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Image Search Results
Journal: bioRxiv
Article Title: Parallel use of pluripotent human stem cell lung and heart models provide new insights for treatment of SARS-CoV-2
doi: 10.1101/2022.09.20.508614
Figure Lengend Snippet: (A) Virus titer in supernatants from SARS-CoV-2 (VIC01) infected H9- derived WT and ACE2 KO cardiac and lung AT2 cells. (B) Virus titer at 3 dpi in supernatants from lung AT2 (H9) and cardiac cells (NKX2-5) treated with two α-ACE2 antibodies or a human IgG1 isotype control before infection with SARS-CoV-2. (C) Virus titer at 3 dpi in supernatant from cardiac cells (red triangles) and lung AT2 cells (blue squares) infected with SARS-CoV-2 (VIC01) in the presence of Camostat, CA-074 or DMSO (vehicle control). Virus titres and genome copies at 3 dpi in supernatant from Vero, lung AT2 and cardiac cells infected with SARS-CoV-2 VIC01 in the presence of various concentrations of Remdesivir (D) or NHC (E).
Article Snippet:
Techniques: Infection, Derivative Assay
Journal: bioRxiv
Article Title: Parallel use of pluripotent human stem cell lung and heart models provide new insights for treatment of SARS-CoV-2
doi: 10.1101/2022.09.20.508614
Figure Lengend Snippet: (A) Cell viability in uninfected Vero, lung AT2 and cardiac cells following 3 days culture in the presence of Remdesivir or NHC at the indicated concentrations. (B) Virus titer and viral genome copies in the supernatant at 3 dpi in Vero, lung AT2, NKX2- 5 cardiac and ALP3K KO cells infected with SARS-CoV-2 in the presence of 1µM or 10µM Favipiravir, Chloroquine, Tizoxanide or Piperaquine. Cell viability of uninfected cells after 3 days culture in the presence of the above drugs.
Article Snippet:
Techniques: Infection