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Overview of type I AXL inhibitors and their current status in clinical trials for AML

Journal: Experimental Hematology & Oncology

Article Title: AXL as immune regulator and therapeutic target in Acute Myeloid Leukemia: from current progress to novel strategies

doi: 10.1186/s40164-024-00566-8

Figure Lengend Snippet: Overview of type I AXL inhibitors and their current status in clinical trials for AML

Article Snippet: TP-0903 (Dubermatinib) , Tolero Pharmaceuticals , AXL, FLT3 , 27 nM (in vitro) , NCT03013998 , Ib/II , AML , Biomarker-based multidrug therapy , Recruiting.

Techniques: Clinical Proteomics, In Vitro, Biomarker Discovery, Mutagenesis