sacubitril Search Results


lcz696  (MedChemExpress)
93
MedChemExpress lcz696
Effect of <t>LCZ696</t> on cardiac function and survival rate (A) Typical M‐mode echocardiograms of the long‐axis midventricular view and HR, LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.
Lcz696, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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sacubitril calcium salt arni  (Tocris)
92
Tocris sacubitril calcium salt arni
Effect of <t>LCZ696</t> on cardiac function and survival rate (A) Typical M‐mode echocardiograms of the long‐axis midventricular view and HR, LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.
Sacubitril Calcium Salt Arni, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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medchemexpress llc  (MedChemExpress)
93
MedChemExpress medchemexpress llc
Effect of <t>LCZ696</t> on cardiac function and survival rate (A) Typical M‐mode echocardiograms of the long‐axis midventricular view and HR, LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.
Medchemexpress Llc, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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lcz696  (Selleck Chemicals)
93
Selleck Chemicals lcz696
Effect of <t>LCZ696</t> on cardiac function and survival rate (A) Typical M‐mode echocardiograms of the long‐axis midventricular view and HR, LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.
Lcz696, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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valsartan  (TargetMol)
91
TargetMol valsartan
Effect of <t>LCZ696</t> on cardiac function and survival rate (A) Typical M‐mode echocardiograms of the long‐axis midventricular view and HR, LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.
Valsartan, supplied by TargetMol, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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15407a cs  (MedChemExpress)
92
MedChemExpress 15407a cs

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sacubitril sac  (MedChemExpress)
93
MedChemExpress sacubitril sac

Sacubitril Sac, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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sacubitril  (MedChemExpress)
92
MedChemExpress sacubitril

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sacubitril  (MuseChem Chemicals)
90
MuseChem Chemicals sacubitril

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monosodium sacubitril and disodium valsartan cocrystal  (Novartis)
90
Novartis monosodium sacubitril and disodium valsartan cocrystal

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sacubitril/valsartan  (HealthCore Inc)
90
HealthCore Inc sacubitril/valsartan

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sacubitril/valsartan  (Novartis)
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Novartis sacubitril/valsartan

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Image Search Results


Effect of LCZ696 on cardiac function and survival rate (A) Typical M‐mode echocardiograms of the long‐axis midventricular view and HR, LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.

Journal: ESC Heart Failure

Article Title: The protective effect of LCZ696 in coxsackievirus B3‐induced acute viral myocarditis mice

doi: 10.1002/ehf2.14194

Figure Lengend Snippet: Effect of LCZ696 on cardiac function and survival rate (A) Typical M‐mode echocardiograms of the long‐axis midventricular view and HR, LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.

Article Snippet: LCZ696 (MCE, USA, 60 mg/kg/d) was administered from d1 to d7, the same volume of saline as control.

Techniques:

Effect of LCZ696 on anti‐inflammation and anti‐apoptosis. (A) Cardiac inflammation revealed by HE staining (magnification: 40× and 100×). (B) IHC of IL‐6 in each group (magnification: 200×). (C) TUNEL staining in myocardial tissue of each group (magnification: 200×). (D) The absolute intensity ratio of pro‐inflammatory cytokines and c‐caspase‐3/caspase‐3 ( n = 6 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.

Journal: ESC Heart Failure

Article Title: The protective effect of LCZ696 in coxsackievirus B3‐induced acute viral myocarditis mice

doi: 10.1002/ehf2.14194

Figure Lengend Snippet: Effect of LCZ696 on anti‐inflammation and anti‐apoptosis. (A) Cardiac inflammation revealed by HE staining (magnification: 40× and 100×). (B) IHC of IL‐6 in each group (magnification: 200×). (C) TUNEL staining in myocardial tissue of each group (magnification: 200×). (D) The absolute intensity ratio of pro‐inflammatory cytokines and c‐caspase‐3/caspase‐3 ( n = 6 in each group). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.

Article Snippet: LCZ696 (MCE, USA, 60 mg/kg/d) was administered from d1 to d7, the same volume of saline as control.

Techniques: Staining, TUNEL Assay

Effect of LCZ696 on mitochondrial fission. (A) The morphology and structure of mitochondria in the myocardium of each group were detected by transmission electron microscopy (magnification: 15 000× and 150 000×). (B) The absolute intensity ratio of p‐Drp1/Drp1 and Drp1/GAPDH ( n = 6 in each group). (C) IHC of p‐Drp1 in each group (magnification: 100×). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.

Journal: ESC Heart Failure

Article Title: The protective effect of LCZ696 in coxsackievirus B3‐induced acute viral myocarditis mice

doi: 10.1002/ehf2.14194

Figure Lengend Snippet: Effect of LCZ696 on mitochondrial fission. (A) The morphology and structure of mitochondria in the myocardium of each group were detected by transmission electron microscopy (magnification: 15 000× and 150 000×). (B) The absolute intensity ratio of p‐Drp1/Drp1 and Drp1/GAPDH ( n = 6 in each group). (C) IHC of p‐Drp1 in each group (magnification: 100×). Results were presented as the mean ± SD. * P < 0.05 vs. Sham group; # P < 0.05 vs. AVMC group.

