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(a-c) Mean-normalized, fluence-corrected photoacoustic spectra vs. uncorrected spectra in targets at 5, 15, and 25 mm in the average attenuation phantom. Error bars omitted for clarity, with coefficient of variation (COV) plotted to convey signal variation over time. Black dashed lines represent the absorption spectrum of India ink from <t>spectrophotometry.</t> (d) COV of spectral measurements. (e-g) RMSD vs, target depth for all three phantom attenuation cases. (h) depth-averaged RMSD for the three attenuation cases.
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(a-c) Mean-normalized, fluence-corrected photoacoustic spectra vs. uncorrected spectra in targets at 5, 15, and 25 mm in the average attenuation phantom. Error bars omitted for clarity, with coefficient of variation (COV) plotted to convey signal variation over time. Black dashed lines represent the absorption spectrum of India ink from <t>spectrophotometry.</t> (d) COV of spectral measurements. (e-g) RMSD vs, target depth for all three phantom attenuation cases. (h) depth-averaged RMSD for the three attenuation cases.
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(a-c) Mean-normalized, fluence-corrected photoacoustic spectra vs. uncorrected spectra in targets at 5, 15, and 25 mm in the average attenuation phantom. Error bars omitted for clarity, with coefficient of variation (COV) plotted to convey signal variation over time. Black dashed lines represent the absorption spectrum of India ink from spectrophotometry. (d) COV of spectral measurements. (e-g) RMSD vs, target depth for all three phantom attenuation cases. (h) depth-averaged RMSD for the three attenuation cases.

Journal: Photoacoustics

Article Title: Evaluation of Fluence Correction Algorithms in Multispectral Photoacoustic Imaging

doi: 10.1016/j.pacs.2020.100181

Figure Lengend Snippet: (a-c) Mean-normalized, fluence-corrected photoacoustic spectra vs. uncorrected spectra in targets at 5, 15, and 25 mm in the average attenuation phantom. Error bars omitted for clarity, with coefficient of variation (COV) plotted to convey signal variation over time. Black dashed lines represent the absorption spectrum of India ink from spectrophotometry. (d) COV of spectral measurements. (e-g) RMSD vs, target depth for all three phantom attenuation cases. (h) depth-averaged RMSD for the three attenuation cases.

Article Snippet: Total transmittance and diffuse reflectance were measured over 400-1000 nm by integrating sphere spectrophotometry (Lambda 1050, PerkinElmer Inc., Waltham, MA) and the optical absorption coefficient and reduced scattering coefficient were computed using the inverse adding-doubling algorithm [ ]( ).

Techniques: Spectrophotometry