Review





Similar Products

rym 1  (MedChemExpress)
93
MedChemExpress rym 1
Rym 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rym 1/product/MedChemExpress
Average 93 stars, based on 1 article reviews
rym 1 - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
mouse chil1  (R&D Systems)
91
R&D Systems mouse chil1
Mouse Chil1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse chil1/product/R&D Systems
Average 91 stars, based on 1 article reviews
mouse chil1 - by Bioz Stars, 2026-05
91/100 stars
  Buy from Supplier
ym1 chi3l3  (R&D Systems)
93
R&D Systems ym1 chi3l3
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Ym1 Chi3l3, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ym1 chi3l3/product/R&D Systems
Average 93 stars, based on 1 article reviews
ym1 chi3l3 - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
ym1  (Pasteur Institute)
86
Pasteur Institute ym1
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Ym1, supplied by Pasteur Institute, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ym1/product/Pasteur Institute
Average 86 stars, based on 1 article reviews
ym1 - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier
mouse chi3l3 elisa kit picokine  (Boster Bio)
93
Boster Bio mouse chi3l3 elisa kit picokine
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Mouse Chi3l3 Elisa Kit Picokine, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse chi3l3 elisa kit picokine/product/Boster Bio
Average 93 stars, based on 1 article reviews
mouse chi3l3 elisa kit picokine - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
ek2010 piercetm cell surface protein biotinylation  (Boster Bio)
93
Boster Bio ek2010 piercetm cell surface protein biotinylation
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Ek2010 Piercetm Cell Surface Protein Biotinylation, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ek2010 piercetm cell surface protein biotinylation/product/Boster Bio
Average 93 stars, based on 1 article reviews
ek2010 piercetm cell surface protein biotinylation - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
mkk100 chi3l3 elisa kit picokine boster bio  (Boster Bio)
93
Boster Bio mkk100 chi3l3 elisa kit picokine boster bio
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Mkk100 Chi3l3 Elisa Kit Picokine Boster Bio, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mkk100 chi3l3 elisa kit picokine boster bio/product/Boster Bio
Average 93 stars, based on 1 article reviews
mkk100 chi3l3 elisa kit picokine boster bio - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
anti chia ym1  (Proteintech)
93
Proteintech anti chia ym1
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Anti Chia Ym1, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti chia ym1/product/Proteintech
Average 93 stars, based on 1 article reviews
anti chia ym1 - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
goat anti ym1  (R&D Systems)
93
R&D Systems goat anti ym1
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Goat Anti Ym1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/goat anti ym1/product/R&D Systems
Average 93 stars, based on 1 article reviews
goat anti ym1 - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier
biotinylated anti ym1  (R&D Systems)
93
R&D Systems biotinylated anti ym1
(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 <t>(CHI3L3),</t> Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 <t>(CHI3L3),</t> another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.
Biotinylated Anti Ym1, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/biotinylated anti ym1/product/R&D Systems
Average 93 stars, based on 1 article reviews
biotinylated anti ym1 - by Bioz Stars, 2026-05
93/100 stars
  Buy from Supplier

Image Search Results


(A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 (CHI3L3), Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 (CHI3L3), another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.

Journal: bioRxiv

Article Title: Cribriform Plate Microenvironment Assembles a Suppressive Myeloid Network during EAE-induced Neuroinflammation