Article Snippet: LCZ696 (MCE, USA, 60 mg/kg/d) was administered from d1 to d7, the same volume of saline as control.

Techniques: Transmission Assay, Electron Microscopy, Paraffin-embedded Immunohistochemistry

Effect of Drp1 overexpression on cardiac function and survival rate. (A) Typical M‐mode echocardiograms of the long‐axis midventricular view, HR and LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). (C) IF of the GFP contained by AAV in the AVMC + AAV and AVMC + LCZ696 + AAV group (magnification: 200×). Results were presented as the mean ± SD. * P < 0.05 vs. AVMC group; # P < 0.05 vs. AVMC + AAV group; & P < 0.05 vs. AVMC + LCZ696 group.

Journal: ESC Heart Failure

Article Title: The protective effect of LCZ696 in coxsackievirus B3‐induced acute viral myocarditis mice

doi: 10.1002/ehf2.14194

Figure Lengend Snippet: Effect of Drp1 overexpression on cardiac function and survival rate. (A) Typical M‐mode echocardiograms of the long‐axis midventricular view, HR and LVIDd, LVIDs, and LVEF ( n = 9 in each group). (B) The survival rate was measured every day until d7 ( n = 20 in each group). (C) IF of the GFP contained by AAV in the AVMC + AAV and AVMC + LCZ696 + AAV group (magnification: 200×). Results were presented as the mean ± SD. * P < 0.05 vs. AVMC group; # P < 0.05 vs. AVMC + AAV group; & P < 0.05 vs. AVMC + LCZ696 group.

Article Snippet: LCZ696 (MCE, USA, 60 mg/kg/d) was administered from d1 to d7, the same volume of saline as control.

Techniques: Over Expression

Effect of Drp1 overexpression on mitochondria. (A) The morphology and structure of mitochondria in the myocardium of each group were detected by transmission electron microscopy (magnification: 15 000× and 150 000×). (B) The absolute intensity ratio of p‐Drp1/Drp1 ( n = 6 in each group). (C) IHC of p‐Drp1 in each group (magnification: 100×). Results were presented as the mean ± SD. * P < 0.05 vs. AVMC group; # P < 0.05 vs. AVMC + AAV group; & P < 0.05 vs. AVMC + LCZ696 group. & P < 0.05 vs. AVMC + LCZ696 group.

Journal: ESC Heart Failure

Article Title: The protective effect of LCZ696 in coxsackievirus B3‐induced acute viral myocarditis mice

doi: 10.1002/ehf2.14194

Figure Lengend Snippet: Effect of Drp1 overexpression on mitochondria. (A) The morphology and structure of mitochondria in the myocardium of each group were detected by transmission electron microscopy (magnification: 15 000× and 150 000×). (B) The absolute intensity ratio of p‐Drp1/Drp1 ( n = 6 in each group). (C) IHC of p‐Drp1 in each group (magnification: 100×). Results were presented as the mean ± SD. * P < 0.05 vs. AVMC group; # P < 0.05 vs. AVMC + AAV group; & P < 0.05 vs. AVMC + LCZ696 group. & P < 0.05 vs. AVMC + LCZ696 group.

Article Snippet: LCZ696 (MCE, USA, 60 mg/kg/d) was administered from d1 to d7, the same volume of saline as control.

Techniques: Over Expression, Transmission Assay, Electron Microscopy, Paraffin-embedded Immunohistochemistry

Effect of Drp1 overexpression on inflammation and apoptosis. (A) Cardiac inflammation revealed by HE staining (magnification: 40× and 100×). (B) IHC of IL‐6 (magnification: 200×). (C) TUNEL staining in myocardial tissue (magnification: 200×). (D) The ratio of IL‐6, c‐IL‐1β, and c‐caspase‐3/caspase‐3. * P < 0.05 vs. AVMC group; # P < 0.05 vs. AVMC + AAV group; & P < 0.05 vs. AVMC + LCZ696 group.

Journal: ESC Heart Failure

Article Title: The protective effect of LCZ696 in coxsackievirus B3‐induced acute viral myocarditis mice

doi: 10.1002/ehf2.14194

Figure Lengend Snippet: Effect of Drp1 overexpression on inflammation and apoptosis. (A) Cardiac inflammation revealed by HE staining (magnification: 40× and 100×). (B) IHC of IL‐6 (magnification: 200×). (C) TUNEL staining in myocardial tissue (magnification: 200×). (D) The ratio of IL‐6, c‐IL‐1β, and c‐caspase‐3/caspase‐3. * P < 0.05 vs. AVMC group; # P < 0.05 vs. AVMC + AAV group; & P < 0.05 vs. AVMC + LCZ696 group.

Article Snippet: LCZ696 (MCE, USA, 60 mg/kg/d) was administered from d1 to d7, the same volume of saline as control.

Techniques: Over Expression, Staining, TUNEL Assay

Journal: Cell Reports

Article Title: Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1

doi: 10.1016/j.celrep.2023.112059

Figure Lengend Snippet:

Article Snippet: Sacubitril , MedChemExpress , CatHY-15407A/CS-2514.Batch n°:15499.

Techniques: Recombinant, Enzyme-linked Immunosorbent Assay, Software