liver (NAS of 3) than in the control liver and steatotic liver. (D) The vertical dot plot shows a significantly higher reduction rate in the liver in the steatohepatitis (NAS of 3) group than in other groups. Significantly different from the control group: **p < 0.01, from the hepatic steatosis group: †† p < 0.01, and from the steatohepatitis group (NAS of 2): ‡‡ p < 0.01 (Dunnett’s test). Bars indicate the mean values.
Techniques Used:
Related Articles
other:Article Title: Non-invasive differentiation of hepatic steatosis and steatohepatitis in a mouse model using nitroxyl radical as an MRI-contrast agent Article Snippet: We selected Article Title: In vivo measurement of redox status in streptozotocin-induced diabetic rat using targeted nitroxyl probes. Article Snippet: In vivo electron paramagnetic resonance (EPR) with nitroxyl spin probes has been used for the evaluation of in vivo free radical reactions and redox status in living animals.. The aim of this study was to clarify the location of free radical reactions induced by hyperglycemia in osteogenic disorder shionogi (ODS) rats using in vivo EPR spectroscopy.. Diabetes was induced by intravenous injection of streptozotocin (STZ). |