doi: 10.64898/2026.01.07.698165

Figure Lengend Snippet: (A) Heatmap displaying scaled expression (z-score) of highly expressed representative genes involved in immune regulation, immune activation (e.g., Pdcd1 ) across four cell types: macrophages (MΦ), T cells, migratory dendritic cells (Mig DCs), and fibroblasts (e.g., Pdpn ). Color scale indicates expression levels. (B) Quantification and network map of predicted ligand-receptor interactions between fibroblasts and immune populations (macrophages, Mig DCs, and T cells) using integrated analysis from CellChat, CellPhoneDB, iCellNet, and the Ramilowsky dataset. The bar graph shows the number of unique ligand-receptor interactions per pairwise combination, with the most extensive communication observed between macrophages and fibroblasts. Analyzed with crossTALK IntEraction Network (TALKIEN) with microglia, neutrophils, and proliferating gene sets excluded. (C) Network plot illustrating specific ligand-receptor pairs involved in fibroblast-immune cell communication. Arrows point from ligand-expressing to receptor-expressing cell types. Notable interactions include Spp1-CD44 , Pdpn-Clec2d , and Thbs1-CD47 . (D) Immunofluorescence imaging of the cribriform plate region in EAE day 3.0 mice showing spatial organization of LYVE-1 + lymphatics (white), PDPN + lymphatics and ECM (red), and CSF1R-GFP + myeloid cells (green). DAPI (blue) marks nuclei. Scale bars: 30 µm. (E) Pathway enrichment analysis of ligand-receptor pairs among macrophages, Mig DCs, T cells, and fibroblasts. Enriched pathways include extracellular matrix organization, integrin-mediated interactions, interleukin 10 signaling. Gene ratio represents the proportion of identified genes contributing to each pathway; dot size reflects the number of genes, and color indicates adjusted p-value. (F) : UMAP projection shows major post contact cell types, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Chil3 (CHI3L3), Arg1 , Spp1 , Ccr2 , Cxcr4 , Csf1r (G) : Volcano plot comparing post-contact vs no-contact cluster 2 macrophages (Highest Arg1 expressing cluster). Analysis reveals post contact macrophage have downregulated MHC-II processing and presentation genes ( H2-DMa , H2-Aa , H2-Ab1 , H2-DMb1 , H2-Eb1 , Cd74 , Ciita ) and elevated expression of Chil3 (CHI3L3), another alternatively activated macrophage marker and ECM binding protein. (H) : Gene ontology enrichment analysis (bottom) demonstrates post contact Macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.

Article Snippet: The following antibodies were used for immunohistochemistry: Podoplanin PE (eBioscience, Catalog #: 12-5381-80), CD31 Alexa647 (BD Biosciences, Catalog #: 563608), Lyve-1 eFluor660 (Thermo Fisher Scientific, Catalog #: 50-0443-80), MHC II eFluor450 (eBioscience, Catalog #: 48-5321-80), CD11c Alexa488 (Thermo Fisher Scientific, Catalog #: 53-0114-80), YM1 / CHI3L3 (R&D Systems Catalog #: AF2446), Arginase-1 (Invitrogen, Catalog #: PA5-29645), Cleaved Caspase-3 (Abcam, Catalog #: E83-77) .

Techniques: Expressing, Activation Assay, Immunofluorescence, Imaging, Marker, Binding Assay

UMAP projection (top left) shows major post contact cell types isolated, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Arg1 , Ly6c2 , Ccr2 , Chil3 (CHI3L3), and Pdpn , identifying infiltrating monocyte-derived, alternatively activated macrophages, distinct from T cells ( Cd3e , Ifng ), DCs ( CCR7 , Cd80 ), microglia ( Tmem119 , P2ry12 ), neutrophils ( Ly6g , Cxcr2 ), and proliferating cells ( Mki67 , Top2a ). Gene ontology enrichment analysis (bottom) demonstrates that these post contact macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.

Journal: bioRxiv

Article Title: Cribriform Plate Microenvironment Assembles a Suppressive Myeloid Network during EAE-induced Neuroinflammation

doi: 10.64898/2026.01.07.698165

Figure Lengend Snippet: UMAP projection (top left) shows major post contact cell types isolated, including macrophages (purple), microglia (green), neutrophils (blue), T cells (orange), proliferating cells (light blue), migratory dendritic cells (yellow-orange), and fibroblasts (aqua). Feature plots highlight expression of Arg1 , Ly6c2 , Ccr2 , Chil3 (CHI3L3), and Pdpn , identifying infiltrating monocyte-derived, alternatively activated macrophages, distinct from T cells ( Cd3e , Ifng ), DCs ( CCR7 , Cd80 ), microglia ( Tmem119 , P2ry12 ), neutrophils ( Ly6g , Cxcr2 ), and proliferating cells ( Mki67 , Top2a ). Gene ontology enrichment analysis (bottom) demonstrates that these post contact macrophages are enriched for pathways in Fcγ receptor and complement receptor signaling, negative regulation of IL-12 production, homotypic cell-cell adhesion, and hemostasis.

Article Snippet: The following antibodies were used for immunohistochemistry: Podoplanin PE (eBioscience, Catalog #: 12-5381-80), CD31 Alexa647 (BD Biosciences, Catalog #: 563608), Lyve-1 eFluor660 (Thermo Fisher Scientific, Catalog #: 50-0443-80), MHC II eFluor450 (eBioscience, Catalog #: 48-5321-80), CD11c Alexa488 (Thermo Fisher Scientific, Catalog #: 53-0114-80), YM1 / CHI3L3 (R&D Systems Catalog #: AF2446), Arginase-1 (Invitrogen, Catalog #: PA5-29645), Cleaved Caspase-3 (Abcam, Catalog #: E83-77) .

Techniques: Isolation, Expressing, Derivative Assay