Journal: Cornea

Article Title: Cornea Crosslinking with Verteporfin and Non-Thermal Laser Therapy

doi: 10.1097/ICO.0000000000001473

Figure Lengend Snippet: Study arm treatment parameters.

Article Snippet: Verteporfin and Non-Thermal Laser Treatment Each de-epithelialized cornea was placed into a Barron ® artificial anterior chamber and underwent a treatment protocol (see below) that included either topical Verteporfin solution (Visudyne ® ; Bausch & Lomb, Inc., Rochester, NY) alone, non-thermal laser alone, or a combination of both topical Verteporfin and non-thermal laser.

Techniques: Irradiation

Journal: Cornea

Article Title: Cornea Crosslinking with Verteporfin and Non-Thermal Laser Therapy

doi: 10.1097/ICO.0000000000001473

Figure Lengend Snippet: Corneas treated with verteporfin/six 1-minute phases of irradiation by non-thermal laser (V+NTL6) and riboflavin/ultraviolet A light (R+UVA) showed significantly more resistance to collagenase degradation than untreated corneas or corneas treated by verteporfin alone (V), non-thermal laser alone (NTL6), or verteporfin/one 1-minute phase of irradiation with non-thermal laser therapy (V+NTL1). N = 5 per group.

Article Snippet: Verteporfin and Non-Thermal Laser Treatment Each de-epithelialized cornea was placed into a Barron ® artificial anterior chamber and underwent a treatment protocol (see below) that included either topical Verteporfin solution (Visudyne ® ; Bausch & Lomb, Inc., Rochester, NY) alone, non-thermal laser alone, or a combination of both topical Verteporfin and non-thermal laser.

Techniques: Irradiation

Journal: Cornea

Article Title: Cornea Crosslinking with Verteporfin and Non-Thermal Laser Therapy

doi: 10.1097/ICO.0000000000001473

Figure Lengend Snippet: Left, photographs demonstrating the qualitative increase in stiffness of corneas treated with verteporfin/non-thermal laser (V+NTL6) and riboflavin/UVA (R+UVA) compared to untreated corneas. Right, stress-strain compression testing. The slope of the stress-strain data is observed to be steeper for corneas treated with V+NTL6 and R+UVA, suggesting that both treatments confer increased stiffness compared to untreated corneal tissue. Negative strain indicates compression in to the sample. Each color within the group represents one cornea tested (n = 5 per group). MPa = megapascals.

Article Snippet: Verteporfin and Non-Thermal Laser Treatment Each de-epithelialized cornea was placed into a Barron ® artificial anterior chamber and underwent a treatment protocol (see below) that included either topical Verteporfin solution (Visudyne ® ; Bausch & Lomb, Inc., Rochester, NY) alone, non-thermal laser alone, or a combination of both topical Verteporfin and non-thermal laser.

Techniques:

Journal: Cornea

Article Title: Cornea Crosslinking with Verteporfin and Non-Thermal Laser Therapy

doi: 10.1097/ICO.0000000000001473

Figure Lengend Snippet: Instantaneous modulus values calculated at 4%, 6%, and 8% strain for all samples tested (n = 5). Corneas treated by verteporfin/non-thermal laser (V+NTL6) exhibited larger instantaneous modulus values than untreated corneas. MPa = megapascals.

Article Snippet: Verteporfin and Non-Thermal Laser Treatment Each de-epithelialized cornea was placed into a Barron ® artificial anterior chamber and underwent a treatment protocol (see below) that included either topical Verteporfin solution (Visudyne ® ; Bausch & Lomb, Inc., Rochester, NY) alone, non-thermal laser alone, or a combination of both topical Verteporfin and non-thermal laser.

Techniques: