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tr1 cell subset  (ROHHAD Fight Inc)
90
ROHHAD Fight Inc tr1 cell subset
Immunophenotype of PBMNC. The percentage of cells expressing different lineage markers for T cells (CD3, CD3/CD8, CD4, TCRαβ, TCRγδ), B cells (CD19), NK cells (CD16, CD56), regulatory B cells (Breg, CD19, CD38, and CD24), regulatory T cells (Treg, CD4, CD25, and CD127) and type 1 regulatory T cells <t>(Tr1,</t> CD4, CD45RO, LAG-3, and CD49b) has been evaluated by flow cytometry on PBMNC cells from patients affected by ROHHAD (n = 4, black squares), ROHHAD-NET (n = 4, gray triangles), and control individuals (n = 6, white dots). Results are expressed as number of cells/μL, which has been calculated as follows: (number of lymphocytes/μL × percentage of positive cells)/100. Horizontal bars indicated medians. P values are indicated where differences are statistically significant.
Tr1 Cell Subset, supplied by ROHHAD Fight Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tr1+cell+subset/tr1+cell+subset/pmc10411042-159-0-4
Average 90 stars, based on 1 article reviews
tr1 cell subset - by Bioz Stars, 2026-10
90/100 stars
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Immunophenotype of PBMNC. The percentage of cells expressing different lineage markers for T cells (CD3, CD3/CD8, CD4, TCRαβ, TCRγδ), B cells (CD19), NK cells (CD16, CD56), regulatory B cells (Breg, CD19, CD38, and CD24), regulatory T cells (Treg, CD4, CD25, and CD127) and type 1 regulatory T cells (Tr1, CD4, CD45RO, LAG-3, and CD49b) has been evaluated by flow cytometry on PBMNC cells from patients affected by ROHHAD (n = 4, black squares), ROHHAD-NET (n = 4, gray triangles), and control individuals (n = 6, white dots). Results are expressed as number of cells/μL, which has been calculated as follows: (number of lymphocytes/μL × percentage of positive cells)/100. Horizontal bars indicated medians. P values are indicated where differences are statistically significant.

Journal: Journal of the Endocrine Society

Article Title: Blood Lymphocyte Subsets and Proinflammatory Cytokine Profile in ROHHAD(NET) and non-ROHHAD(NET) Obese Individuals

doi: 10.1210/jendso/bvad103

Figure Lengend Snippet: Immunophenotype of PBMNC. The percentage of cells expressing different lineage markers for T cells (CD3, CD3/CD8, CD4, TCRαβ, TCRγδ), B cells (CD19), NK cells (CD16, CD56), regulatory B cells (Breg, CD19, CD38, and CD24), regulatory T cells (Treg, CD4, CD25, and CD127) and type 1 regulatory T cells (Tr1, CD4, CD45RO, LAG-3, and CD49b) has been evaluated by flow cytometry on PBMNC cells from patients affected by ROHHAD (n = 4, black squares), ROHHAD-NET (n = 4, gray triangles), and control individuals (n = 6, white dots). Results are expressed as number of cells/μL, which has been calculated as follows: (number of lymphocytes/μL × percentage of positive cells)/100. Horizontal bars indicated medians. P values are indicated where differences are statistically significant.

Article Snippet: Tr1 increase in our ROHHAD(NET) cohort could represent a consequence of the autoimmune activation in our patients, to be interpreted as an ineffective attempt to control such response, but this hypothesis needs to be confirmed.

Techniques: Expressing, Flow Cytometry, Control