HY-127079 Search Results


piribedil  (MedChemExpress)
91
MedChemExpress piribedil
a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and <t>Piribedil.</t> Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .
Piribedil, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/piribedil/product/MedChemExpress
Average 91 stars, based on 1 article reviews
piribedil - by Bioz Stars, 2026-02
91/100 stars
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a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and Piribedil. Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .

Journal: Nature Genetics

Article Title: Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes

doi: 10.1038/s41588-025-02409-6

Figure Lengend Snippet: a , Genome browser snapshots from four species, with genomic coordinates indicated at the top. RNA-seq (displayed for both positive and negative strands) and ChIP–seq datasets are normalized using reads per million (RPM). Non-stranded RNA-seq data are shown as a single track. For Chlamydomonas reinhardtii , RNA polymerase II ChIP–seq data are also displayed. b , Western blot analysis showing total histone H3 and H3K4me3 modifications in A. castellanii cells treated with the H3K4me3 inhibitors OICR-9429 and Piribedil. Equal amounts of total protein were loaded in each well. This experiment was repeated twice. c , Average 6mA at ApT (%) levels measured on H3K4me3 peaks in wild-type cells, comparing OICR-9429 treatment versus control and Piribedil versus control. DMSO concentrations for controls are matched to the final DMSO levels in the inhibitor samples. d , Global 6mA at ApT (%) levels in each sample as described in c .

Article Snippet: Histone H3K4me3 suppression drugs OICR-9424 (MedChemExpress, HY-16993) and Piribedil (Cayman Chemical, 3605-01-4) were diluted in DMSO at 50 mM and 100 mM, respectively, as stock solutions.

Techniques: RNA Sequencing, ChIP-sequencing, Western Blot, Control