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m100907  (MedChemExpress)
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MedChemExpress m100907
Economic demand parameters from fentanyl demand sessions with DOI and/or <t>M100907</t> administration. A) Timeline of 5HT2A agonist/antagonist testing phase. B) Example saline and 0.4mg/kg DOI curves from a single rat. C-F) Log2 fold-change in indicated economic demand parameter for each drug condition relative to the log-average of all vehicle sessions. DOI 0.1mg/kg (N=10), 0.2mg/kg (N=10), 0.4 mg/kg (N=7), M100907 + DOI (N=5), M100907 alone (N=5). “*” = p<.05, “**” = p<.01, “***” = p<.001, Results of Dunnet’s post-hoc test, compared to vehicle, following significant ANOVA overall effect (p<.05).
M100907, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Economic demand parameters from fentanyl demand sessions with DOI and/or M100907 administration. A) Timeline of 5HT2A agonist/antagonist testing phase. B) Example saline and 0.4mg/kg DOI curves from a single rat. C-F) Log2 fold-change in indicated economic demand parameter for each drug condition relative to the log-average of all vehicle sessions. DOI 0.1mg/kg (N=10), 0.2mg/kg (N=10), 0.4 mg/kg (N=7), M100907 + DOI (N=5), M100907 alone (N=5). “*” = p<.05, “**” = p<.01, “***” = p<.001, Results of Dunnet’s post-hoc test, compared to vehicle, following significant ANOVA overall effect (p<.05).

Journal: Addiction biology

Article Title: Effects of 5-HT 2A Receptor Stimulation on Economic Demand for Fentanyl after Intermittent and Continuous Access Self-Administration in Male Rats

doi: 10.1111/adb.12926

Figure Lengend Snippet: Economic demand parameters from fentanyl demand sessions with DOI and/or M100907 administration. A) Timeline of 5HT2A agonist/antagonist testing phase. B) Example saline and 0.4mg/kg DOI curves from a single rat. C-F) Log2 fold-change in indicated economic demand parameter for each drug condition relative to the log-average of all vehicle sessions. DOI 0.1mg/kg (N=10), 0.2mg/kg (N=10), 0.4 mg/kg (N=7), M100907 + DOI (N=5), M100907 alone (N=5). “*” = p<.05, “**” = p<.01, “***” = p<.001, Results of Dunnet’s post-hoc test, compared to vehicle, following significant ANOVA overall effect (p<.05).

Article Snippet: We obtained M100907 from MedChem Express and dissolved it in absolute ethanol (1mg/100μl), followed by the addition of emulphur oils at equal volume.

Techniques: Saline