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Neuromuscular assessment of the participants compared with reference values

Journal: Brain Communications

Article Title: Neuromuscular symptoms in patients with RYR1 -related malignant hyperthermia and rhabdomyolysis

doi: 10.1093/braincomms/fcac292

Figure Lengend Snippet: Neuromuscular assessment of the participants compared with reference values

Article Snippet: Respiratory muscle strength was tested using spirometry (SpiroUSB, Vyaire Medical connected to PC Spirometry software, Spida CareFusion version 2.3.0.10 for Windows 7).

Techniques:

Association of serum SP‐D with parameters obtained from spirometry. Local kernel‐weighted mean of ln(SP‐D) on FEV1, FVC, FEF 25%–75% and response to SABA (% increase in FEV1). Shaded areas indicate 95% confidence bands. The linear slope coefficients are presented as back‐transformed coefficients (e ln(β) ) with 95% confidence intervals from a univariate and multivariate model. The multivariate model includes adjustment for age, sex, BMI, active smoking, ethnicity, and asthma classification at follow‐up. FEF 25%–75%, forced expiratory flow 25%–75%; FEV1, forced expiratory flow rate at 1 s; FVC, forced vital capacity; SP‐D, surfactant protein D

Journal: Immunity, Inflammation and Disease

Article Title: Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults

doi: 10.1002/iid3.560

Figure Lengend Snippet: Association of serum SP‐D with parameters obtained from spirometry. Local kernel‐weighted mean of ln(SP‐D) on FEV1, FVC, FEF 25%–75% and response to SABA (% increase in FEV1). Shaded areas indicate 95% confidence bands. The linear slope coefficients are presented as back‐transformed coefficients (e ln(β) ) with 95% confidence intervals from a univariate and multivariate model. The multivariate model includes adjustment for age, sex, BMI, active smoking, ethnicity, and asthma classification at follow‐up. FEF 25%–75%, forced expiratory flow 25%–75%; FEV1, forced expiratory flow rate at 1 s; FVC, forced vital capacity; SP‐D, surfactant protein D

Article Snippet: Lung function was measured by spirometry (SpiroUSB, Carefusion Ltd), bronchodilator test was performed with salbutamol (Buventol EasyhalerTM), and mannitol provocation testing was performed using the commercially available test kit (OsmohaleTM, Pharmaxis Ltd.).

Techniques: Transformation Assay